Biochemistry Publications

 

Scientists in the Department of Biochemistry have expertise in genome dynamics, epigenetics, and gene expression; human genetics and clinical biochemistry; signal transduction and intracellular communication; macromolecular structure and dynamics; proteomics; and bioinformatics.

Visit the Department of Biochemistry Research website for additional information,

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Submissions from 2015

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Reversing chromatin accessibility differences that distinguish homologous mitotic metaphase chromosomes., Wahab A Khan, Peter K Rogan, and Joan H M Knoll

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Structural Analysis of the 14-3-3ζ/Chibby Interaction Involved in Wnt/β-Catenin Signaling, Ryan C Killoran, Jingsong Fan, Daiwen Yang, Brian H Shilton, and Wing-Yiu Choy

Protein kinase CK2: Systematic relationships with other posttranslational modifications, David W. Litchfield and Laszlo Gyenis

Pin1: Intimate involvement with the regulatory protein kinase networks in the global phosphorylation landscape, David W. Litchfield, Brian H. Shilton, Christopher J. Brandl, and Laszlo Gyenis

FANCM c.5791C>T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity and is a familial breast cancer risk factor, Paolo Peterlongo, Irene Catucci, Mara Colombo, Laura Caleca, Eliseos Mucaki, Massimo Bogliolo, Maria Marin, Francesca Damiola, Loris Bernard, Valeria Pensotti, Sara Volorio, Valentina Dall'Olio, Alfons Meindl, Claus Bartram, Christian Sutter, Harald Surowy, Valérie Sornin, Marie Gabrielle Dondon, Séverine Eon-Marchais, Dominique Stoppa-Lyonnet, Nadine Andrieu, Olga M. Sinilnikova, Gillian Mitchell, Paul A. James, Ella Thompson, Marina Marchetti, Cristina Verzeroli, Carmen Tartari, Gabriele Lorenzo Capone, Anna Laura Putignano, and Maurizio Genuardi

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Characterization of RanBPM Molecular Determinants that Control its Subcellular Localization, Louisa M Salemi, Sandra O Loureiro, and Caroline Schild-Poulter

Differential expression, distinct localization and opposite effect on Golgi structure and cell differentiation by a novel splice variant of human PRMT5, Muhammad Sohail, Manli Zhang, David Litchfield, Lisheng Wang, Sam Kung, and Jiuyong Xie

Noncovalent binding of a cyclic peptide inhibitor to the peptidyl-prolyl isomerase Pin1, explored by hydrogen exchange mass spectrometry, Modupeola A. Sowole, Brendan T. Innes, Mahasilu Amunugama, David W. Litchfield, Christopher J. Brandl, Brian H. Shilton, and Lars Konermann

Systematic investigation of hierarchical phosphorylation by protein kinase CK2, Nicole St-Denis, Michelle Gabriel, Jacob P. Turowec, Gregory B. Gloor, Shawn S.C. Li, Anne Claude Gingras, and David W. Litchfield

Protein Kinases and Caspases: Bidirectional Interactions in Apoptosis, Stephanie A. Zukowski and David W. Litchfield

Submissions from 2014

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Interpretation of mRNA splicing mutations in genetic disease: review of the literature and guidelines for information-theoretical analysis., Natasha Caminsky, Eliseos J Mucaki, and Peter K Rogan

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Splicing mutation analysis reveals previously unrecognized pathways in lymph node-invasive breast cancer., Stephanie N Dorman, Coby Viner, and Peter K Rogan

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Unifying the analysis of high-throughput sequencing datasets: characterizing RNA-seq, 16S rRNA gene sequencing and selective growth experiments by compositional data analysis., Andrew D Fernandes, Jennifer Ns Reid, Jean M Macklaim, Thomas A McMurrough, David R Edgell, and Gregory B Gloor

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Localized, non-random differences in chromatin accessibility between homologous metaphase chromosomes., Wahab A Khan, Peter K Rogan, and Joan Hm Knoll

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Automating dicentric chromosome detection from cytogenetic biodosimetry data., Peter K Rogan, Yanxin Li, Asanka Wickramasinghe, Akila Subasinghe, Natasha Caminsky, Wahab Khan, Jagath Samarabandu, Ruth Wilkins, Farrah Flegal, and Joan H Knoll

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Validation of predicted mRNA splicing mutations using high-throughput transcriptome data., Coby Viner, Stephanie N Dorman, Ben C Shirley, and Peter K Rogan

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Validation of predicted mRNA splicing mutations using high-throughput transcriptome data, Coby Viner, Stephanie Dorman, Ben Shirley, and Peter Rogan

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MegaTevs: Single-Chain Dual Nucleases for Efficient Gene Disruption, Jason M Wolfs, Matthew DaSilva, Sarah E Meister, Xu Wang, Caroline Schild-Poulter, and David R. Edgell

Submissions from 2013

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Individual Interactions of the b Subunits within the Stator of the Escherichia coli ATP Synthase., Karsten Brandt, Sarah Maiwald, Brigitte Herkenhoff-Hesselmann, Kerstin Gnirss, Joerg-Christian Greie, Stanley D Dunn, and Gabriele Deckers-Hebestreit

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Fuzzy complex formation between the intrinsically disordered prothymosin α and the Kelch domain of Keap1 involved in the oxidative stress response., Halema Khan, Elio A Cino, Anne Brickenden, Jingsong Fan, Daiwen Yang, and Wing-Yiu Choy

Submissions from 2012

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Stomatin-like protein 2 deficiency in T cells is associated with altered mitochondrial respiration and defective CD4+ T cell responses., Darah A Christie, Panagiotis Mitsopoulos, Julianna Blagih, Stanley D Dunn, Julie St-Pierre, Russell G Jones, Grant M Hatch, and Joaquín Madrenas

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(1)H, (15)N and (13)C backbone resonance assignments of the Kelch domain of mouse Keap1., Elio Cino, Jingsong Fan, Daiwen Yang, and Wing-Yiu Choy

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Elastic deformations of the rotary double motor of single F(o)F(1)-ATP synthases detected in real time by Förster resonance energy transfer., Stefan Ernst, Monika G Düser, Nawid Zarrabi, Stanley D Dunn, and Michael Börsch

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Elastic deformations of the rotary double motor of single F(o)F(1)-ATP synthases detected in real time by Förster resonance energy transfer., Stefan Ernst, Monika G Düser, Nawid Zarrabi, Stanley D Dunn, and Michael Börsch

A machine learning approach for phenotype name Recognition, Maryam Khordad, Robert E. Mercer, and Peter Rogan