Chapter 6: Fluorine-based Contrast Agents

Document Type

Article

Publication Date

1-1-2018

Journal

New Developments in NMR

Volume

2018-January

Issue

13

First Page

479

Last Page

498

URL with Digital Object Identifier

10.1039/9781788010146-00479

Abstract

This chapter focuses on fluorine-based probes and pays particular attention to their use for cell tracking with MRI. Most of these probes incorporate perfluorocarbon molecules that are formulated as colloidal suspensions or emulsions in aqueous buffer. A discussion on the design of fluorine probes and emulsions is followed by a description of the acquisition of 19F MRI phantoms.

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