This collection contains theses and dissertations from the Department of Biomedical Engineering, collected from the Scholarship@Western Electronic Thesis and Dissertation Repository

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Theses/Dissertations from 2022

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A two-layer continuous-capillary oxygen transport model: Development and application to blood flow regulation in resting skeletal muscle., Keith C. Afas

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Large-scale Analysis and Automated Detection of Trunnion Corrosion on Hip Arthroplasty Devices, Anastasia M. Codirenzi

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The Role of Transient Vibration of the Skull on Concussion, Rodrigo Dalvit Carvalho da Silva

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Biomechanical Investigation of Complete and Partial Medial Collateral Ligament Injuries, Callahan Doughty

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Towards A Comprehensive Software Suite for Stereotactic Neurosurgery, Greydon Gilmore

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The Bio-Mechanical Development and Kinematic Evaluation of Zone I and Zone II Injuries and their Corresponding Surgical Repair Techniques using an In-Vitro Active Finger Motion Simulator: A Cadaveric Study, Mohammad Haddara

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Mechanical Evaluation of Gyroid Structures to Combat Orthopaedic Implant Infections, Sydney Hitchon

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The Development of a Motion Sensing Device for Use in a Home Setting, Jaspreet K. Kalsi

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A Novel Ultrasound Elastography Technique for Evaluating Tumor Response to Neoadjuvant Chemotherapy in Patients with Locally Advanced Breast Cancer, Niusha Kheirkhah

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Thermo-responsive Antibiotic-Eluting Coatings for Treating Infection near Orthopedic Implants, Jan Chung Kwan

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Effects of Modulating the Culture Microenvironment on the Growth and Secretome of Human Adipose-Derived Stromal Cells, Zhiyu Liang

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Conducting Polypyrrole Hydrogel Biomaterials For Drug Delivery And Cartilage Tissue Regeneration, Iryna Liubchak

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Motion and Crosslinked Polyethylene Wear in Reverse Total Shoulder Arthroplasty, Christopher Millward

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Intracardiac Ultrasound Guided Systems for Transcatheter Cardiac Interventions, Hareem Nisar

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Investigation of Cell Derived Nanoparticles for Drug Delivery and Osteogenic Differentiation of Human Stem/Stromal Cells, Shruthi Polla Ravi

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Quantitative Image Analysis of White Matter Dysregulation Using Brain Normalization for Diagnostic Analysis of Pediatric Hydrocephalus, Renee-Marie Ragguett

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Automation through Deep-Learning to Quantify Ventilation Defects in Lungs from High-Resolution Isotropic Hyperpolarized 129Xe Magnetic Resonance Imaging, Tuneesh Kaur Ranota

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Early Biological Response of Articular Cartilage to Hemiarthroplasty Wear, Debora Rossetti

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Sol-Gel Derived Bioceramic Poly(Diethyl Fumarate – Co – Triethoxyvinylsilane) Composite, Aref Sleiman

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The Application of Digital Volume Correlation Bone Strain Measurements in the Osteoarthritic Glenohumeral Joint, Jakub R. Targosinski

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Development of Brain-Derived Bioscaffolds for Neural Progenitor Cell Culture and Delivery, Julia Terek

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Modelling and Evaluation of Piezoelectric Actuators for Wearable Neck Rehabilitation Devices, Shaemus D. Tracey

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Investigation on the Performance of Dry Powder Inhalation System for Enhanced Delivery of Levosalbutamol Sulfate, Yuqing Ye

Theses/Dissertations from 2021

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Development of a Wireless Telemetry Load and Displacement Sensor for Orthopaedic Applications, William Anderson

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Organic-Inorganic Hybrid Biomaterials for Bone Tissue Engineering and Drug Delivery, Neda Aslankoohi

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Fabrication Of Inkjet-Printed Enzyme-Based Biosensors Towards Point-Of-Care Applications, Yang Bai

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The Use of CT to Assess Shoulder Kinematics and Measure Glenohumeral Arthrokinematics, Baraa Daher

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The Development of Region-Specific Decellularized Meniscus Bioinks for 3D Bioprinting Applications, Sheradan Doherty

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In Vitro Analyses of the Contributions of the Hip Capsule to Joint Biomechanics, Emma Donnelly

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Long-Circulating, Degradable Lanthanide-Based Contrast Agents for Pre-Clinical Microcomputed Tomography of the Vasculature, Eric Grolman

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Mixed-reality visualization environments to facilitate ultrasound-guided vascular access, Leah Groves

