Biochemistry Publications

 

Scientists in the Department of Biochemistry have expertise in genome dynamics, epigenetics, and gene expression; human genetics and clinical biochemistry; signal transduction and intracellular communication; macromolecular structure and dynamics; proteomics; and bioinformatics.

Visit the Department of Biochemistry Research website for additional information,

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Submissions from 2010

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Advances in Genomic Analysis of Stroke: What Have We Learned and Where Are We Headed?, Matthew B. Lanktree, Martin Dichgans, and Robert A. Hegele

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Phenomics: Expanding the Role of Clinical Evaluation in Genomic Studies, Matthew B. Lanktree, Reina G. Hassell, Piya Lahiry, and Robert A. Hegele

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Extremes of Unexplained Variation as a Phenotype: An Efficient Approach for Genome-Wide Association Studies of Cardiovascular Disease, Matthew B. Lanktree, Robert A. Hegele, Nicholas J. Schork, and J. David Spence

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Genetic Variation in Hyaluronan Metabolism Loci Is Associated with Plasma Plasminogen Activator Inhibitor-1 Concentration, Matthew B. Lanktree, Christopher T. Johansen, Sonia S. Anand, A. Darlene Davis, Ruby Miller, Salim Yusuf, Robert A. Hegele, SHARE, and SHARE-AP Investigators

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A Translational View of the Genetics of Lipodystrophy and Ectopic Fat Deposition, Matthew B. Lanktree, Christopher T. Johansen, Tisha R. Joy, and Robert A. Hegele

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Association of Apolipoprotein B with Incident Type 2 Diabetes in an Aboriginal Canadian Population, Sylvia H. Ley, Stewart B. Harris, Philip W. Connelly, Mary Mamakeesick, Joel Gittelsohn, Thomas M. Wolever, Robert A. Hegele, Bernard Zinman, and Anthony J. Hanley

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Assessing the Association of the HNF1A G319S Variant with C-reactive Protein in Aboriginal Canadians: A Population-based Epidemiological Study, Sylvia H. Ley, Robert A. Hegele, Philip W. Connelly, Stewart B. Harris, Mary Mamakeesick, Henian Cao, Joel Gittelsohn, Ravi Retnakaran, Bernard Zinman, and Anthony J. Hanley

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Nerve Growth Factor Activation of the TrkA Receptor Induces Cell Death, by Macropinocytosis, in Medulloblastoma Daoy Cells, Chunhui Li, James I. S. Macdonald, Todd Hryciw, and Susan O. Meakin

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Systematic Identification of Methyllysine-Driven Interactions for Histone and Nonhistone Targets, Huadong Liu, Marek Galka, Aimee Iberg, Zezhou Wang, Lei Li, Courtney Voss, Xinfeng Jiang, Gilles Lajoie, Zhiping Huang, Mark T. Bedford, and Shawn S. C. Li

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Temtamy Preaxial Brachydactyly Syndrome Is Caused by Loss-of-Function Mutations in Chondroitin Synthase 1, a Potential Target of BMP Signaling, Yun Li, Kathrin Laue, Samia Temtamy, Mona Aglan, L. Damla Kotan, Gökhan Yigit, Husniye Canan, Barbara Pawlik, Gudrun Nürnberg, Emma L. Wakeling, Oliver W. Quarrell, Ingelore Baessmann, Matthew B. Lanktree, Mustafa Yilmaz, Robert A. Hegele, Khalda Amr, Klaus W. May, Peter Nürnberg, A. Kemal Topaloglu, Matthias Hammerschmidt, and Bernd Wollnik

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Independent Mechanisms of Stimulation of Polynucleotide Kinase/Phosphatase by Phosphorylated and Non-phosphorylated XRCC1, Meiling Lu, Rajam S. Mani, Feridoun Karimi-Busheri, Mesfin Fanta, Hailin Wang, David W. Litchfeld, and Michael Weinfeld

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Cerebral Protein Synthesis in the Ovine Fetus Near Term with Amino Acid Infusion and Insulin-Induced Hypoaminoacidemia., James N. Maclachlan, Jeremy D. McCallum, Norman Smith, Brad Matushewski, and Bryan S. Richardson

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Dual Modes of Interaction between XRCC4 and Polynucleotide Kinase/Phosphatase: Implications for Nonhomologous End Joining, Rajam S. Mani, Yaping Yu, Shujuan Fang, Meiling Lu, Mesfin Fanta, Angela E. Zolner, Nasser Tahbaz, Dale A. Ramsden, David W. Litchfield, Susan P. Lees-Miller, and Michael Weinfeld

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Side-by-Side Comparison of Five Commercial Media Systems in a Mouse Model: Suboptimal In Vitro Culture Interferes with Imprint Maintenance, B. A. Market-Velker, A. D. Fernandes, and M. R. W. Mann

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Dual Effects of Superovulation: Loss of Maternal and Paternal Imprinted Methylation in a Dose-dependent Manner, Brenna A. Market-Velker, Liyue Zhang, Lauren S. Magri, Anne C. Bonvissuto, and Mellissa R. W. Mann

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Codon Optimization for Enhanced Escherichia Coli Expression of Human S100A11 and S100A1 Proteins, Nicole M. Marlatt, Donald E. Spratt, and Gary S. Shaw

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The Effects of Oligomerization on Saccharomyces cerevisiae Mcm4/6/7 Function, Xiaoli Ma, Brent E. Stead, Atoosa Rezvanpour, and Megan J. Davey

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Song: I'll Repair for You, Derek T. McLachlin

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Family history of cancer and cancer risks in women with BRCA1 or BRCA2 mutations., Kelly Metcalfe, Jan Lubinski, Henry T. Lynch, Parviz Ghadirian, William D. Foulkes, Charmaine Kim-Sing, Susan Neuhausen, Nadine Tung, Barry Rosen, Jacek Gronwald, Peter Ainsworth, Kevin Sweet, Andrea Eisen, Ping Sun, and Steven A. Narod

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Opposing Regulatory Roles of Phosphorylation and Acetylation in DNA Mispair Processing by Thymine DNA Glycosylase, Ryan D. Mohan, David W. Litchfield, Joseph Torchia, and Marc Tini

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Naringenin Decreases Progression of Atherosclerosis by Improving Dyslipidemia in High-Fat-Fed Low-Density Lipoprotein Receptor-Null Mice, Erin E. Mulvihill, Julia M. Assini, Brian G. Sutherland, Alessandra S. Dimattia, Maryam Khami, Julie B. Koppes, Cynthia G. Sawyez, Stewart C. Whitman, and Murray W. Huff

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Antiatherogenic Properties of Flavonoids: Implications for Cardiovascular Health, Erin E. Mulvihill and Murray W. Huff

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Molecular Mechanisms and Treatment Strategies for Dupuytren's Disease, David B. O'Gorman, Linda Vi, and Bing Siang Gan

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NIP1/DUOXA1 Expression in Epithelial Breast Cancer Cells: Regulation of Cell Adhesion and Actin Dynamics, Elena A. Ostrakhovitch and Shawn S. C. Li

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Does Family History Predict the Age at Onset of New Breast Cancers in BRCA1 and BRCA2 Mutation-positive Families?, S. Panchal, L. Bordeleau, A. Poll, M. Llacuachaqui, O. Shachar, P. Ainsworth, S. Armel, A. Eisen, P. Sun, and S. A. Narod