Thesis Format
Integrated Article
Degree
Master of Science
Program
Biomedical Engineering
Supervisor
Peters, Terry
2nd Supervisor
Chen, Elvis
Co-Supervisor
Abstract
Mobile C-Arm systems have enabled interventional spine procedures, such as facet joint injections, to be performed minimally-invasively under X-ray or fluoroscopy guidance. The downside to these procedures is the radiation exposure the patient and medical staff are subject to, which can vary greatly depending on the procedure as well as the skill and experience of the team. Standard training methods for these procedures involve the use of a physical C-Arm with real X-rays training on either cadavers or via an apprenticeship-based program. Many guidance systems have been proposed in the literature which aim to reduce the amount of radiation exposure intraoperatively by supplementing the X-ray images with digitally reconstructed radiographs (DRRs). These systems have shown promising results in the lab but have proven difficult to integrate into the clinical workflow due to costly equipment, safety protocols, and difficulties in maintaining patient registration. Another approach for reducing the amount of radiation exposure is by providing better hands-on training for C-Arm positioning through a pre-operative simulator. Such simulators have been proposed in the literature but still require access to a physical C-Arm or costly tracking equipment. With the goal of providing hands-on, accessible training for C-Arm positioning tasks, we have developed a miniature 3D-printed C-Arm simulator using accelerometer-based tracking. The system is comprised of a software application to interface with the accelerometers and provide a real-time DRR display based on the position of the C-Arm source. We conducted a user study, consisting of control and experimental groups, to evaluate the efficacy of the system as a training tool. The experimental group achieved significantly lower procedure time and higher positioning accuracy than the control group. The system was evaluated positively for its use in medical education via a 5-pt likert scale questionnaire. C-Arm positioning tasks are associated with a highly visual learning-based nature due to the spatial mapping required from 2D fluoroscopic image to 3D C-Arm and patient. Due to the limited physical interaction required, this task is well suited for training in Virtual Reality (VR), eliminating the need for a physical C-Arm. To this end, we extended the system presented in chapter 2 to an entirely virtual-based approach. We implemented the system as a 3DSlicer module and conducted a pilot study for preliminary evaluation. The reception was overall positive, with users expressing enthusiasm towards training in VR, but also highlighting limitations and potential areas of improvement of the system.
Summary for Lay Audience
Mobile X-ray imaging systems (C-Arms) are used in minimally-invasive procedures. Procedures such as facet joint or epidural steroid injections require the clinician to accurately guide the needle to the appropriate anatomical location. Because the clinician is unable to directly see the region they are directing the needle towards, they require X-ray imaging for guidance. Positioning the C-Arm accurately is a difficult task and can often induce excess radiation exposure to the clinician and patient. Extensive training for C-Arm positioning is critical for a successful procedure, but the current standard of training must be limited due to the harmful X-ray exposure to the trainee.
In order to provide a radiation-free solution for training, we have developed two C-Arm simulators. This first is a miniature 3D-printed C-Arm simulator which tracks the position of the X-ray source using cost-effective accelerometers and generates simulated X-ray images in real-time. The second is a Virtual Reality simulator using a scale C-Arm and the HTC Vive Pro for visualization. These simulators enable hands-on training for C-Arm procedures without exposure to ionizing radiation. We evaluated the miniature version via a user study consisting of medical residents. For the evaluation component, The users trained on our simulator performed significantly better than the control group. The VR simulator was evaluated positively for its use in medical education, however a followup study will need to be conducted for more conclusive results.
Recommended Citation
Allen, Daniel R., "Simulation Approaches to X-ray C-Arm-based Interventions" (2020). Electronic Thesis and Dissertation Repository. 7231.
https://ir.lib.uwo.ca/etd/7231
Multimedia Format
youtube
Included in
Bioimaging and Biomedical Optics Commons, Graphics and Human Computer Interfaces Commons, Systems and Integrative Engineering Commons