Research in Medical Biophysics Publications focuses on the application of physics in the human body and those of higher animals while examining topics such as blood flow, orthopedic mechanics, medical imaging and cancer biology. Research is conducted in partnership with clinicians at state-of-the-art facilities located at Western University, London Regional Cancer Program, Lawson Health Research Institute, Robarts Research Institute, and the London Health Sciences Centre.

Visit the Department of Medical Biophysics website for additional information.

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Submissions from 2018

Polymer Assembly Encapsulation of Lanthanide Nanoparticles as Contrast Agents for in Vivo Micro-CT, Charmainne Cruje, Joy Dunmore-Buyze, Jarret P. Macdonald, David W. Holdsworth, Maria Drangova, and Elizabeth R. Gillies

High-concentration gadolinium nanoparticles for pre-clinical vascular imaging, Charmainne Cruje, David W. Holdsworth, Elizabeth R. Gillies, and Maria Drangova

Quantitative tissue spectroscopy techniques for measuring cerebral perfusion and metabolism, Mamadou Diop

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What is the minimal clinically important difference for helium-3 magnetic resonance imaging ventilation defects?, Rachel L Eddy, Sarah Svenningsen, David G McCormack, and Grace Parraga

Chapter 3: Chemical Exchange Saturation Transfer (CEST) Contrast Agents, Giuseppe Ferrauto, Silvio Aime, Michael T. McMahon, Janet R. Morrow, Eric M. Snyder, Alex Li, and Robert Bartha

Endoscopic Laser Surface Scanner for Minimally Invasive Abdominal Surgeries, Jordan Geurten, Wenyao Xia, Uditha Jayarathne, Terry M. Peters, and Elvis C.S. Chen

Dynamic Patient-Specific Three-Dimensional Simulation of Mitral Repair: Can We Practice Mitral Repair Preoperatively?, Olivia K. Ginty, John M. Moore, Yuanwei Xu, Wenyao Xia, Satoru Fujii, Daniel Bainbridge, Terry M. Peters, Bob B. Kiaii, and Michael W.A. Chu

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Effect of wine on carotid atherosclerosis in type 2 diabetes: A 2-year randomized controlled trial, Rachel Golan, Iris Shai, Yftach Gepner, Ilana Harman-Boehm, Dan Schwarzfuchs, J David Spence, Grace Parraga, Dan Buchanan, Shula Witkow, Michael Friger, Idit F Liberty, Benjamin Sarusi, Sivan Ben-Avraham, Dana Sefarty, Nitzan Bril, Michal Rein, Noa Cohen, Uta Ceglarek, Joachim Thiery, Michael Stumvoll, Matthias Blüher, Meir J Stampfer, Assaf Rudich, and Yaakov Henkin

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Development of a pulmonary imaging biomarker pipeline for phenotyping of chronic lung disease, Fumin Guo, Dante Capaldi, Miranda Kirby, Khadija Sheikh, Sarah Svenningsen, David G McCormack, Aaron Fenster, and Grace Parraga

Automatic cancer detection and localization on prostatectomy histopathology images, W. Han, C. Johnson, M. Gaed, J. A. Gomez, M. Moussa, J. L. Chin, S. E. Pautler, G. Bauman, and A. D. Ward

Noninvasive continuous optical monitoring of absolute cerebral blood flow in critically ill adults, Lian He, Wesley B. Baker, Daniel Milej, Venkaiah C. Kavuri, Rickson C. Mesquita, David R. Busch, Kenneth Abramson, Jane Y. Jiang, Mamadou Diop, Keith St Lawrence, Olivia Amendolia, Francis Quattrone, Ramani Balu, W. Andrew Kofke, and Arjun G. Yodha

Morphology-specific discrimination between MS white matter lesions and benign white matter hyperintensities using ultra-high-field MRI, Z. Hosseini, J. Matusinec, D. A. Rudko, J. Liu, B. Y.M. Kwan, F. Salehi, M. Sharma, M. Kremenchutzky, R. S. Menon, and M. Drangova

Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer’s disease, Sheng Yao Huang, Jung Lung Hsu, Kun Ju Lin, Ho Ling Liu, Shiaw Pying Wey, Ing Tsung Hsiao, Michael Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Enchi Liu, Tom Montine, Ronald G. Thomas, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Gus Jiminez, Danielle Harvey, Matthew Bernstein, Nick Fox, Paul Thompson, Norbert Schuff, and Charles DeCarli

Monitoring joint blood flow with DCE TR-NIRS to assess treatment response in rheumatoid arthritis, Seva Ioussoufovitch, Laura B. Morrison, Lise Desjardins, Jennifer A. Hadway, Keith St Lawrence, Ting Yim Lee, Frank Beier, and Mamadou Diop

Algorithms for left atrial wall segmentation and thickness – Evaluation on an open-source CT and MRI image database, Rashed Karim, Lauren Emma Blake, Jiro Inoue, Qian Tao, Shuman Jia, R. James Housden, Pranav Bhagirath, Jean Luc Duval, Marta Varela, Jonathan Behar, Loic Cadour, Rob J. van der Geest, Hubert Cochet, Maria Drangova, Maxime Sermesant, Reza Razavi, Oleg Aslanidi, Ronak Rajani, and Kawal Rhode

