Research in Medical Biophysics Publications focuses on the application of physics in the human body and those of higher animals while examining topics such as blood flow, orthopedic mechanics, medical imaging and cancer biology. Research is conducted in partnership with clinicians at state-of-the-art facilities located at Western University, London Regional Cancer Program, Lawson Health Research Institute, Robarts Research Institute, and the London Health Sciences Centre.
Visit the Department of Medical Biophysics website for additional information.
Submissions from 2019
Stereotactic ablative radiotherapy for the comprehensive treatment of 4-10 oligometastatic tumors (SABR-COMET-10): Study protocol for a randomized phase III trial, David A. Palma, Robert Olson, Stephen Harrow, Rohann J.M. Correa, Famke Schneiders, Cornelis J.A. Haasbeek, George B. Rodrigues, Michael Lock, Brian P. Yaremko, Glenn S. Bauman, Belal Ahmad, Devin Schellenberg, Mitchell Liu, Stewart Gaede, Joanna Laba, Liam Mulroy, Sashendra Senthi, Alexander V. Louie, Anand Swaminath, Anthony Chalmers, Andrew Warner, Ben J. Slotman, Tanja D. De Gruijl, Alison Allan, and Suresh Senan
A three-gene DNA methylation biomarker accurately classifies early stage prostate cancer, Palak G. Patel, Thomas Wessel, Atsunari Kawashima, John B.A. Okello, Tamara Jamaspishvili, Karl Philippe Guérard, Laura Lee, Anna Ying Wah Lee, Nathan E. How, Dan Dion, Eleonora Scarlata, Chelsea L. Jackson, Suzanne Boursalie, Tanya Sack, Rachel Dunn, Madeleine Moussa, Karen Mackie, Audrey Ellis, Elizabeth Marra, Joseph Chin, Khurram Siddiqui, Khalil Hetou, Lee Anne Pickard, Vinolia Arthur-Hayward, Glenn Bauman, Simone Chevalier, Fadi Brimo, Paul C. Boutros, Jacques Lapointe PhD, John M.S. Bartlett, Robert J. Gooding, and David M. Berman
The Canadian Dementia Imaging Protocol: Harmonization validity for morphometry measurements, Olivier Potvin, Isabelle Chouinard, Louis Dieumegarde, Robert Bartha, Pierre Bellec, D. Louis Collins, Maxime Descoteaux, Rick Hoge, Joel Ramirez, Christopher J.M. Scott, Eric E. Smith, Stephen C. Strother, Sandra E. Black, and Simon Duchesne
Functional network resilience to pathology in presymptomatic genetic frontotemporal dementia, Timothy Rittman, Robin Borchert, Simon Jones, John van Swieten, Barbara Borroni, Daniela Galimberti, Mario Masellis, Maria Carmela Tartaglia, Caroline Graff, Fabrizio Tagliavini, Giovanni B. Frisoni, Robert Laforce, Elizabeth Finger, Alexandre Mendonça, Sandro Sorbi, Jonathan D. Rohrer, James B. Rowe, Sónia Afonso, Maria Rosario Almeida, Sarah Anderl-Straub, Christin Andersson, Anna Antonell, Silvana Archetti, Andrea Arighi, Mircea Balasa, Myriam Barandiaran, Nuria Bargalló, Robart Bartha, Benjamin Bender, Luisa Benussi, Valentina Bessi, and Giuliano Binetti
Differential effects of transcranial direct current stimulation on antiphase and inphase motor tasks: A pilot study, Kayla Ryan, Amy L. Schranz, Neil Duggal, and Robert Bartha
Entorhinal cortex volume is associated with dual-task gait cost among older adults with MCI: Results from the gait and brain study, Ryota Sakurai, Robert Bartha, and Manuel Montero-Odasso
Visualization of the Small Airways:What It Is and Why It Matters, Mark L Schiebler and Grace Parraga
Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer’s Dementia, Lucas Porcello Schilling, Tharick A. Pascoal, Eduardo R. Zimmer, Sulantha Mathotaarachchi, Monica Shin, Carlos Roberto de Mello Rieder, Serge Gauthier, André Palmini, Pedro Rosa-Neto, Michael W. Weiner, Paul Aisen, Ronald Petersen, Ronald Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Jeffrey Kaye, Joseph Quinn, Lisa Silbert, Betty Lind, Raina Carter, Sara Dolen, Lon S. Schneider, Sonia Pawluczyk, Mauricio Beccera, Liberty Teodoro, and Bryan M. Spann
Preface, Dinggang Shen, Tianming Liu, Terry M. Peters, Lawrence H. Staib, Caroline Essert, Sean Zhou, Pew Thian Yap, and Ali Khan
Preface, Dinggang Shen, Tianming Liu, Terry M. Peters, Lawrence H. Staib, Caroline Essert, Sean Zhou, Pew Thian Yap, and Ali Khan
Ambroxol as a novel disease-modifying treatment for Parkinson's disease dementia: Protocol for a single-centre, randomized, double-blind, placebo-controlled trial, C. R.A. Silveira, J. MacKinley, K. Coleman, Z. Li, E. Finger, R. Bartha, S. A. Morrow, J. Wells, M. Borrie, R. G. Tirona, C. A. Rupar, G. Zou, R. A. Hegele, D. Mahuran, Penny A. MacDonald, M. E. Jenkins, M. Jog, and S. H. Pasternak
