Research in Medical Biophysics Publications focuses on the application of physics in the human body and those of higher animals while examining topics such as blood flow, orthopedic mechanics, medical imaging and cancer biology. Research is conducted in partnership with clinicians at state-of-the-art facilities located at Western University, London Regional Cancer Program, Lawson Health Research Institute, Robarts Research Institute, and the London Health Sciences Centre.

Visit the Department of Medical Biophysics website for additional information.

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Submissions from 2013

Pulmonary functional imaging using hyperpolarized noble gas MRI: six years of start-up experience at a single site, Miranda Kirby and Grace Parraga

Pulmonary ventilation visualized using hyperpolarized helium-3 and xenon-129 magnetic resonance imaging: Differences in COPD and relationship to emphysema, Miranda Kirby, Sarah Svenningsen, Nikhil Kanhere, Amir Owrangi, Andrew Wheatley, Harvey O Coxson, Giles E Santyr, Nigel A M Paterson, David G McCormack, and Grace Parraga

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One, two and three-dimensional ultrasound measurements of carotid atherosclerosis before and after cardiac rehabilitation: preliminary results of a randomized controlled trial., Tamas J Lindenmaier, Daniel N Buchanan, Damien Pike, Tim Hartley, Robert D Reid, J David Spence, Richard Chan, Michael Sharma, Peter L Prior, Neville Suskin, and Grace Parraga

Lung morphometry using hyperpolarized (129) Xe apparent diffusion coefficient anisotropy in chronic obstructive pulmonary disease, Alexei Ouriadov, Adam Farag, Miranda Kirby, David G McCormack, Grace Parraga, and Giles E Santyr

Semi-automated scoring of pulmonary emphysema from X-ray CT: Trainee reproducibility and accuracy, Amir M Owrangi, Brandon Entwistle, Andrew Lu, Jack Chiu, Nabil Hussain, Roya Etemad-Rezai, and Grace Parraga

Computed tomography density histogram analysis to evaluate pulmonary emphysema in ex-smokers, Amir M Owrangi, Roya Etemad-Rezai, David G McCormack, Ian A Cunningham, and Grace Parraga

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Chronic obstructive pulmonary disease: More imaging, more phenotyping...better care?, Damien Pike and Grace Parraga

Hyperpolarized (3) He and (129) Xe MRI: Differences in asthma before bronchodilation, Sarah Svenningsen, Miranda Kirby, Danielle Starr, Del Leary, Andrew Wheatley, Geoffrey N Maksym, David G McCormack, and Grace Parraga

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A magnetic-resonance-imaging-compatible remote catheter navigation system., Mohammad Ali Tavallaei, Yogesh Thakur, Syed Haider, and Maria Drangova

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Three-dimensional segmentation of three-dimensional ultrasound carotid atherosclerosis using sparse field level sets., E Ukwatta, J Yuan, D Buchanan, B Chiu, J Awad, W Qiu, G Parraga, and A Fenster

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Progression of carotid plaque volume predicts cardiovascular events, Thapat Wannarong, Grace Parraga, Daniel Buchanan, Aaron Fenster, Andrew A House, Daniel G Hackam, and J David Spence

Submissions from 2012

Three-dimensional lung tumor segmentation from x-ray computed tomography using sparse field active models, Joseph Awad, Amir Owrangi, Lauren Villemaire, Elaine O'Riordan, Grace Parraga, and Aaron Fenster

The relationship of carotid three-dimensional ultrasound vessel wall volume with age and sex: comparison to carotid intima-media thickness, Daniel N Buchanan, Tamas Lindenmaier, Shayna McKay, Yves Bureau, Daniel G Hackam, Aaron Fenster, and Grace Parraga

Regional pulmonary response to a methacholine challenge using hyperpolarized (3)He magnetic resonance imaging, Stephen Costella, Miranda Kirby, Geoffrey N Maksym, David G McCormack, Nigel A M Paterson, and Grace Parraga

Hyperpolarized 3He magnetic resonance functional imaging semiautomated segmentation, Miranda Kirby, Mohammadreza Heydarian, Sarah Svenningsen, Andrew Wheatley, David G McCormack, Roya Etemad-Rezai, and Grace Parraga

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Evaluating bronchodilator effects in chronic obstructive pulmonary disease using diffusion-weighted hyperpolarized helium-3 magnetic resonance imaging, Miranda Kirby, Mohammadreza Heydarian, Andrew Wheatley, David G McCormack, and Grace Parraga

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Evidence of adult lung growth in humans., Miranda Kirby, David G McCormack, and Grace Parraga

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Hyperpolarized 3He and 129Xe MR imaging in healthy volunteers and patients with chronic obstructive pulmonary disease, Miranda Kirby, Sarah Svenningsen, Amir Owrangi, Andrew Wheatley, Adam Farag, Alexei Ouriadov, Giles E Santyr, Roya Etemad-Rezai, Harvey O Coxson, David G McCormack, and Grace Parraga

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Modeling stochastic and spatial heterogeneity in a human airway tree to determine variation in respiratory system resistance, Del Leary, Swati A Bhatawadekar, Grace Parraga, and Geoffrey N Maksym

Four-dimensional x-ray computed tomography and hyperpolarized 3He magnetic resonance imaging of gas distribution in lung cancer, L Mathew, R Castillo, E Castillo, B Yaremko, G Rodrigues, R Etemad-Rezai, T Guerrero, and G Parraga

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Hyperpolarized 3He functional magnetic resonance imaging of bronchoscopic airway bypass in chronic obstructive pulmonary disease., Lindsay Mathew, Miranda Kirby, Donald Farquhar, Christopher Licskai, Giles Santyr, Roya Etemad-Rezai, Grace Parraga, and David G McCormack

Hyperpolarized (3)He pulmonary functional magnetic resonance imaging prior to radiation therapy, Lindsay Mathew, Jake Vandyk, Roya Etemad-Rezai, George Rodrigues, and Grace Parraga

Hyperpolarized (3)He magnetic resonance imaging: Comparison with four-dimensional x-ray computed tomography imaging in lung cancer, Lindsay Mathew, Andrew Wheatley, Richard Castillo, Edward Castillo, George Rodrigues, Thomas Guerrero, and Grace Parraga

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Chest MRI in children: Why bother?, Amir M Owrangi and Grace Parraga

Hyperpolarized 129Xe magnetic resonance imaging: Tolerability in healthy volunteers and subjects with pulmonary disease, Yajur Shukla, Andrew Wheatley, Miranda Kirby, Sarah Svenningsen, Adam Farag, Giles E Santyr, Nigel A M Paterson, David G McCormack, and Grace Parraga