Research in Medical Biophysics Publications focuses on the application of physics in the human body and those of higher animals while examining topics such as blood flow, orthopedic mechanics, medical imaging and cancer biology. Research is conducted in partnership with clinicians at state-of-the-art facilities located at Western University, London Regional Cancer Program, Lawson Health Research Institute, Robarts Research Institute, and the London Health Sciences Centre.

Visit the Department of Medical Biophysics website for additional information.


Submissions from 2020

Using fMRI to investigate the potential cause of inverse oxygenation reported in fNIRS studies of motor imagery, Androu Abdalmalak, Daniel Milej, David J. Cohen, Udunna Anazodo, Tracy Ssali, Mamadou Diop, Adrian M. Owen, and Keith St. Lawrence

Assessing Time-Resolved fNIRS for Brain-Computer Interface Applications of Mental Communication, Androu Abdalmalak, Daniel Milej, Lawrence C.M. Yip, Ali R. Khan, Mamadou Diop, Adrian M. Owen, and Keith St. Lawrence

Reduced Cognitive Assessment Scores Among Individuals With Magnetic Resonance Imaging-Detected Vascular Brain Injury, Sonia S Anand, Matthias G Friedrich, Dipika Desai, Karleen M Schulze, Philip Awadalla, David Busseuil, Trevor J B Dummer, Sébastien Jacquemont, Alexander Dick, David Kelton, Anish Kirpalani, Scott A Lear, Jonathan Leipsic, Michael D Noseworthy, Louise Parker, Grace Parraga, Paul Poirier, Paula Robson, Jean-Claude Tardif, Koon Teo, Jennifer Vena, Salim Yusuf, Alan R Moody, Sandra E Black, and Eric E Smith


Pulmonary xenon-129 MRI: New opportunities to unravel enigmas in respiratory medicine, Rachel L Eddy and Grace Parraga

Is Computed Tomography Airway Count Related to Asthma Severity and Airway Structure and Function?, Rachel L Eddy, Sarah Svenningsen, Miranda Kirby, Danielle Knipping, David G McCormack, Christopher Licskai, Parameswaran Nair, and Grace Parraga

Quantification of joint blood flow by dynamic contrast-enhanced near-infrared spectroscopy: Application to monitoring disease activity in a rat model of rheumatoid arthritis, Seva Ioussoufovitch, Laura B. Morrison, Lise Desjardins, Jennifer A. Hadway, Keith St Lawrence, Ting Yim Lee, Frank Beier, and Mamadou Diop


Pulmonary Imaging Phenotypes of Chronic Obstructive Pulmonary Disease Using Multiparametric Response Maps, Jonathan L MacNeil, Dante P I Capaldi, Andrew R Westcott, Rachel L Eddy, Andrea L Barker, David G McCormack, Miranda Kirby, and Grace Parraga


FEV1 and MRI Ventilation Defect Reversibility in Asthma and COPD, Hana Serajeddini, Rachel L Eddy, Christopher Licskai, David G McCormack, and Grace Parraga

Submissions from 2019


Cardiovascular risk scoring and magnetic resonance imaging detected subclinical cerebrovascular disease, Sonia S Anand, Jack V Tu, Dipika Desai, Phillip Awadalla, Paula Robson, Sébastien Jacquemont, Trevor Dummer, Nhu Le, Louise Parker, Paul Poirier, Koon Teo, Scott A Lear, Salim Yusuf, Jean-Claude Tardif, Francois Marcotte, David Busseuil, Jean-Pierre Després, Sandra E Black, Anish Kirpalani, Grace Parraga, Michael D Noseworthy, Alexander Dick, Jonathan Leipsic, David Kelton, Jennifer Vena, Melissa Thomas, Karleen M Schulze, Eric Larose, Alan R Moody, Eric E Smith, and Matthias G Friedrich

Multimodal measurements of brain tissue metabolism and perfusion in a neonatal model of hypoxic-ischaemic injury, Gemma Bale, Ajay Rajaram, Matthew Kewin, Laura Morrison, Alan Bainbridge, Linshan Liu, Udunna Anazodo, Mamadou Diop, Keith St Lawrence, and Ilias Tachtsidis

In silico investigation of near-infrared light propagation in the joints of the human hand, David Cohen and Mamadou Diop


Nonidentical twins with asthma: Spatially matched CT airway and MRI ventilation abnormalities, Rachel L Eddy, Alexander M Matheson, Sarah Svenningsen, Danielle Knipping, Christopher Licskai, David G McCormack, and Grace Parraga


Hyperpolarized Helium 3 MRI in Mild-to-Moderate Asthma: Prediction of Postbronchodilator Reversibility, Rachel L Eddy, Sarah Svenningsen, Christopher Licskai, David G McCormack, and Grace Parraga


Oscillometry and pulmonary magnetic resonance imaging in asthma and COPD, Rachel L Eddy, Andrew Westcott, Geoffrey N Maksym, Grace Parraga, and Ronald J Dandurand

Extending the dynamic range of biomedical micro-computed tomography for application to geomaterials., D R Edey, S I Pollmann, D Lorusso, M Drangova, R L Flemming, and D W Holdsworth


Eliminating the effects of motion during radiofrequency lesion delivery using a novel contact-force controller., Daniel Gelman, Allan C Skanes, Douglas L Jones, Michael Timofeyev, Tal Bar-On, and Maria Drangova

A framework for Fourier-decomposition free-breathing pulmonary 1H MRI ventilation measurements, Fumin Guo, Dante P I Capaldi, David G McCormack, Aaron Fenster, and Grace Parraga

Quantifying joint blood flow in a rat model of rheumatoid arthritis with dynamic contrast-enhanced near-infrared spectroscopy, Seva Ioussoufovitch, Laura B. Morrison, Lise Desjardins, Jennifer A. Hadway, Keith St Lawrence, Ting Yim Lee, Frank Beier, and Mamadou Diop

Incorporating Pathology-Induced Heterogeneities in a Patient-Specific Biomechanical Model of the Lung for Accurate Tumor Motion Estimation., Parya Jafari, Douglas A Hoover, Brian P Yaremko, Grace Parraga, Abbas Samani, and Ali Sadeghi-Naini

4DCT Ventilation Map Construction Using Biomechanics-base Image Registration and Enhanced Air Segmentation., Parya Jafari, Brian P Yaremko, Grace Parraga, Douglas A Hoover, Ali Sadeghi-Naini, and Abbas Samani

Evaluation of hyperspectral NIRS for quantitative measurements of tissue oxygen saturation by comparison to time-resolved NIRS, Matthew Kewin, Ajay Rajaram, Daniel Milej, Androu Abdalmalak, Laura Morrison, Mamadou Diop, and Keith St Lawrence

Development of a stand-alone DCS system for monitoring absolute cerebral blood flow, Mahro Khalid, Daniel Milej, Ajay Rajaram, Androu Abdalmalak, Laura Morrison, Mamadou Diop, and Keith S.T. Lawrence


Accelerated 129Xe MRI morphometry of terminal airspace enlargement: Feasibility in volunteers and those with alpha-1 antitrypsin deficiency, Alexei Ouriadov, Fumin Guo, David G McCormack, and Grace Parraga


Visualization of the Small Airways:What It Is and Why It Matters, Mark L Schiebler and Grace Parraga


Normalisation of MRI ventilation heterogeneity in severe asthma by dupilumab, Sarah Svenningsen, Ehsan Ahmed Haider, Rachel L Eddy, Grace Parraga, and Parameswaran Nair