Research in Medical Biophysics Publications focuses on the application of physics in the human body and those of higher animals while examining topics such as blood flow, orthopedic mechanics, medical imaging and cancer biology. Research is conducted in partnership with clinicians at state-of-the-art facilities located at Western University, London Regional Cancer Program, Lawson Health Research Institute, Robarts Research Institute, and the London Health Sciences Centre.

Visit the Department of Medical Biophysics website for additional information.

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Submissions from 2010

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Imaging of lung function using hyperpolarized helium-3 magnetic resonance imaging: Review of current and emerging translational methods and applications, Sean Fain, Mark L Schiebler, David G McCormack, and Grace Parraga

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Rapid in Vivo Whole Body Composition of Rats Using Cone Beam µCT, Patrick V. Granton, Chris J. D. Norley, Joseph Umoh, Eva A. Turley, Bruce C. Frier, Earl G. Noble, and David W. Holdsworth

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In Vivo Detection of PARACEST Agents with Relaxation Correction, Craig K. Jones, Alex X. Li, Mojmír Suchý, Robert H. E. Hudson, Ravi S. Menon, and Robert Bartha

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Chronic obstructive pulmonary disease: Longitudinal hyperpolarized (3)He MR imaging, Miranda Kirby, Lindsay Mathew, Andrew Wheatley, Giles E Santyr, David G McCormack, and Grace Parraga

Detection of longitudinal lung structural and functional changes after diagnosis of radiation-induced lung injury using hyperpolarized 3He magnetic resonance imaging, Lindsay Mathew, Stewart Gaede, Andrew Wheatley, Roya Etemad-Rezai, George B Rodrigues, and Grace Parraga

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Molecular Mechanisms and Treatment Strategies for Dupuytren's Disease, David B. O'Gorman, Linda Vi, and Bing Siang Gan

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Dietary intervention to reverse carotid atherosclerosis, Iris Shai, J David Spence, Dan Schwarzfuchs, Yaakov Henkin, Grace Parraga, Assaf Rudich, Aaron Fenster, Christiane Mallett, Noah Liel-Cohen, Amir Tirosh, Arkady Bolotin, Joachim Thiery, Georg Martin Fiedler, Matthias Blüher, Michael Stumvoll, and Meir J Stampfer

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A Paramagnetic Chemical Exchange-based MRI Probe Metabolized by Cathepsin D: Design, Synthesis and Cellular Uptake Studies, Mojmír Suchý, Robert Ta, Alex X. Li, Filip Wojciechowski, Stephen H. Pasternak, Robert Bartha, and Robert H. E. Hudson

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A Review of Autoimmune Diseases Associated with Cancer, Patricia Tai, Edward Yu, Kurian Joseph, and Thomas Miale

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D-dimensional Bose Gases and the Lambert W Function, J. Tanguay, M. Gil, D. J. Jeffrey, and S. R. Valluri

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Fused Whole-Heart Coronary and Myocardial Scar Imaging Using 3-T CMR: Implications for Planning of Cardiac Resynchronization Therapy and Coronary Revascularization, James A. White, Nowell Fine, Lorne J. Gula, Raymond Yee, Mohammed Al-Admawi, Qi Zhang, Andrew Krahn, Allan Skanes, Anna MacDonald, Terry Peters, and Maria Drangova

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What Are the Factors that Predict Outcome at Relapse after Previous Esophagectomy and Adjuvant Therapy in High-risk Esophageal Cancer?, Edward Yu, P. Tai, R. Malthaner, L. Stitt, G. Rodrigues, R. Dar, B. Yaremko, J. Younus, M. Sanatani, M. Vincent, B. Dingle, D. Fortin, and R. Inculet

Submissions from 2009

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NAD+, Sirtuins, and Cardiovascular Disease, Nica M. Borradaile and J. Geoffrey Pickering

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Nicotinamide Phosphoribosyltransferase Imparts Human Endothelial Cells with Extended Replicative Lifespan and Enhanced Angiogenic Capacity in a High Glucose Environment, Nica M. Borradaile and J. Geoffrey Pickering

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A Fully Automated Non-external Marker 4D-CT Sorting Algorithm Using a Serial Cine Scanning Protocol, Greg Carnes, Stewart Gaede, Edward Yu, Jake Van Dyk, Jerry Battista, and Ting-Yim Lee

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Analysis of carotid lumen surface morphology using three-dimensional ultrasound imaging, Bernard Chiu, Vadim Beletsky, J David Spence, Grace Parraga, and Aaron Fenster

New and current clinical imaging techniques to study chronic obstructive pulmonary disease, Harvey O Coxson, John Mayo, Stephen Lam, Giles Santyr, Grace Parraga, and Don D Sin

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Cardiac MR Elastography: Comparison with Left Ventricular Pressure Measurement, Thomas Elgeti, Michael Laule, Nikola Kaufels, Jorg Schnorr, Bernd Hamm, Abbas Samani, Jurgen Braun, and Ingolf Sack

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The Management of Thymoma: A Systematic Review and Practice Guideline, Conrad B. Falkson, Andrea Bezjak, Gail Darling, Richard Gregg, Richard Malthaner, Donna E. Maziak, Edward Yu, Christopher A. Smith, Sheila McNair, Yee C. Ung, William K. Evans, and Lung Cancer Disease Site Group of Cancer Care Ontario's Program in Evidence-Based Care

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Lipid Incorporation Inhibits Src-Dependent Assembly of Fibronectin and Type I Collagen by Vascular Smooth Muscle Cells, Matthew J. Frontini, Caroline O'Neil, Cynthia Sawyez, Bosco M. C. Chan, Murray W. Huff, and J. Geoffrey Pickering

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The Use of CT Density Changes at Internal Tissue Interfaces to Correlate Internal Organ Motion with an External Surrogate, Stewart Gaede, Gregory Carnes, Edward Yu, Jake Van Dyk, Jerry Battista, and Ting-Yim Lee

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SIRT1 Markedly Extends Replicative Lifespan if the NAD+ Salvage Pathway Is Enhanced, Cynthia Ho, Eric van der Veer, Oula Akawi, and J. Geoffrey Pickering

Magnetic resonance imaging and three-dimensional ultrasound of carotid atherosclerosis: Mapping regional differences, Adam Krasinski, Bernard Chiu, Aaron Fenster, and Grace Parraga

Three-dimensional ultrasound quantification of intensive statin treatment of carotid atherosclerosis, Adam Krasinski, Bernard Chiu, J David Spence, Aaron Fenster, and Grace Parraga

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Is Hemorrhage in Acute Reperfused Myocardial Infarction a New Marker for the Severity of Tissue Injury?, Andreas Kumar, Jordin D. Green, Jane M. Sykes, Andrea Mitchell, Gerald Wisenberg, and Matthias G. Friedrich