Biochemistry Publications | Biochemistry Department | Western University

Biochemistry Publications

 

Scientists in the Department of Biochemistry have expertise in genome dynamics, epigenetics, and gene expression; human genetics and clinical biochemistry; signal transduction and intracellular communication; macromolecular structure and dynamics; proteomics; and bioinformatics.

Visit the Department of Biochemistry Research website for additional information,

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Submissions from 2011

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At the Crossroads of Vaginal Health and Disease, the Genome Sequence of Lactobacillus Iners AB-1, Jean M. Macklaim, Gregory B. Gloor, Kingsley C. Anukam, Sarah Cribby, and Gregor Reid

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Histatin 1 Resists Proteolytic Degradation When Adsorbed to Hydroxyapatite, E. E. McDonald, H. A. Goldberg, N. Tabbara, F. M. Mendes, and W. L. Siqueira

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Structural Characterization of Partially Disordered Human Chibby: Insights into Its Function in the Wnt-Signaling Pathway, Sulayman Mokhtarzada, Corey Yu, Anne Brickenden, and Wing-Yiu Choy

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Interaction between CK2α and CK2β, the Subunits of Protein Kinase CK2: Thermodynamic Contributions of Key Residues on the CK2α Surface, Jennifer Raaf, Nils Bischoff, Karsten Klopffleisch, Elena Brunstein, Birgitte B. Olsen, Greg Vilk, David W. Litchfield, Olaf-Georg Issinger, and Karsten Niefind

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Microbiota Restoration: Natural and Supplemented Recovery of Human Microbial Communities, Gregor Reid, Jessica A. Younes, Henny C. Van der Mei, Gregory B. Gloor, Rob Knight, and Henk J. Busscher

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Gene Signatures of Breast Cancer Progression and Metastasis, David I. Rodenhiser, Joseph D. Andrews, Theodore A. Vandenberg, and Ann F. Chambers

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Impact of Autosomal Recessive Juvenile Parkinson's Disease Mutations on the Structure and Interactions of the Parkin Ubiquitin-like Domain, Susan S. Safadi, Kathryn R. Barber, and Gary S. Shaw

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Identification of Regions Responsible for the Open Conformation of S100A10 Using Chimaeric S100A11-S100A10 Proteins, Liliana Santamaria-Kisiel and Gary S. Shaw

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A Regression Framework Incorporating Quantitative and Negative Interaction Data Improves Quantitative Prediction of PDZ Domain-peptide Interaction from Primary Sequence, Xiaojian Shao, Chris S. H. Tan, Courtney Voss, Shawn S. C. Li, Naiyang Deng, and Gary D. Bader

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Association of the Disordered C-terminus of CDC34 with a Catalytically Bound Ubiquitin, Donald E. Spratt and Gary S. Shaw

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Decreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS., Kenrick A Vassall, Helen R Stubbs, Heather A Primmer, Ming Sze Tong, Sarah M Sullivan, Ryan Sobering, Saipraveen Srinivasan, Lee-Ann K Briere, Stanley D Dunn, Wilfredo Colón, and Elizabeth M Meiering

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Hyaluronan Metabolism in Remodeling Extracellular Matrix: Probes for Imaging and Therapy of Breast Cancer, M. Veiseh and E. A. Turley

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Two rotary motors in F-ATP synthase are elastically coupled by a flexible rotor and a stiff stator stalk., André Wächter, Yumin Bi, Stanley D Dunn, Brian D Cain, Hendrik Sielaff, Frank Wintermann, Siegfried Engelbrecht, and Wolfgang Junge

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Retinoic Acid Is a Key Regulatory Switch Determining the Difference between Lung and Thyroid Fates in Xenopus laevis, Jean H. Wang, Steven J. Deimling, Nicole E. D'Alessandro, Lin Zhao, Fred Possmayer, and Thomas A. Drysdale

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Mechanism of Bone Collagen Degradation due to KOH Treatment, C. Wynnyckyj, S. Omelon, T. L. Willett, K. Kyle, H. Goldberg, and M. D. Grynpas

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Structural Basis for c-KIT Inhibition by the Suppressor of Cytokine Signaling 6 (SOCS6) Ubiquitin Ligase, Fahad Zadjali, Ashley C. W. Pike, Mattias Vesterlund, Jianmin Sun, Chenggang Wu, Shawn S. C. Li, Lars Rönnstrand, Stefan Knapp, Alex N. Bullock, and Amilcar Flores-Morales

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Histone Deacetylase Inhibitors SAHA and Sodium Butyrate Block G1-to-S Cell Cycle Progression in Neurosphere Formation by Adult Subventricular Cells, Qiong Zhou, Clifton L Dalgard, Christopher Wynder, and Martin L Doughty

Submissions from 2010

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Site-Specific IGFBP-1 Hyper-Phosphorylation in Fetal Growth Restriction: Clinical and Functional Relevance, Majida Abu Shehab, Javad Khosravi, Victor K. M. Han, Brian H. Shilton, and Madhulika B. Gupta

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Surface Charge of Electrosprayed Water Nanodroplets: A Molecular Dynamics Study, Elias Ahadi and Lars Konermann

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Neuroprotective Mechanism Conferred by 17beta-estradiol on the Biochemical Basis of Alzheimer's Disease, Z. Amtul, L. Wang, D. Westaway, and R. F. Rozmahel

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Multi-Platform Whole-Genome Microarray Analyses Refine the Epigenetic Signature of Breast Cancer Metastasis with Gene Expression and Copy Number, Joseph Andrews, Wendy Kennette, Jenna Pilon, Alexandra Hodgson, Alan B. Tuck, Ann F. Chambers, and David I. Rodenhiser

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Roles of Electrostatics and Conformation in Protein-Crystal Interactions, Paul V. Azzopardi, Jason O'Young, Gilles Lajoie, Mikko Karttunen, Harvey A. Goldberg, and Graeme K. Hunter

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Phosphorylation of Ser136 Is Critical for Potent Bone Sialoprotein-mediated Nucleation of Hydroxyapatite Crystals, Gurpreet S. Baht, Jason O'Young, Antonia Borovina, Hong Chen, Coralee E. Tye, Mikko Karttunen, Gilles A. Lajoie, Graeme K. Hunter, and Harvey A. Goldberg

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Stanniocalcin-1 Regulates Extracellular ATP-Induced Calcium Waves in Human Epithelial Cancer Cells by Stimulating ATP Release from Bystander Cells, Gregory J. Block, Gabriel D. DiMattia, and Darwin J. Prockop

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Polyploidy Impairs Human Aortic Endothelial Cell Function and Is Prevented by Nicotinamide Phosphoribosyltransferase, Nica M. Borradaile and J. Geoffrey Pickering