Biochemistry Publications

 

Scientists in the Department of Biochemistry have expertise in genome dynamics, epigenetics, and gene expression; human genetics and clinical biochemistry; signal transduction and intracellular communication; macromolecular structure and dynamics; proteomics; and bioinformatics.

Visit the Department of Biochemistry Research website for additional information,

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Submissions from 2010

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Characterizing Short-Lived Protein Folding Intermediates by Top-Down Hydrogen Exchange Mass Spectrometry, Jingxi Pan, Jun Han, Christoph H. Borchers, and Lars Konermann

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Calcium-Induced Structural Transitions of the Calmodulin−Melittin System Studied by Electrospray Mass Spectrometry: Conformational Subpopulations and Metal-Unsaturated Intermediates, Jingxi Pan and Lars Konermann

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Site-Directed Mutagenesis Combined with Oxidative Methionine Labeling for Probing Structural Transitions of a Membrane Protein by Mass Spectrometry, Yan Pan, Leonid Brown, and Lars Konermann

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Membrane Protein Structural Insights from Chemical Labeling and Mass Spectrometry, Yan Pan and Lars Konermann

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Mipomersen as a Potential Adjunctive Therapy for Hypercholesterolemia, Neeraj Patel and Robert A. Hegele

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Functional Analysis of a Type 1 Parathyroid Hormone Receptor Intracellular Tail Mutant [KRK(484-6)AAA]: Effects on Second Messenger Generation and Cellular Targeting, Eric K. Patterson, Anthony B. Hodsman, Geoffrey N. Hendy, Lucie Canaff, F. Richard Bringhurst, and Laurence J. Fraher

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Enzymatic Site-Specific Functionalization of Protein Methyltransferase Substrates with Alkynes for Click Labeling, Wibke Peters, Sophie Willnow, Mike Duisken, Henning Kleine, Thomas Macherey, Kelly E. Duncan, David W. Litchfield, Bernhard Lüscher, and Elmar Weinhold

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Genetic Variation at the NPC1L1 Gene Locus, Plasma Lipoproteins, and Heart Disease Risk in the Elderly, Eliana Polisecki, Inga Peter, Jason S. Simon, Robert A. Hegele, Michele Robertson, Ian Ford, James Shepherd, Christopher Packard, J. Wouter Jukema, Anton J. M. de Craen, Rudi G. J. Westendorp, Brendan M. Buckley, Ernst J. Schaefer, and Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) Investigators

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Deeper Understanding of Unclassified Intronic Variants and ESEs, Peter K. Rogan

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Usher Syndrome Splicing Variants Evaluated in Nasal Epithelial Cells, Peter K. Rogan

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Facial Diagnosis of Mild and Variant CdLS: Insights from a Dysmorphologist Survey, Sarika Rohatgi, Dinah Clark, Antonie D. Kline, Laird G. Jackson, Juan Pie, Victoria Siu, Feliciano J. Ramos, Ian D. Krantz, and Matthew A. Deardorff

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Tn10/IS10 Transposition Is Downregulated at the Level of Transposase Expression by the RNA-binding Protein Hfq, Joseph A. Ross, Simon J. Wardle, and David B. Haniford

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Differential Interaction of the E3 Ligase Parkin with the Proteasomal Subunit S5a and the Endocytic Protein Eps15, Susan S. Safadi and Gary S. Shaw

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Large-scale Phosphoproteome of Human Whole Saliva Using Disulfide-thiol Interchange Covalent Chromatography and Mass Spectrometry, Erdjan Salih, Walter L. Siqueira, Eva J. Helmerhorst, and Frank G. Oppenheim

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Evidence of Intact Histatins in the in vivo Acquired Enamel Pellicle, W. L. Siqueira, H. C. Margolis, E. J. Helmerhorst, F. M. Mendes, and F. G. Oppenheim

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Amish Microcephaly: Long-term Survival and Biochemical Characterization, Victoria Mok Siu, Suzanne Ratko, Asuri N. Prasad, Chitra Prasad, and C. Anthony Rupar

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Ischemia Dysregulates DNA Methyltransferases and p16(INK4a) Methylation in Human Colorectal Cancer Cells, Karolina Skowronski, Sonam Dubey, David Rodenhiser, and Brenda L. Coomber

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Human 21T Breast Epithelial Cell Lines Mimic Breast Cancer Progression in Vivo and in Vitro and Show Stage-specific Gene Expression Patterns, Lesley H. Souter, Joseph D. Andrews, Guihua Zhang, Amy C. Cook, Carl O. Postenka, Waleed Al-Katib, Hon S. Leong, David I. Rodenhiser, Ann F. Chambers, and Alan B. Tuck

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SH3TC2, a Protein Mutant in Charcot-Marie-Tooth Neuropathy, Links Peripheral Nerve Myelination to Endosomal Recycling, Claudia Stendel, Andreas Roos, Henning Kleine, Estelle Arnaud, Murat Ozçelik, Páris N. M. Sidiropoulos, Jennifer Zenker, Fanny Schüpfer, Ute Lehmann, Radoslaw M. Sobota, David W. Litchfield, Bernhard Lüscher, Roman Chrast, Ueli Suter, and Jan Senderek

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Time-Dependent Changes in Side-Chain Solvent Accessibility during Cytochrome c Folding Probed by Pulsed Oxidative Labeling and Mass Spectrometry, Bradley B. Stocks and Lars Konermann

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Synthesis of MRI Contrast Agents Derived from DOTAM-Gly-L-Phe-OH Incorporating a Disulfide Bridge: Conjugation to a Cell Penetrating Peptide and Preparation of a Dimeric Agent, Mojmír Suchý, Alex X. Li, Robert Bartha, and Robert H. E. Hudson

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A Paramagnetic Chemical Exchange-based MRI Probe Metabolized by Cathepsin D: Design, Synthesis and Cellular Uptake Studies, Mojmír Suchý, Robert Ta, Alex X. Li, Filip Wojciechowski, Stephen H. Pasternak, Robert Bartha, and Robert H. E. Hudson

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Preparing Titania Aerogel Monolithic Chromatography Columns Using Supercritical Carbon Dioxide, Ruohong Sui, Suya Liu, Gilles A. Lajoie, and Paul A. Charpentier

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A G1 Checkpoint Mediated by the Retinoblastoma Protein That Is Dispensable in Terminal Differentiation but Essential for Senescence, Srikanth Talluri, Christian E. Isaac, Mohammad Ahmad, Shauna A. Henley, Sarah M. Francis, Alison L. Martens, Rod Bremner, and Frederick A. Dick

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Controlled Deposition of Highly Oriented Type I Collagen Mimicking In Vivo Collagen Structures, Annabell Tenboll, Behafarid Darvish, Weimin Hou, Anne-Sophie Duwez, S. Jeffrey Dixon, Harvey A. Goldberg, Bernd Grohe, and Silvia Mittler