Research in Medical Biophysics Publications focuses on the application of physics in the human body and those of higher animals while examining topics such as blood flow, orthopedic mechanics, medical imaging and cancer biology. Research is conducted in partnership with clinicians at state-of-the-art facilities located at Western University, London Regional Cancer Program, Lawson Health Research Institute, Robarts Research Institute, and the London Health Sciences Centre.

Visit the Department of Medical Biophysics website for additional information.

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Submissions from 2018

Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states, Ines Mahjoub, Mohamed Ali Mahjoub, Islem Rekik, Michael Weiner, Paul Aisen, Ronald Petersen, Cliford Jack, William Jagust, John Trojanowki, Arthur Toga, Laurel Beckett, Robert Green, Andrew Saykin, John Morris, Leslie Shaw, Jefrey Kaye, Joseph Quinn, Lisa Silbert, Betty Lind, Raina Carter, Sara Dolen, Lon Schneider, Sonia Pawluczyk, Mauricio Beccera, Liberty Teodoro, Bryan Spann, James Brewer, Helen Vanderswag, Adam Fleisher, Judith Heidebrink, Joanne Lord, and Sara Mason

Emerging and Established Pulmonary Function Measurements of Primary Ciliary Dyskinesia: One of These Things Is Not Like the Others, Alexander M Matheson and Grace Parraga

Somatic gene transfer using a recombinant adenoviral vector (RAAV9) encoding pseudophosphorylated human Thr175 tau in adult rat hippocampus induces tau pathology, Alexander J. Moszczynski, Jason Gopaul, Patrick McCunn, Kathryn Volkening, Madeline Harvey, Robert Bartha rbartha@robarts.ca, Susanne Schmid, and Michael J. Strong

Pulmonary MRI morphometry modeling of airspace enlargement in chronic obstructive pulmonary disease and alpha-1 antitrypsin deficiency., Alexei Ouriadov, Eric Lessard, Khadija Sheikh, and Grace Parraga

Pathophysiology and Risk of Atrial Fibrillation Detected after Ischemic Stroke (PARADISE): A Translational, Integrated, and Transdisciplinary Approach, Maryse Paquet, Joshua O. Cerasuolo, Victoria Thorburn, Sebastian Fridman, Rasha Alsubaie, Renato D. Lopes, Lauren E. Cipriano, Paula Salamone, C. W.James Melling, Ali R. Khan, Lucas Sedeño, Jiming Fang, Maria Drangova, Manuel Montero-Odasso, Jennifer Mandzia, Alexander V. Khaw, Juan M. Racosta, Justin Paturel, Lucy Samoilov, Devin Stirling, Brittany Balint, Victoria Jaremek, Marlys L. Koschinsky, Michael B. Boffa, Kelly Summers, Agustín Ibañez, Marko Mrkobrada, Gustavo Saposnik, Kurt Kimpinski, Shawn N. Whitehead, and Luciano A. Sposato

Dual-hormone artificial pancreas: benefits and limitations compared with single-hormone systems, T. M. Peters and A. Haidar

Simultaneous monitoring of cerebral perfusion and cytochrome c oxidase by combining broadband near-infrared spectroscopy and diffuse correlation spectroscopy, Ajay Rajaram, Gemma Bale, Matthew Kewin, Laura B. Morrison, Ilias Tachtsidis, Keith St Lawrence, and Mamadou Diop

Hybrid broadband NIRS/Diffuse correlation spectroscopy system for simultaneous monitoring of cerebral perfusion and cytochrome c oxidase, Ajay Rajaram, Gemma Bale, Matthew Kewin, Ilias Tachtsidis, Keith St Lawrence, and Mamadou Diop

Motor network recovery in patients with chronic spinal cord compression: A longitudinal study following decompression surgery, Kayla Ryan, Sandy Goncalves, Robert Bartha, and Neil Duggal

1H MR spectroscopy of the motor cortex immediately following transcranial direct current stimulation at 7 Tesla, Kayla Ryan, Krzysztof Wawrzyn, Joseph S. Gati, Blaine A. Chronik, Dickson Wong, Neil Duggal, and Robert Bartha

