Physiology and Pharmacology Publications
Excelling in the study of biological processes on a cellular-molecular and integrative-systemic level and drugs impact on these processes, Research in Physiology and Pharmacology Publications also looks at cardiovascular sciences, cell development and cancer, reproductive biology and endocrinology, and neuroscience.
Visit the Department of Physiology and Pharmacology website for additional information.
Submissions from 2011
Neutrophil elastase acts as a biased agonist for proteinase-activated receptor-2 (PAR 2), Rithwik Ramachandran, Koichiro Mihara, Hyunjae Chung, Bernard Renaux, Chang S. Lau, Daniel A. Muruve, Kathryn A. DeFea, Michel Bouvier, and Morley D. Hollenberg
P2 Receptor Expression, Signaling and Function in Osteoclasts, Juan P. Reyes, Stephen M. Sims, and S. Jeffrey Dixon
Implantation serine proteinase 1 exhibits mixed substrate specificity that silences signaling via proteinase-activated receptors, Navneet Sharma, Rajeev Kumar, Bernard Renaux, Mahmoud Saifeddine, Sandra Nishikawa, Koichiro Mihara, Rithwik Ramachandran, Morley D. Hollenberg, and Derrick E. Rancourt
Stuttered Swallowing: Electric Stimulation of the Right Insula Interferes with Water Swallowing. A Case Report, Peter Sörös, Faisal Al-Otaibi, Savio W. H. Wong, J. Kevin Shoemaker, Seyed M. Mirsattari, Vladimir Hachinski, and Ruth E. Martin
Face Inversion Reduces the Persistence of Global Form and Its Neural Correlates, Lars Strother, Pavagada S. Mathuranath, Adrian Aldcroft, Cheryl Lavell, Melvyn A. Goodale, and Tutis Vilis
Osteopontin Signals through Calcium and Nuclear Factor of Activated T Cells (NFAT) in Osteoclasts: A Novel RGD-dependent Pathway Promoting Cell Survival, Natsuko Tanabe, Benjamin D. Wheal, Jiyun Kwon, Hong H. Chen, Ryan P. P. Shugg, Stephen M. Sims, Harvey A. Goldberg, and S. Jeffrey Dixon
GPR54 (KISS1R) Transactivates EGFR to Promote Breast Cancer Cell Invasiveness, Mateusz Zajac, Jeffrey Law, Dragana Donna Cvetkovic, Macarena Pampillo, Lindsay McColl, Cynthia Pape, Gianni M. Di Guglielmo, Lynne M. Postovit, Andy V. Babwah, and Moshmi Bhattacharya
Submissions from 2010
Polyploidy Impairs Human Aortic Endothelial Cell Function and Is Prevented by Nicotinamide Phosphoribosyltransferase, Nica M. Borradaile and J. Geoffrey Pickering
Modification of Polymer Networks with Bone Sialoprotein Promotes Cell Attachment and Spreading, Wailen D. Chan, Harvey A. Goldberg, Graeme K. Hunter, S. J. Dixon, and Amin S. Rizkalla
The Modulation of TRPM7 Currents by Nafamostat Mesilate Depends Directly upon Extracellular Concentrations of Divalent Cations, Xuanmao Chen, Tomohiro Numata, Minghua Li, Yasuo Mori, Beverley A. Orser, Michael F. Jackson, Zhi-Gang Xiong, and John F. MacDonald
IL-6 and TNFalpha across the Umbilical Circulation in Term Pregnancies: Relationship with Labour Events, Greg Duncombe, Ruud A. W. Veldhuizen, Robert J. Gratton, Victor K. M. Han, and Bryan S. Richardson
Injury Analyses in Rural Children: Comparison of Old-Order Anabaptists and Non-Anabaptists, Karen Forward, Melissa Chan, Tanya Charyk-Stewart, Jason Gilliland, Craig Campbell, and Douglas D. Fraser
Optical Waveguides Formed by Silver Ion Exchange in Schott SG11 Glass for Waveguide Evanescent Field Fluorescence Microscopy: Evanescent Images of HEK293 Cells, Abdollah Hassanzadeh, Michael Nitsche, Souzan Armstrong, S. Jeffrey Dixon, Noushin Nabavi, Rene Harrison, Uwe Langbein, and Silvia Mittler
Increased Blood Pressure and Hyperdynamic Cardiovascular Responses in Carriers of a Common Hyperfunctional Variant of Adenylyl Cyclase 6, Gary J. Hodges, Robert Gros, Robert A. Hegele, Stan Van Uum, J. Kevin Shoemaker, and Ross D. Feldman
Insulin modulates protease-activated receptor 2 signaling: Implications for the innate immune response, Eric Hyun, Rithwik Ramachandran, Nicolas Cenac, Steeve Houle, Perrine Rousset, Amit Saxena, Roland S. Liblau, Morley D. Hollenberg, and Nathalie Vergnolle
EBP1 Is a Novel E2F Target Gene Regulated by Transforming Growth Factor-β, David Judah, Wing Y. Chang, and Lina Dagnino
Mammalian Numb-interacting Protein 1/Dual Oxidase Maturation Factor 1 Directs Neuronal Fate in Stem Cells, Karen A. M. Kennedy, Elena A. Ostrakhovitch, Shelley D. E. Sandiford, Thamara Dayarathna, Xiaojun Xie, Elaine Y. L. Waese, Wing Y. Chang, Qingping Feng, Ilona S. Skerjanc, William L. Stanford, and Shawn S. C. Li
Lysophosphatidic Acid Signals through Multiple Receptors in Osteoclasts to Elevate Cytosolic Calcium Concentration, Evoke Retraction, and Promote Cell Survival, Danielle M. Lapierre, Natsuko Tanabe, Alexey Pereverzev, Martha Spencer, Ryan P. P. Shugg, S. Jeffrey Dixon, and Stephen M. Sims
Towards an Anti-fibrotic Therapy for Scleroderma: Targeting Myofibroblast Differentiation and Recruitment, Andrew Leask
Cross-modal Plasticity in Specific Auditory Cortices Underlies Visual Compensations in the Deaf, Stephen G. Lomber, M. Alex Meredith, and Andrej Kral
Rapid and Direct Transport of Cell Surface APP to the Lysosome Defines a Novel Selective Pathway, Angela Lorenzen, Jonathan Samosh, Kenneth Vandewark, Pieter H. Anborgh, Claudia Seah, Ana C. Magalhaes, Sean P. Cregan, Stephen S. G. Ferguson, and Stephen H. Pasternak
Cerebral Protein Synthesis in the Ovine Fetus Near Term with Amino Acid Infusion and Insulin-Induced Hypoaminoacidemia., James N. Maclachlan, Jeremy D. McCallum, Norman Smith, Brad Matushewski, and Bryan S. Richardson
Kindled Seizure in the Prefrontal Cortex Activated Behavioral Hyperactivity and Increase in Accumbens Gamma Oscillations through the Hippocampus, Jingyi Ma and L. Stan Leung
Opposing Regulatory Roles of Phosphorylation and Acetylation in DNA Mispair Processing by Thymine DNA Glycosylase, Ryan D. Mohan, David W. Litchfield, Joseph Torchia, and Marc Tini
Pyk2 uncouples metabotropic glutamate receptor G protein signaling but facilitates ERK1/2 activation., Alexander A. Nicodemo, Macarena Pampillo, Lucimar T. Ferreira, Lianne B. Dale, Tamara Cregan, Fabiola M. Ribeiro, and Stephen S. G. Ferguson