White matter integrity is associated with gait impairment and falls in mild cognitive impairment. Results from the gait and brain study, Jonatan A. Snir, Robert Bartha, and Manuel Montero-Odasso
The utility of multivariate outlier detection techniques for data quality evaluation in large studies: An application within the ONDRI project, Kelly M. Sunderland, Derek Beaton, Julia Fraser, Donna Kwan, Paula M. McLaughlin, Manuel Montero-Odasso, Alicia J. Peltsch, Frederico Pieruccini-Faria, Demetrios J. Sahlas, Richard H. Swartz, Robert Bartha, Sandra E. Black, Michael Borrie, Dale Corbett, Elizabeth Finger, Morris Freedman, Barry Greenberg, David A. Grimes, Robert A. Hegele, Chris Hudson, Anthony E. Lang, Mario Masellis, William E. McIlroy, David G. Munoz, Douglas P. Munoz, J. B. Orange, Michael J. Strong, Sean Symons, Maria Carmela Tartaglia, Angela Troyer, Lorne Zinman, and Stephen C. Strother
Normalisation of MRI ventilation heterogeneity in severe asthma by dupilumab, Sarah Svenningsen, Ehsan Ahmed Haider, Rachel L Eddy, Grace Parraga, and Parameswaran Nair
CT and Functional MRI to Evaluate Airway Mucus in Severe Asthma, Sarah Svenningsen, Ehsan Haider, Colm Boylan, Manali Mukherjee, Rachel L Eddy, Dante P I Capaldi, Grace Parraga, and Parameswaran Nair
Ventricular volume expansion in presymptomatic genetic frontotemporal dementia, Tamara P. Tavares, Derek G.V. Mitchell, Kristy Coleman, Christen Shoesmith, Robert Bartha, David M. Cash, Katrina M. Moore, John Van Swieten, Barbara Borroni, Daniela Galimberti, Maria Carmela Tartaglia, James Rowe, Caroline Graff, Fabrizio Tagliavini, Giovanni Frisoni, Stefano Cappa, Robert Laforce, Alexandre De Mendonça, Sandro Sorbi, Garrick Wallstrom, Mario Masellis, Jonathan D. Rohrer, and Elizabeth C. Finger
How Accurately Does Transesophageal Echocardiography Identify the Mitral Valve?, Claire Vannelli, Wenyao Xia, John Moore, and Terry Peters
Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics, Yogatheesan Varatharajah, Vijay K. Ramanan, Ravishankar Iyer, Prashanthi Vemuri, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, Andrew J. Saykin, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, John Morris, Leslie M. Shaw, Zaven Khachaturian, Greg Sorensen, Maria Carrillo, Lew Kuller, Marc Raichle, Steven Paul, Peter Davies, Howard Fillit, Franz Hefti, David Holtzman, M. Marcel Mesulam, William Potter, Peter Snyder, Adam Schwartz, Tom Montine, and Ronald G. Thomas
Determining blood flow direction from short neurovascular surgical microscope videos, Reid Vassallo, Adam Rankin, Stephen P. Lownie, Hitoshi Fukuda, Hidetoshi Kasuya, Benjamin W.Y. Lo, Terry Peters, and Yiming Xiao
Chronic Obstructive Pulmonary Disease: Thoracic CT Texture Analysis and Machine Learning to Predict Pulmonary Ventilation, Andrew Westcott, Dante P I Capaldi, David G McCormack, Aaron D Ward, Aaron Fenster, and Grace Parraga
Hyperpolarized 3He MRI Ventilatory Apparent Diffusion Coefficient of Alpha-1 Antitrypsin, Andrew Westcott, Dante P I Capaldi, Alexei Ouriadov, David G McCormack, and Grace Parraga
Rapid single-breath hyperpolarized noble gas MRI-based biomarkers of airspace enlargement, Andrew Westcott, Fumin Guo, Grace Parraga, and Alexei Ouriadov
Advanced pulmonary MRI to quantify alveolar and acinar duct abnormalities: Current status and future clinical applications, Andrew Westcott, David G McCormack, Grace Parraga, and Alexei Ouriadov
Methodological consensus on clinical proton MRS of the brain: Review and recommendations, Martin Wilson, Ovidiu Andronesi, Peter B. Barker, Robert Bartha, Alberto Bizzi, Patrick J. Bolan, Kevin M. Brindle, In Young Choi, Cristina Cudalbu, Ulrike Dydak, Uzay E. Emir, Ramon G. Gonzalez, Stephan Gruber, Rolf Gruetter, Rakesh K. Gupta, Arend Heerschap, Anke Henning, Hoby P. Hetherington, Petra S. Huppi, Ralph E. Hurd, Kejal Kantarci, Risto A. Kauppinen, Dennis W.J. Klomp, Roland Kreis, Marijn J. Kruiskamp, Martin O. Leach, Alexander P. Lin, Peter R. Luijten, Małgorzata Marjańska, Andrew A. Maudsley, Dieter J. Meyerhoff, and Carolyn E. Mountford
An accurate registration of the BigBrain dataset with the MNI PD25 and ICBM152 atlases, Yiming Xiao, Jonathan C. Lau, Taylor Anderson, Jordan DeKraker, D. Louis Collins, Terry Peters, and Ali R. Khan