Reduced brain glutamine in female varsity rugby athletes after concussion and in non-concussed athletes after a season of play, Amy L. Schranz, Kathryn Y. Manning, Gregory A. Dekaban, Lisa Fischer, Tatiana Jevremovic, Kevin Blackney, Christy Barreira, Timothy J. Doherty, Douglas D. Fraser, Arthur Brown, Jeff Holmes, Ravi S. Menon, and Robert Bartha

An Aspartyl Cathepsin Targeted PET Agent: Application in an Alzheimer's Disease Mouse Model, Jonatan A. Snir, Mojmir Suchy, Geron A. Bindseil, Michael Kovacs, Blaine A. Chronik, Robert H.E. Hudson, Stephen H. Pasternak, and Robert Bartha

Chapter 4: Iron-oxide Nanoparticle-based Contrast Agents, Dimitri Stanicki, Luce Vander Elst, Robert N. Muller, Sophie Laurent, Delphine Felder-Flesch, Damien Mertz, Audrey Parat, Sylvie Begin-Colin, Geoffrey Cotin, Jean Marc Greneche, Ovidiu Ersen, Benoit Pichon, Vlad Socoliuc, Victor Kuncser, Rodica Turcu, Ladislau Vékás, Paula Foster, and Robert Bartha

Chapter 6: Fluorine-based Contrast Agents, Emma Stares, Junsung Rho, Eric T. Ahrens, Paula Foster, Alex Li, and Robert Bartha

Sputum Eosinophilia and Magnetic Resonance Imaging Ventilation Heterogeneity in Severe Asthma, Sarah Svenningsen, Rachel L Eddy, Hui Fang Lim, P Gerard Cox, Parameswaran Nair, and Grace Parraga

Dual-energy computed tomography using a gantry-based preclinical cone-beam microcomputed tomography scanner, Justin J. Tse, Joy Dunmore-Buyze, Maria Drangova, and David W. Holdsworth

Corrigendum to: Erbium-based perfusion contrast agent for small-animal microvessel imaging (Contrast Media and Molecular Imaging (2017) 2017 (7368384) DOI: 10.1155/2017/7368384), Justin J. Tse, P. Joy Dunmore-Buyze, Maria Drangova, and David W. Holdsworth

A mold design for creating low-cost patient specific models with complex anatomy, Reid Vassallo, Daniel Bainbridge, John Moore, and Terry Peters

Augmented reality guidance in cerebrovascular surgery using microscopic video enhancement, Reid Vassallo, Hidetoshi Kasuya, Benjamin W.Y. Lo, Terry Peters, and Yiming Xiao

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68 Ga-Labeled Prostate-specific Membrane Antigen Ligand Positron Emission Tomography/Computed Tomography for Prostate Cancer: A Systematic Review and Meta-analysis, Finn E. von Eyben, Maria Picchio, Rie von Eyben, Handoo Rhee, and Glenn Bauman

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COPD biomarkers and phenotypes: Opportunities for better outcomes with precision imaging, George R Washko and Grace Parraga

Optimized in vivo brain glutamate measurement using long-echo-time semi-LASER at 7 T, Dickson Wong, Amy L. Schranz, and Robert Bartha

Endoscopic image enhancement with noise suppression, Wenyao Xia, Elvis C.S. Chen, and Terry Peters

Signal dropout correction-based ultrasound segmentation for diastolic mitral valve modeling, Wenyao Xia, John Moore, Elvis C.S. Chen, Yuanwei Xu, Olivia Ginty, Daniel Bainbridge, and Terry M. Peters

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference, Alexandra L. Young, Razvan V. Marinescu, Neil P. Oxtoby, Martina Bocchetta, Keir Yong, Nicholas C. Firth, David M. Cash, David L. Thomas, Katrina M. Dick, Jorge Cardoso, John van Swieten, Barbara Borroni, Daniela Galimberti, Mario Masellis, Maria Carmela Tartaglia, James B. Rowe, Caroline Graff, Fabrizio Tagliavini, Giovanni B. Frisoni, Robert Laforce, Elizabeth Finger, Alexandre de Mendonça, Sandro Sorbi, Jason D. Warren, Sebastian Crutch, Nick C. Fox, Sebastien Ourselin, Jonathan M. Schott, Jonathan D. Rohrer, Daniel C. Alexander, Christin Andersson, and Silvana Archetti