Research in Medical Biophysics Publications focuses on the application of physics in the human body and those of higher animals while examining topics such as blood flow, orthopedic mechanics, medical imaging and cancer biology. Research is conducted in partnership with clinicians at state-of-the-art facilities located at Western University, London Regional Cancer Program, Lawson Health Research Institute, Robarts Research Institute, and the London Health Sciences Centre.

Visit the Department of Medical Biophysics website for additional information.


Submissions from 2019

Quantifying joint blood flow in a rat model of rheumatoid arthritis with dynamic contrast-enhanced near-infrared spectroscopy, Seva Ioussoufovitch, Laura B. Morrison, Lise Desjardins, Jennifer A. Hadway, Keith St Lawrence, Ting Yim Lee, Frank Beier, and Mamadou Diop

Incorporating Pathology-Induced Heterogeneities in a Patient-Specific Biomechanical Model of the Lung for Accurate Tumor Motion Estimation., Parya Jafari, Douglas A Hoover, Brian P Yaremko, Grace Parraga, Abbas Samani, and Ali Sadeghi-Naini

4DCT Ventilation Map Construction Using Biomechanics-base Image Registration and Enhanced Air Segmentation., Parya Jafari, Brian P Yaremko, Grace Parraga, Douglas A Hoover, Ali Sadeghi-Naini, and Abbas Samani

Robust, Intrinsic Tracking of a Laparoscopic Ultrasound Probe for Ultrasound-Augmented Laparoscopy, Uditha L. Jayarathne, Elvis C.S. Chen, John Moore, and Terry M. Peters


Semiautomated Assessment of the Anterior Cingulate Cortex in Alzheimer's Disease, Flora Jung, Samaneh Kazemifar, Robert Bartha, and Nagalingam Rajakumar

Evaluation of hyperspectral NIRS for quantitative measurements of tissue oxygen saturation by comparison to time-resolved NIRS, Matthew Kewin, Ajay Rajaram, Daniel Milej, Androu Abdalmalak, Laura Morrison, Mamadou Diop, and Keith St Lawrence

Development of a stand-alone DCS system for monitoring absolute cerebral blood flow, Mahro Khalid, Daniel Milej, Ajay Rajaram, Androu Abdalmalak, Laura Morrison, Mamadou Diop, and Keith S.T. Lawrence

A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data, Suprateek Kundu, Joshua Lukemire, Yikai Wang, Ying Guo, Michael W. Weiner, Norbert Schuff, Howard J. Rosen, Bruce L. Miller, Thomas Neylan, Jacqueline Hayes, Shannon Finley, Paul Aisen, Zaven Khachaturian, Ronald G. Thomas, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Gus Jiminez, Leon Thal, James Brewer, Helen Vanderswag, Adam Fleisher, Melissa Davis, Rosemary Morrison, Ronald Petersen, Clifford R. Jack, Matthew Bernstein, Bret Borowski, Jeff Gunter, Matt Senjem, and Prashanthi Vemuri

A framework for evaluating correspondence between brain images using anatomical fiducials, Jonathan C. Lau, Andrew G. Parrent, John Demarco, Geetika Gupta, Jason Kai, Olivia W. Stanley, Tristan Kuehn, Patrick J. Park, Kayla Ferko, Ali R. Khan, and Terry M. Peters

Predicting Alzheimer’s disease progression using multi-modal deep learning approach, Garam Lee, Kwangsik Nho, Byungkon Kang, Kyung Ah Sohn, Dokyoon Kim, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Zaven Khachaturian, Greg Sorensen, Maria Carrillo, Lew Kuller, Marc Raichle, Steven Paul, Peter Davies, Howard Fillit, Franz Hefti, Davie Holtzman, M. Marcel Mesulam, William Potter, Peter Snyder, Tom Montine, and Ronald G. Thomas

Endoscopic Vision Augmentation Using Multiscale Bilateral-Weighted Retinex for Robotic Surgery, Xiongbiao Luo, Hui Qing Zeng, Ying Wan, Xiao Bin Zhang, Yan Ping Du, and Terry M. Peters

Linked MRI signatures of the brain's acute and persistent response to concussion in female varsity rugby players, Kathryn Y. Manning, Alberto Llera, Gregory A. Dekaban, Robert Bartha, Christy Barreira, Arthur Brown, Lisa Fischer, Tatiana Jevremovic, Kevin Blackney, Timothy J. Doherty, Douglas D. Fraser, Jeff Holmes, Christian F. Beckmann, and Ravi S. Menon


