Magnetic resonance imaging and three-dimensional ultrasound of carotid atherosclerosis: Mapping regional differences

Document Type

Article

Publication Date

4-1-2009

Journal

Journal of Magnetic Resonance Imaging : JMRI

Volume

29

Issue

4

First Page

901

Last Page

908

URL with Digital Object Identifier

https://doi.org/10.1002/jmri.21709

Abstract

PURPOSE: To evaluate differences in carotid atherosclerosis measured using magnetic resonance imaging (MRI) and three-dimensional ultrasound (3DUS).

MATERIALS AND METHODS: Ten subject volunteers underwent carotid 3DUS and MRI (multislice black blood fast spin echo, T1-weighted contrast, double inversion recovery, 0.5 mm in-plane resolution, 2 mm slice, 3.0 T) within 1 hour. 3DUS and MR images were manually segmented by two observers providing vessel wall and lumen contours for quantification of vessel wall volume (VWV) and generation of carotid thickness maps.

RESULTS: MRI VWV (1040 +/- 210 mm(3)) and 3DUS VWV (540 +/- 110 mm(3)) were significantly different (P < 0.0001). When normalized for the estimated adventitia volume, mean MRI VWV decreased 240 +/- 50 mm(3) and was significantly different from 3DUS VWV (P < 0.001). Two-dimensional carotid maps showed qualitative evidence of regional differences in the plaque and vessel wall thickness between MR and 3DUS in all subjects. Power Doppler US confirmed that heterogeneity in the common carotid artery in all patients resulted from apparent flow disturbances, not atherosclerotic plaque.

CONCLUSION: MRI and 3DUS VWV were significantly different and carotid maps showed homogeneous thickness differences and heterogeneity in specific regions of interest identified as MR flow artifacts in the common carotid artery.

Notes

This is the peer reviewed version of the following article: A Krasinski, B Chiu, A Fenster & G Parraga (2009). Magnetic resonance imaging and three-dimensional ultrasound of carotid atherosclerosis: Mapping regional differences, 29(4): 901-908, which has been published in final form at https://doi.org/10.1002/jmri.21709. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.

Creative Commons License

Creative Commons Attribution-Noncommercial 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License

This document is currently not available here.

Find in your library

Share

COinS