Patient-specific cardiac phantom for clinical training and preprocedure surgical planning, Justin Laing, John Moore, Reid Vassallo, Daniel Bainbridge, Maria Drangova, and Terry Peters

Quantification of local geometric distortion in structural magnetic resonance images: Application to ultra-high fields, Jonathan C. Lau, Ali R. Khan, Tony Y. Zeng, Keith W. MacDougall, Andrew G. Parrent, and Terry M. Peters

18F-DCFPyL PET/CT in Oncocytoma, Jeremy Li, Richard Xu, Chun K. Kim, François Bénard, Anil Kapoor, Glenn Bauman, and Katherine A. Zukotynski

Longitudinal Measurements of Intra- and Extracellular pH Gradient in a Rat Model of Glioma, Heeseung Lim, Mohammed Albatany, Francisco Martínez-Santiesteban, Robert Bartha, and Timothy J. Scholl

Single multi-echo GRE acquisition with short and long echo spacing for simultaneous quantitative mapping of fat fraction, B0 inhomogeneity, and susceptibility, Junmin Liu, Spencer D. Christiansen, and Maria Drangova

The Utility of Penile Bulb Contouring to Localise the Prostate Apex as Compared to Urethrography, Michael I. Lock, Alicia Heinrichs, Gaurav Bhattacharya, Ellen Cusano, Robert Ash, David D'Souza, George Rodrigues, Robert Dinniwell, Varagur Venkatesan, Glenn Bauman, and Eugene Wong

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Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration, Matthias W Lorenz, Lu Gao, Kathrin Ziegelbauer, Giuseppe Danilo Norata, Jean Philippe Empana, Irene Schmidtmann, Hung-Ju Lin, Stela McLachlan, Lena Bokemark, Kimmo Ronkainen, Mauro Amato, Ulf Schminke, Sathanur R Srinivasan, Lars Lind, Shuhei Okazaki, Coen D A Stehouwer, Peter Willeit, Joseph F Polak, Helmuth Steinmetz, Dirk Sander, Holger Poppert, Moise Desvarieux, M Arfan Ikram, Stein Harald Johnsen, Daniel Staub, Cesare R Sirtori, Bernhard Iglseder, Oscar Beloqui, Gunnar Engström, Alfonso Friera, Francesco Rozza, Wuxiang Xie, Grace Parraga, Liliana Grigore, Matthieu Plichart, Stefan Blankenberg, Ta-Chen Su, Caroline Schmidt, Tomi-Pekka Tuomainen, Fabrizio Veglia, Henry Völzke, Giel Nijpels, Johann Willeit, Ralph L Sacco, Oscar H Franco, Heiko Uthoff, Bo Hedblad, Carmen Suarez, Raffaele Izzo, Dong Zhao, Thapat Wannarong, Alberico Catapano, Pierre Ducimetiere, Christine Espinola-Klein, Kuo-Liong Chien, Jackie F Price, Göran Bergström, Jussi Kauhanen, Elena Tremoli, Marcus Dörr, Gerald Berenson, Kazuo Kitagawa, Jacqueline M Dekker, Stefan Kiechl, Matthias Sitzer, Horst Bickel, Tatjana Rundek, Albert Hofman, Ellisiv B Mathiesen, Samuela Castelnuovo, Manuel F Landecho, Maria Rosvall, Rafael Gabriel, Nicola de Luca, Jing Liu, Damiano Baldassarre, Maryam Kavousi, Eric de Groot, Michiel L Bots, David N Yanez, and Simon G Thompson

Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer’s Disease using structural MR and FDG-PET images, Donghuan Lu, Karteek Popuri, Gavin Weiguang Ding, Rakesh Balachandar, Mirza Faisal Beg, Michael Weiner, Paul Aisen, Ronald Petersen, Cliford Jack, William Jagust, John Trojanowki, Arthur Toga, Laurel Beckett, Robert Green, Andrew Saykin, John C. Morris, Leslie Shaw, Jefrey Kaye, Joseph Quinn, Lisa Silbert, Betty Lind, Raina Carter, Sara Dolen, Lon Schneider, Sonia Pawluczyk, Mauricio Beccera, Liberty Teodoro, Bryan Spann, James Brewer, Helen Vanderswag, Adam Fleisher, and Judith Heidebrink

Advanced Endoscopic Navigation: Surgical Big Data, Methodology, and Applications, Xiongbiao Luo, Kensaku Mori, and Terry M. Peters

Simultaneous Surgical Visibility Assessment, Restoration, and Augmented Stereo Surface Reconstruction for Robotic Prostatectomy, Xiongbiao Luo, Ying Wan, Hui Qing Zeng, Yingying Guo, Henry Chidozie Ewurum, Xiao Bin Zhang, A. Jonathan McLeod, and Terry M. Peters