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Diffusion Kurtosis Imaging in Temporal Lobe Epilepsy, Loxlan W. Kasa

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Extracellular Matrix-Derived Microcarriers as 3-D Cell Culture Platforms, Anna Kornmuller

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3D Printed Polypyrrole Scaffolds for pH Dependent Drug Delivery with Applications in Bone Regeneration, Matthew T. Lawrence

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Development of Multifunctional Drug Delivery Systems for Locoregional Therapy, Xinyi Li

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Motion Intention Estimation using sEMG-ACC Sensor Fusion, Jose Alejandro Lopez

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Biomaterial for Cervical Intervertebral Disc Prosthesis, Helium Mak

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Biomechanical Analysis of Ligament Modelling Techniques and Femoral Component Malrotation Following TKA, Liam A. Montgomery

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Snapshot Three-Dimensional Surface Imaging With Multispectral Fringe Projection Profilometry, Parsa Omidi

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4DCT to Examine Carpal Motion, Sydney M. Robinson

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Seizure Detection Using Deep Learning, Information Theoretic Measures and Factor Graphs, Bahareh Salafian

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Modeling Fetal Brain Development: A semi-automated platform for localization, reconstruction, and segmentation of the fetal brain on MRI, Jianan Wang

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Immobilized Jagged1 for Notch3-specific Differentiation and Phenotype Control of Vascular Smooth Muscle Cells, Kathleen E. Zohorsky

Theses/Dissertations from 2020

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Simulation Approaches to X-ray C-Arm-based Interventions, Daniel R. Allen

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Implementing a multi-segment foot model in a clinical setting to measure inter-segmental joint motions, Tahereh Amiri

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Cardiac Modelling Techniques to Predict Future Heart Function and New Biomarkers in Acute Myocardial Infarction, Sergio C. H. Dempsey

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Feasibility of Twisted Coiled Polymer Actuators for Use in Upper Limb Wearable Rehabilitation Devices, Brandon P.R. Edmonds

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Metal Additive Manufacturing for Fixed Dental Prostheses, Mai EL Najjar

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Using an Internal Auditory Stimulus to Activate the Developing Primary Auditory Cortex: A Fetal fMRI Study, Estee Goldberg

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Development of Water-Soluble Polyesters for Tissue Engineering Applications, Trent Gordon

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Development Of Hybrid Coating Materials To Improve The Success Of Titanium Implants, Zach Gouveia

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A 3D Printed Axon-Mimetic Diffusion MRI Phantom, Tristan K. Kuehn

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Development of an Active Infection Monitoring Knee Spacer for Two-Stage Revision, Michael K. Lavdas

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Computational Modeling of the Human Brain for mTBI Prediction and Diagnosis, Yanir Levy

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Pulmonary Imaging of Chronic Obstructive Pulmonary Disease using Multi-Parametric Response Maps, Jonathan MacNeil

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Optimization of Indentation for the Material Characterization of Soft PVA-Cryogels, Md. Mansur ul Mulk

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Development and Validation of Augmented Reality Training Simulator for Ultrasound Guided Percutaneous Renal Access, Yanyu Mu

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A Biomechanical Investigation into the Effect of Experimental Design on Wrist Biomechanics and Contact Mechanics, Clare E. Padmore

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Structure-Function Relationships in the Brain: Applications in Neurosurgery, Daiana-Roxana Pur

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The Effect of Joint Alignment After a Wrist Injury on Joint Mechanics and Osteoarthritis Development, Puneet Kaur Ranota

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Development and Validation of Tools for Improving Intraoperative Implant Assessment with Ultrasound during Gynaecological Brachytherapy, Jessica Robin Rodgers

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Studies on Carbon Quantum Dots with Special Luminescent Properties and Their Capability of Overcoming the Biological Barriers, Ji Su Song

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Machine Learning towards General Medical Image Segmentation, Clara Tam

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The Migration and Wear of Reverse Total Shoulder Arthroplasty, Madeleine L. Van de Kleut

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Video Processing for the Evaluation of Vascular Dynamics in Neurovascular Interventions, Reid Vassallo

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Preparation of Intra-articular Drug Delivery Systems for the Treatment of Osteoarthritis, Ian Villamagna

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Deep Reinforcement Learning in Medical Object Detection and Segmentation, Dong Zhang

Theses/Dissertations from 2019

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Fabrication and Characterization of Collagen-Polypyrrole Constructs Using Direct-Ink Write Additive Manufacturing, Rooshan Arshad

