Research in Medical Biophysics Publications focuses on the application of physics in the human body and those of higher animals while examining topics such as blood flow, orthopedic mechanics, medical imaging and cancer biology. Research is conducted in partnership with clinicians at state-of-the-art facilities located at Western University, London Regional Cancer Program, Lawson Health Research Institute, Robarts Research Institute, and the London Health Sciences Centre.
Visit the Department of Medical Biophysics website for additional information.
Submissions from 2020
Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration, Nicolai Franzmeier, M. Suárez-Calvet, Lukas Frontzkowski, Annah Moore, Timothy J. Hohman, Estrella Morenas-Rodriguez, Brigitte Nuscher, Leslie Shaw, John Q. Trojanowski, Martin Dichgans, Gernot Kleinberger, Christian Haass, Michael Ewers, Michael Weiner, Paul Aisen, Gerald Novak, Robert C. Green, Tom Montine, Ronald Petersen, Anthony Gamst, Ronald G. Thomas, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Laurel Beckett, Danielle Harvey, John Kornak, Clifford R. Jack, Anders Dale, Matthew Bernstein, and Joel Felmlee
Left atrial vortex size and velocity distributions by 4D flow MRI in patients with paroxysmal atrial fibrillation: Associations with age and CHA2DS2-VASc risk score, Julio Garcia, Hana Sheitt, Michael S. Bristow, Carmen Lydell, Andrew G. Howarth, Bobak Heydari, Frank S. Prato, Maria Drangova, Rebecca E. Thornhill, Pablo Nery, Stephen B. Wilton, Allan Skanes, and James A. White
Striatal Acetylcholine Helps to Preserve Functional Outcomes in a Mouse Model of Stroke, Daniela F. Goncalves, Monica S. Guzman, Robert Gros, André R. Massensini, Robert Bartha, Vania F. Prado, and Marco A.M. Prado
Dosimetric Evaluation of PSMA PET-Delineated Dominant Intraprostatic Lesion Simultaneous Infield Boosts, Christopher D. Goodman, Hatim Fakir, Stephen Pautler, Joseph Chin, and Glenn S. Bauman
Automatic segmentation of the carotid artery and internal jugular vein from 2D ultrasound images for 3D vascular reconstruction, Leah A. Groves, Blake VanBerlo, Natan Veinberg, Abdulrahman Alboog, Terry M. Peters, and Elvis C.S. Chen
Histologic tissue components provide major cues for machine learning-based prostate cancer detection and grading on prostatectomy specimens, Wenchao Han, Carol Johnson, Mena Gaed, José A. Gómez, Madeleine Moussa, Joseph L. Chin, Stephen Pautler, Glenn S. Bauman, and Aaron D. Ward
Automatic cancer detection on digital histopathology images of mid-gland radical prostatectomy specimens, Wenchao Han, Carol Johnson, Andrew Warner, Mena Gaed, Jose A. Gomez, Madeleine Moussa, Joseph Chin, Stephen Pautler, Glenn Bauman, and Aaron D. Ward
Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia, Carolin Heller, Martha S. Foiani, Katrina Moore, Rhian Convery, Martina Bocchetta, Mollie Neason, David M. Cash, David Thomas, Caroline V. Greaves, Ione O.C. Woollacott, Rachelle Shafei, John C. van Swieten, Fermin Moreno, Raquel Sanchez-Valle, Barbara Borroni, Robert Laforce, Mario Masellis, Maria Carmela Tartaglia, Caroline Graff, Daniela Galimberti, James B. Rowe, Elizabeth Finger, Matthis Synofzik, Rik Vandenberghe, Alexandre de Mendonca, Fabrizio Tagliavini, Isabel Santana, Simon Ducharme, Christopher R. Butler, Alex Gerhard, Johannes Levin, and Adrian Danek
Quantification of joint blood flow by dynamic contrast-enhanced near-infrared spectroscopy: Application to monitoring disease activity in a rat model of rheumatoid arthritis, Seva Ioussoufovitch, Laura B. Morrison, Lise Desjardins, Jennifer A. Hadway, Keith St Lawrence, Ting Yim Lee, Frank Beier, and Mamadou Diop
Optimization of multi-electrode implant configurations and programming for the delivery of non-ablative electric fields in intratumoral modulation therapy., Erin Iredale, Andrew Deweyert, Douglas A Hoover, Jeff Z Chen, Susanne Schmid, Matthew O Hebb, Terry M Peters, and Eugene Wong
Structural Brain Magnetic Resonance Imaging to Rule out Comorbid Pathology in the Assessment of Alzheimer's Disease Dementia: Findings from the Ontario Neurodegenerative Disease Research Initiative (ONDRI) Study and Clinical Trials over the Past 10 Years, Arunima Kapoor, Robert Bartha, Sandra E. Black, Michael Borrie, Morris Freedman, Fuqiang Gao, Nathan Herrmann, Jennifer Mandzia, Miracle Ozzoude, Joel Ramirez, Christopher J.M. Scott, Sean Symons, Corinne E. Fischer, Andrew Frank, Dallas Seitz, Michael Uri Wolf, Nicolaas Paul L.G. Verhoeff, Gary Naglie, William Reichman, Mario Masellis, Sara B. Mitchell, David F. Tang-Wai, Maria Carmela Tartaglia, Sanjeev Kumar, Bruce G. Pollock, Tarek K. Rajji, Elizabeth Finger, Stephen H. Pasternak, and Richard H. Swartz