Reproducibility of Neurite Orientation Dispersion and Density Imaging (NODDI) in rats at 9.4 Tesla, Patrick McCunn, Kyle M. Gilbert, Peter Zeman, Alex X. Li, Michael J. Strong, Ali R. Khan, and Robert Bartha


Does the Neurological Examination Correlate with Patient-Perceived Outcomes in Degenerative Cervical Myelopathy?, Stuart M.K. McGregor, Sarah A. Detombe, Sandy Goncalves, Patricia Doyle-Pettypiece, Robert Bartha, and Neil Duggal


Synergistic toxicity in an in vivo model of neurodegeneration through the co-expression of human TDP-43M337V and tauT175D protein, Alexander J. Moszczynski, Madeline Harvey, Niveen Fulcher, Cleusa de Oliveira, Patrick McCunn, Neil Donison, Robert Bartha, Susanne Schmid, Michael J. Strong, and Kathryn Volkening

Ultrasound calibration for unique 2.5D conical images, Hareem Nisar, John Moore, Natasha Alves, Germain Hwang, Terry M. Peters, and Elvis C.S. Chen


Detection of active caspase-3 in mouse models of stroke and Alzheimer's disease with a novel dual positron emission tomography/fluorescent tracer [ 68 Ga]Ga-TC3-OGDOTA, Valeriy G. Ostapchenko, Jonatan Snir, Mojmir Suchy, Jue Fan, M. Rebecca Cobb, Blaine A. Chronik, Michael Kovacs, Vania F. Prado, Robert H.E. Hudson, Stephen H. Pasternak, Marco A.M. Prado, and Robert Bartha


Accelerated 129Xe MRI morphometry of terminal airspace enlargement: Feasibility in volunteers and those with alpha-1 antitrypsin deficiency, Alexei Ouriadov, Fumin Guo, David G McCormack, and Grace Parraga


The Canadian Dementia Imaging Protocol: Harmonization validity for morphometry measurements, Olivier Potvin, Isabelle Chouinard, Louis Dieumegarde, Robert Bartha, Pierre Bellec, D. Louis Collins, Maxime Descoteaux, Rick Hoge, Joel Ramirez, Christopher J.M. Scott, Eric E. Smith, Stephen C. Strother, Sandra E. Black, and Simon Duchesne

Functional network resilience to pathology in presymptomatic genetic frontotemporal dementia, Timothy Rittman, Robin Borchert, Simon Jones, John van Swieten, Barbara Borroni, Daniela Galimberti, Mario Masellis, Maria Carmela Tartaglia, Caroline Graff, Fabrizio Tagliavini, Giovanni B. Frisoni, Robert Laforce, Elizabeth Finger, Alexandre Mendonça, Sandro Sorbi, Jonathan D. Rohrer, James B. Rowe, Sónia Afonso, Maria Rosario Almeida, Sarah Anderl-Straub, Christin Andersson, Anna Antonell, Silvana Archetti, Andrea Arighi, Mircea Balasa, Myriam Barandiaran, Nuria Bargalló, Robart Bartha, Benjamin Bender, Luisa Benussi, Valentina Bessi, and Giuliano Binetti


Differential effects of transcranial direct current stimulation on antiphase and inphase motor tasks: A pilot study, Kayla Ryan, Amy L. Schranz, Neil Duggal, and Robert Bartha

Entorhinal cortex volume is associated with dual-task gait cost among older adults with MCI: Results from the gait and brain study, Ryota Sakurai, Robert Bartha, and Manuel Montero-Odasso


Visualization of the Small Airways:What It Is and Why It Matters, Mark L Schiebler and Grace Parraga

Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer’s Dementia, Lucas Porcello Schilling, Tharick A. Pascoal, Eduardo R. Zimmer, Sulantha Mathotaarachchi, Monica Shin, Carlos Roberto de Mello Rieder, Serge Gauthier, André Palmini, Pedro Rosa-Neto, Michael W. Weiner, Paul Aisen, Ronald Petersen, Ronald Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Jeffrey Kaye, Joseph Quinn, Lisa Silbert, Betty Lind, Raina Carter, Sara Dolen, Lon S. Schneider, Sonia Pawluczyk, Mauricio Beccera, Liberty Teodoro, and Bryan M. Spann

Preface, Dinggang Shen, Tianming Liu, Terry M. Peters, Lawrence H. Staib, Caroline Essert, Sean Zhou, Pew Thian Yap, and Ali Khan