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Development of a Force-Based Ream Vector Measurement System For Glenoid Reaming Simulation, David Axford

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Investigation of Visual Perceptions in Parkinson's Disease and the Development of Disease Monitoring Software, Matthew Bernardinis

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Tissue Equivalent Gellan Gum Gel Materials for Clinical MRI and Radiation Dosimetry, Pawel Brzozowski

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Implementation of User-Independent Hand Gesture Recognition Classification Models Using IMU and EMG-based Sensor Fusion Techniques, José Guillermo Collí Alfaro

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Scaffold Design Considerations for Soft Tissue Regeneration, Madeleine M. Di Gregorio

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Remote Navigation and Contact-Force Control of Radiofrequency Ablation Catheters, Daniel Gelman

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High-throughput Fabrication of Drug-loaded Core-shell Tablets with Adjustable Release Profiles from Surface-erodible and Photocrosslinkable Polyanhydrides, Armin Geraili Nejadfomeshi

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Apply dry powder on drug loading and enteric coating of esomeprazole magnesium trihydrate beads and capsules, Xiaojing Ge

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Bioluminescence resonance energy transfer (BRET) - based nanostructured biosensor for detection of glucose, Eugene Hwang

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A Heterogeneous Patient-Specific Biomechanical Model of the Lung for Tumor Motion Compensation and Effective Lung Radiation Therapy Planning, Parya Jafari

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The Co-Delivery of Syngeneic Adipose-Derived Stromal Cells and Macrophages on Decellularized Adipose Tissue Bioscaffolds for In Vivo Soft Tissue Regeneration, Hisham A. Kamoun

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Improving Material Mapping in Glenohumeral Finite Element Models: A Multi-Level Evaluation, Nikolas K. Knowles

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Ultra-High Field Magnetic Resonance Imaging for Stereotactic Neurosurgery, Jonathan Lau

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Formation of a Vascular Regenerative Microenvironment Within Implantable Human Decellularized Adipose Tissue Bioscaffolds, Christopher Leclerc

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Effect of histatin- and statherin-derived engineered salivary peptides on Streptococcus mutans adhesion and on enamel demineralization provoked by cariogenic biofilms, Lina Maria Marin

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Individual Variability of Functional Connectivity in Resting-State and Naturalistic fMRI Paradigms, Mark O'Reilly

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Assessing the Impact of Collared versus Collarless Stems on Implant Migration, Patient Activity and Patient Function Following Total Hip Arthroplasty: A Randomized Clinical Trial, Maxwell E. Perelgut

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Haptics-enabled, GPU augmented surgical simulation platform for glenoid reaming, Vlad Popa

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A Framework for Evaluating Cortical Architectural Anomalies in Temporal Lobe Epilepsy Patients, Hossein Rajali

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Evaluation of Individual Finger Forces During Activities of Daily Living In Healthy Individuals and Those with Hand Arthritis, Michael Riddle

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Design of cell-instructive biomaterial scaffolds for intervertebral disc regeneration, Nadia Sharma

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Finite Element Analysis of Hollow-stemmed Shoulder Implants in Different Bone Qualities Derived from a Statistical Shape and Density Model, Pendar Soltanmohammadi

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A Novel Method for In Vivo Evaluation of Finger Kinematics for Analysis of Activities of Daily Living, Ahmed M. Tanashi

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A structured-light surface scanning system to evaluate breast morphology in standing and supine positions, Olivia Tong

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A Wearable Mechatronic Device for Hand Tremor Monitoring and Suppression: Development and Evaluation, Yue Zhou

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A pH-sensitive Delivery System for the Prevention of Dental Caries Using Salivary Proteins, Yi Zhu

Theses/Dissertations from 2018

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Augmented Reality Ultrasound Guidance in Anesthesiology, Golafsoun Ameri

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Engineering Graphene Oxide-based Nanostructures for DNA sensors, Aditya Balaji

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The Kinematic and Biomechanical Effects of Bracing on the Rehabilitation of the LCL Injured Elbow, Sara M. Banayan

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Development and Assessment of a Micro-CT Based System for Quantifying Loaded Knee Joint Kinematics and Tissue Mechanics, Alexandra M. Blokker

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Process Analytics from Passive Acoustic Emissions Monitoring during Fluidized Bed Pellet Coating in Pharmaceutical Manufacturing, Allan Carter

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A Composite Material-based Computational Model for Diaphragm Muscle Biomechanical Simulation, Brett Coelho