Biochemistry Publications
Scientists in the Department of Biochemistry have expertise in genome dynamics, epigenetics, and gene expression; human genetics and clinical biochemistry; signal transduction and intracellular communication; macromolecular structure and dynamics; proteomics; and bioinformatics.
Visit the Department of Biochemistry Research website for additional information,
Submissions from 2023
Selected fermented indigenous vegetables and fruits from Malaysia as potential sources of natural probiotics for improving gut health, Olaide Olawunmi Ajibola, Raymond Thomas, and Babatunde Femi Bakare
Submissions from 2022
Radiation Exposure Determination in a Secure, Cloudbased Online Environment, Ben C. Shirley, Eliseos J. Mucaki, Joan H.M. Knoll, and Peter Rogan
Radiation Exposure Determination in a Secure, Cloud-Based Online Environment, Ben C. Shirley, Eliseos J. Mucaki, and Peter Rogan
Submissions from 2021
Differentially accessible, single copy sequences form contiguous domains along metaphase chromosomes that are conserved among multiple tissues., Seana L Hill, Peter K Rogan, Yi Xuan Wang, and Joan H M Knoll
Radiation Exposure Determination in a Secure, Cloud-based Online Environment, Eliseos J. Mucaki, Ben C. Shirley, and Peter Rogan
Improved radiation expression profiling in blood by sequential application of sensitive and specific gene signatures, Eliseos J. Mucaki, Ben C. Shirley, and Peter K. Rogan
Likely community transmission of COVID-19 infections between neighboring, persistent hotspots in Ontario, Canada [version 1; peer review: awaiting peer review], Elisios J. Mucaki, Ben C. Shirley, and Peter K. Rogan
Gene expression for biodosimetry and effect prediction purposes: promises, pitfalls and future directions - key session ConRad 2021., Patrick Ostheim, Sally A Amundson, Christophe Badie, Dimitry Bazyka, Angela C Evans, Shanaz A Ghandhi, Maria Gomolka, Milagrosa López Riego, Peter K Rogan, Robert Terbrueggen, Gayle E Woloschak, Frederic Zenhausern, Hanns L Kaatsch, Simone Schüle, Reinhard Ullmann, Matthias Port, and Michael Abend
Likely community transmission of COVID-19 infections between neighboring, persistent hotspots in Ontario, Canada, Peter Rogan, Eliseos J. Mucaki, and Ben C. Shirley
Automated Cytogenetic Biodosimetry at Population-Scale., Peter Rogan, Eliseos J. Mucaki, Ben Shirley, Li Yanxin, Ruth Wilkins, Farrah Norton, Olga Sevriukova, Ngoc Duy Pham, Edward Waller, and Joan H.M. Knoll
Likely community transmission of COVID-19 infections between neighboring, persistent hotspots in Ontario, Canada, Ben C. Shirley, Eliseos J. Mucaki, and Peter Rogan
Submissions from 2020
Pathway-extended gene expression signatures integrate novel biomarkers that improve predictions of patient responses to kinase inhibitors, Ashis Jem Bagchee-Clark, Eliseos J. Mucaki, Tyson Whitehead, and Peter Rogan
A proposed molecular mechanism for pathogenesis of severe RNA-viral pulmonary infections, Ashis J. Bagchee-Clark, Eliseos J. Mucaki, Tyson Whitehead, and Peter Rogan
Pathway‐extended gene expression signatures integrate novel biomarkers that improve predictions of patient responses to kinase inhibitors, Ashis Bagchee‐Clark, Eliseos J. Mucaki, Tyson Whitehead, and Peter Rogan
Pathway-extended gene expression signatures integrate novel biomarkers that improve predictions of patient responses to kinase inhibitors, Jem Bagchee-Clark, Eliseos J. Mucaki, Tyson Whitehead, and Peter Rogan
Collaborative, Multidisciplinary Evaluation of Cancer Variants Through Virtual Molecular Tumor Boards Informs Local Clinical Practices., Shruti Rao, Beth Pitel, Alex H Wagner, Simina M Boca, Matthew McCoy, Ian King, Samir Gupta, Ben Ho Park, Jeremy L Warner, James Chen, Peter Rogan, Debyani Chakravarty, Malachi Griffith, Obi L Griffith, and Subha Madhavan
Estimating partial body ionizing radiation exposure by automated cytogenetic biodosimetry, Peter Rogan
Expression Changes Confirm Genomic Variants Predicted to Result in Allele-Specific, Alternative mRNA Splicing, Peter Rogan
Meeting radiation dosimetry capacity requirements of population-scale exposures by geostatistical sampling., Peter K Rogan, Eliseos J Mucaki, Ruipeng Lu, Ben C Shirley, Edward Waller, and Joan H M Knoll
Meeting radiation dosimetry capacity requirements of population-scale exposures by geostatistical sampling., Peter K Rogan, Eliseos J Mucaki, Ruipeng Lu, Ben C Shirley, Edward Waller, and Joan H M Knoll
Estimating partial body ionizing radiation exposure by automated cytogenetic biodosimetry, Ben Shirley and Peter Rogan
Submissions from 2019
Multigene signatures of responses to chemotherapy derived by biochemically-inspired machine learning., Peter K. Rogan
RADIATION DOSE ESTIMATION BY COMPLETELY AUTOMATED INTERPRETATION OF THE DICENTRIC CHROMOSOME ASSAY, Peter Rogan, Yanxin Li, Ben Shirley, Ruth Wilkins, Farrah Norton, and Joan Knoll
Transcription factor binding site clusters identify target genes with similar tissue-wide expression and buffer against mutations., Peter Rogan and Ruipeng Lu
Submissions from 2018
N6-Furfuryladenine is protective in Huntington’s disease models by signaling huntingtin phosphorylation, Laura E. Bowie, Tamara Maiuri, Melanie Alpaugh, Michelle Gabriel, Nicolas Arbez, Danny Galleguillos, Claudia L.K. Hung, Shreya Patel, Jianrun Xia, Nicholas T. Hertz, Christopher A. Ross, David W. Litchfield, Simonetta Sipione, and Ray Truant