Direct visualization and characterization of the human zona incerta and surrounding structures, Jonathan C. Lau, Yiming Xiao, Roy A.M. Haast, Greydon Gilmore, Kâmil Uludağ, Keith W. MacDougall, Ravi S. Menon, Andrew G. Parrent, Terry M. Peters, and Ali R. Khan
Glutamate and Dysconnection in the Salience Network: Neurochemical, Effective Connectivity, and Computational Evidence in Schizophrenia, Roberto Limongi, Peter Jeon, Michael Mackinley, Tushar Das, Kara Dempster, Jean Théberge, Robert Bartha, Dickson Wong, and Lena Palaniyappan
A Prospective Study of 18F-DCFPyL PSMA PET/CT Restaging in Recurrent Prostate Cancer following Primary External Beam Radiotherapy or Brachytherapy, Wei Liu, Katherine Zukotynski, Louise Emmett, Hans T. Chung, Peter Chung, Robert Wolfson, Irina Rachinsky, Anil Kapoor, Ur Metser, Andrew Loblaw, Gerard Morton, Tracy Sexton, Michael Lock, Joelle Helou, Alejandro Berlin, Colm Boylan, Susan Archer, Gregory R. Pond, and Glenn Bauman
Pulmonary Imaging Phenotypes of Chronic Obstructive Pulmonary Disease Using Multiparametric Response Maps, Jonathan L MacNeil, Dante P I Capaldi, Andrew R Westcott, Rachel L Eddy, Andrea L Barker, David G McCormack, Miranda Kirby, and Grace Parraga
Longitudinal changes of brain microstructure and function in nonconcussed female rugby players, Kathryn Y. Manning, Jeffrey S. Brooks, James P. Dickey, Alexandra Harriss, Lisa Fischer, Tatiana Jevremovic, Kevin Blackney, Christy Barreira, Arthur Brown, Robert Bartha, Tim Doherty, Douglas Fraser, Jeff Holmes, Gregory A. Dekaban, and Ravi S. Menon
Is hypofractionated whole pelvis radiotherapy (WPRT) as well tolerated as conventionally fractionated WPRT in prostate cancer patients? The HOPE trial, Lucas C. Mendez, Andrew J. Arifin, Glenn S. Bauman, Vikram M. Velker, Belal Ahmad, Michael Lock, Varagur M. Venkatesan, Tracy L. Sexton, George B. Rodrigues, Jeff Chen, Bryan Schaly, Andrew Warner, and David P. D'Souza
Augmented reality simulator for ultrasound-guided percutaneous renal access, Yanyu Mu, David Hocking, Zhan Tao Wang, Gregory J. Garvin, Roy Eagleson, and Terry M. Peters
A simple, realistic walled phantom for intravascular and intracardiac applications, Hareem Nisar, John Moore, Roberta Piazza, Efthymios Maneas, Elvis C.S. Chen, and Terry M. Peters
Neural effects of oxytocin and mimicry in frontotemporal dementia: A randomized crossover study, Lindsay D. Oliver, Chloe Stewart, Kristy Coleman, James H. Kryklywy, Robert Bartha, Derek G.V. Mitchell, and Elizabeth C. Finger
Cortical Thickness Estimation in Individuals With Cerebral Small Vessel Disease, Focal Atrophy, and Chronic Stroke Lesions, Miracle Ozzoude, Joel Ramirez, Pradeep Reddy Raamana, Melissa F. Holmes, Kirstin Walker, Christopher J.M. Scott, Fuqiang Gao, Maged Goubran, Donna Kwan, Maria C. Tartaglia, Derek Beaton, Gustavo Saposnik, Ayman Hassan, Jane Lawrence-Dewar, Dariush Dowlatshahi, Stephen C. Strother, Sean Symons, Robert Bartha, Richard H. Swartz, and Sandra E. Black
Beyond Oligometastases, David A. Palma, Glenn S. Bauman, and George B. Rodrigues
Towards electromagnetic tracking of J-tip guidewire: Precision assessment of sensors during bending tests, Roberta Piazza, Hareem Nisar, John Moore, Sara Condino, Mauro Ferrari, Vincenzo Ferrari, Terry M. Peters, and Elvis C.S. Chen
Ontario Neurodegenerative Disease Research Initiative (ONDRI): Structural MRI Methods and Outcome Measures, Joel Ramirez, Melissa F. Holmes, Christopher J.M. Scott, Miracle Ozzoude, Miracle Ozzoude, Sabrina Adamo, Gregory M. Szilagyi, Maged Goubran, Fuqiang Gao, Stephen R. Arnott, Jane M. Lawrence-Dewar, Jane M. Lawrence-Dewar, Derek Beaton, Stephen C. Strother, Douglas P. Munoz, Mario Masellis, Richard H. Swartz, Robert Bartha, Sean P. Symons, Sandra E. Black, Michael Strong, Peter Kleinstiver, Natalie Rashkovan, Susan Bronskill, Sandra E. Black, Michael Borrie, Elizabeth Finger, Corinne Fischer, Andrew Frank, Morris Freedman, Sanjeev Kumar, and Stephen Pasternak
Social cognition impairment in genetic frontotemporal dementia within the GENFI cohort, Lucy L. Russell, Caroline V. Greaves, Martina Bocchetta, Jennifer Nicholas, Rhian S. Convery, Katrina Moore, David M. Cash, John van Swieten, Lize Jiskoot, Fermin Moreno, Raquel Sanchez-Valle, Barbara Borroni, Robert Laforce, Mario Masellis, Maria Carmela Tartaglia, Caroline Graff, Emanuela Rotondo, Daniela Galimberti, James B. Rowe, Elizabeth Finger, Matthis Synofzik, Rik Vandenberghe, Alexandre de Mendonça, Fabrizio Tagliavini, Isabel Santana, Simon Ducharme, Chris Butler, Alex Gerhard, Johannes Levin, Adrian Danek, Markus Otto, and Jason D. Warren