Physiology and Pharmacology Publications
Excelling in the study of biological processes on a cellular-molecular and integrative-systemic level and drugs impact on these processes, Research in Physiology and Pharmacology Publications also looks at cardiovascular sciences, cell development and cancer, reproductive biology and endocrinology, and neuroscience.
Visit the Department of Physiology and Pharmacology website for additional information.
Submissions from 2008
Proteinases and signalling: Pathophysiological and therapeutic implications via PARs and more, R. Ramachandran and M. D. Hollenberg
Identification of differentially expressed genes in fibroblasts derived from patients with Dupuytren's Contracture, Latha Satish, William A. LaFramboise, David B. O'Gorman, Sandra Johnson, Benjamin Janto, Bing Siang Gan, Mark E. Baratz, Fen Z. Hu, J. Christopher Post, Garth D. Ehrlich, and Sandeep Kathju
Activities enjoyed by patients with dementia together with their spouses and psychological morbidity in carers, R. Searson, A. M. Hendry, R. Ramachandran, A. Burns, and N. Purandare
Biochemical Analysis of Arginine Methylation in Transcription, Marc Tini, Hina Naeem, and Joseph Torchia
The PI3K Pathway Regulates Endochondral Bone Growth through Control of Hypertrophic Chondrocyte Differentiation, Veronica Ulici, Katie D. Hoenselaar, J. Ryan Gillespie, and Frank Beier
Connexin Expression and Gap Junctional Coupling in Human Cumulus Cells: Contribution to Embryo Quality, Hong-Xing Wang, Dan Tong, Faraj El-Gehani, Francis R. Tekpetey, and Gerald M. Kidder
Submissions from 2007
C-type Natriuretic Peptide Regulates Endochondral Bone Growth through p38 MAP Kinase-dependent and – Independent Pathways, Hanga Agoston, Sameena Khan, Claudine G. James, J. Ryan Gillespie, Rosa Serra, Lee-Anne Stanton, and Frank Beier
Forced Mobilization Accelerates Pathogenesis: Characterization of a Preclinical Surgical Model of Osteoarthritis, C Thomas G. Appleton, David D. McErlain, Vasek Pitelka, Neil Schwartz, Suzanne M. Bernier, James L. Henry, David W. Holdsworth, and Frank Beier
Activation of Transcription Factors by Extracellular Nucleotides in Immune and Related Cell Types, Souzan Armstrong, Jasminka Korcok, Stephen M. Sims, and S. Jeffrey Dixon
Analysis of a Missense Variant of the Human N-formyl Peptide Receptor that Is Associated with Agonist-independent β-arrestin Association and Indices of Inflammation, M. Bhattacharya, J. Wang, F. M. Ribeiro, S. J. Dixon, R. D. Feldman, R. A. Hegele, and S. S. G. Ferguson
Src Kinase Inhibition Promotes the Chondrocyte Phenotype, Laura Bursell, Anita Woods, Claudine G. James, Daphne Pala, Andrew Leask, and Frank Beier
Mouse Preimplantation Embryo Responses to Culture Medium Osmolarity Include Increased Expression of CCM2 and p38 MAPK Activation, Barry Fong, Patricia H. Watson, and Andrew J. Watson
Effects of Vitaxin®, a Novel Therapeutic in Trial for Metastatic Bone Tumors, on Osteoclast Functions in Vitro, Azza Gramoun, Seema Shorey, Jill D. Bashutski, S. Jeffrey Dixon, Stephen M. Sims, Johan N. M. Heersche, and Morris F. Manolson
Expression Profiling of Dexamethasone-treated Primary Chondrocytes Identifies Targets of Glucocorticoid Signalling in Endochondral Bone Development, Claudine G. James, Veronica Ulici, Jan Tuckermann, T. Michael Underhill, and Frank Beier
Erythropoietin Improves Skeletal Muscle Microcirculation and Tissue Bioenergetics in a Mouse Sepsis Model, Raymond Kao, Anargyros Xenocostas, Tao Rui, Pei Yu, Weixiong Huang, James Rose, and Claudio M. Martin
P2Y Nucleotide Receptor Signaling through MAPK/ERK Is Regulated by Extracellular Matrix: Involvement of β3 Integrins, Julie C. Kudirka, Nattapon Panupinthu, Mark A. Tesseyman, S. Jeffrey Dixon, and Suzanne M. Bernier
P2X7 Nucleotide Receptors Mediate Blebbing in Osteoblasts through a Pathway Involving Lysophosphatidic Acid, Nattapon Panupinthu, Lin Zhao, Fred Possmayer, Hua Z. Ke, Stephen M. Sims, and S. Jeffrey Dixon
Inflammatory mediators modulate thrombin and cathepsin-G signaling in human bronchial fibroblasts by inducing expression of proteinase-activated receptor-4, Rithwik Ramachandran, Laura R. Sadofsky, Yupei Xiao, Andrew Botham, Michael Cowen, Alyn H. Morice, and Steven J. Compton
Proteinase-activated receptor-2 activating peptides: Distinct canine coronary artery receptor systems, Mahmoud Saifeddine, Michelle L. Seymour, Yu Pei Xiao, Steven J. Compton, Steeve Houle, Rithwik Ramachandran, Wallace K. MacNaughton, Serge Simonet, Christine Vayssettes-Courchay, Tony J. Verbeuren, and Morley D. Hollenberg
Submissions from 2006
Dexamethasone stimulates expression of C-type Natriuretic Peptide in chondrocytes, Hanga Agoston, Laurie Baybayan, and Frank Beier
Bacterial Superantigens Bypass Lck-Dependent T Cell Receptor Signaling by Activating a Gα11-Dependent, PLC-β-Mediated Pathway, Clara Bueno, Caitlin D. Lemke, Gabriel Criado, Miren L. Baroja, Stephen S. G. Ferguson, A. K. M. Nur-Ur Rahman, Constantine D. Tsoukas, John K. McCormick, and Joaquin Madrenas
The Transcription Factor ATF3 is Upregulated During Chondrocyte Differentiation and Represses Cyclin D1 and A Gene Transcription, Claudine G. James, Anita Woods, T. Michael Underhill, and Frank Beier
Regulation of Cancer Cell Migration and Bone Metastasis by RANKL, D. Holstead Jones, Tomoki Nakashima, Otto H. Sanchez, Ivona Kozieradzki, Svetlana V. Komarova, Ildiko Sarosi, Sean Morony, Evelyn Rubin, Renu Sarao, Carlo V. Hojilla, Vukoslav Komnenovic, Young-Yun Kong, Martin Schreiber, S. Jeffrey Dixon, Stephen M. Sims, Rama Khokha, Teiji Wada, and Josef M. Penninger
Scar Wars: Is TGFβ the Phantom Menace in Scleroderma?, Andrew Leask
Women and Pharmacologic Therapy in Rural and Remote Canada, Beverly D. Leipert, Doreen Matsui, and Michael J. Rieder