Physiology and Pharmacology Publications

 

Excelling in the study of biological processes on a cellular-molecular and integrative-systemic level and drugs impact on these processes, Research in Physiology and Pharmacology Publications also looks at cardiovascular sciences, cell development and cancer, reproductive biology and endocrinology, and neuroscience.

Visit the Department of Physiology and Pharmacology website for additional information.

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Submissions from 2006

Proteinase-activated receptor2 agonists upregulate granulocyte colony-stimulating factor, IL-8, and VCAM-1 expression in human bronchial fibroblasts, Rithwik Ramachandran, Alyn H. Morice, and Steven J. Compton

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Up-regulation of Endogenous RGS2 Mediates Cross-desensitization between Gs and Gq Signaling in Osteoblasts, Anju Anne Roy, Caroline Nunn, Hong Ming, Min-Xu Zou, Josef Penninger, Lorrie A. Kirshenbaum, S. Jeffrey Dixon, and Peter Chidiac

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Antioxidant Effect of Zinc and Zinc-metallothionein in the Acute Cytotoxicity of Hydrogen Peroxide in Ehrlich Ascites Tumour Cells, Zacharias E. Suntres and Edmund M. K. Lui

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Prooxidative Effect of Copper-metallothionein in the Acute Cytotoxicity of Hydrogen Peroxide in Ehrlich Ascites Tumour Cells, Zacharias E. Suntres and Edmund M. K. Lui

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Viable Group A Streptococci in Macrophages during Acute Soft Tissue Infection, Pontus Thulin, Linda Johansson, Donald E. Low, Bing S. Gan, Malak Kotb, Allison McGeer, and Anna Norrby-Teglund

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The Induction of CCN2 by TGFbeta1 Involves Ets-1, Jonathan P. Van Beek, Laura Kennedy, Jason S. Rockel, Suzanne M. Bernier, and Andrew Leask

Submissions from 2005

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A Novel Mass Spectrometry-based Assay for GSK-3β Activity, Erin Bowley, Erin Mulvihill, Jeffrey C. Howard, Brian J. Pak, Bing Siang Gan, and David B. O'Gorman

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Sicily Statement on Evidence-based Practice, Martin Dawes, William Summerskill, Paul Glasziou, Antonino Cartabellotta, Janet Martin, Kevork Hopayian, Franz Porzsolt, Amanda Burls, and James Osborne

Characterization of a novel protein from Proatheris superciliaris venom: Proatherocytin, a 34-kDa platelet receptor PAR1 agonist, Gavin D. Laing, Steven J. Compton, Rithwik Ramachandran, Gemma L.J. Fuller, Mark C. Wilkinson, Simon C. Wagstaff, Stephen P. Watson, Aura S. Kamiguti, R. David G. Theakston, and Yotis A. Senis

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Influence of Age and Gender of Healthy Adults on Scoring Patterns on the Community Balance and Mobility Scale, Rohini Rocque, Doreen Bartlett, Janet Brown, and S. Jayne Garland

Submissions from 2004

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Enhanced Dupuytren's Disease Fibroblast Populated Collagen Lattice Contraction is Independent of Endogenous Active TGF-beta2, Raymond Tse, Jeffrey Howard, Yan Wu, and Bing Siang Gan

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Antioxidant Protection from HIV-1 gp120-induced Neuroglial Toxicity, Kimberley A. Walsh, Joseph F. Megyesi, John X. Wilson, Jeff Crukley, Victor E. Laubach, and Robert R. Hammond

Submissions from 2003

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Responsiveness of Bovine Cumulus-Oocyte-Complexes (COC) to Porcine and Recombinant Human FSH, and the Effect of COC Quality on Gonadotropin Receptor and Cx43 Marker Gene mRNAs During Maturation In Vitro, Michele D. Calder, Anita N. Caveney, Lawrence C. Smith, and Andrew J. Watson

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Elevated Levels of β-catenin and Fibronectin in Three-dimensional Collagen Cultures of Dupuytren's Disease Cells are Regulated by Tension in Vitro, Jeffrey C. Howard, Vincenzo M. Varallo, Douglas C. Ross, James H. Roth, Kenneth J. Faber, Benjamin Alman, and Bing Siang Gan

Submissions from 2001

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Inhibition of Cytokine Production and Interference in IL-2 Receptor-mediated Jak-Stat Signaling by the Hydroxylamine Metabolite of Sulfamethoxazole, David A. Hess, Erin F. O'Leary, James T. Lee, Wassim Y. Almawi, Joaquin Madrenas, and Michael J. Rieder

Submissions from 2000

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P2 Purinergic Receptors on Osteoblasts and Osteoclasts: Potential Targets for Drug Development, S. Jeffrey Dixon and Stephen M. Sims

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HDL-cholesterol-raising Effect of Orange Juice in Subjects with Hypercholesterolemia, Elzbieta M. Kurowska, J. David Spence, John Jordan, Stephen Wetmore, David J. Freeman, Leonard A. Piché, and Paula Serratore

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Identification of a Novel Mechanism for Endotoxin-mediated Down-modulation of CC Chemokine Receptor Expression, Luoling Xu, Masud H. Khandaker, Jana Barlic, Longsi Ran, Miren L. Borja, Joaquín Madrenas, Rahbar Rahimpour, Kong Chen, Gordon Mitchell, Christopher M. Tan, Mark DeVries, Ross D. Feldman, and David J. Kelvin

Submissions from 1999

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Variation in Red Cell Transfusion Practice in the Intensive Care Unit: A Multicentre Cohort Study, Paul C. Hébert, George Wells, Claudio Martin, Martin Tweeddale, John Marshall, Morris Blajchman, Giuseppe Pagliarello, Dean Sandham, Irwin Schweitzer, Denis Boisvert, and Lisa Calder

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Cytotoxicity of Sulfonamide Reactive Metabolites: Apoptosis and Selective Toxicity of CD8(+) Cells by the Hydroxylamine of Sulfamethoxazole, David A. Hess, Margaret E. Sisson, Hamza Suria, John Wijsman, Ram Puvanesasingham, Joaquín Madrenas, and Michael J. Rieder

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Metalloproteinases Are Involved in Lipopolysaccharide- and Tumor Necrosis Factor-alpha-mediated Regulation of CXCR1 and CXCR2 Chemokine Receptor Expression, Masud H. Khandaker, Gordon Mitchell, Luoling Xu, Joseph D. Andrews, Rajkumari Singh, Harry Leung, Joaquín Madrenas, Stephen S. G. Ferguson, Ross D. Feldman, and David J. Kelvin

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CD45 Modulation of CXCR1 and CXCR2 in Human Polymorphonuclear Leukocytes, Gordon B. Mitchell, Masud H. Khandaker, Rahbar Rahimpour, Luoling Xu, Andrew I. Lazarovits, J. Geoffrey Pickering, Hamza Suria, Joaquín Madrenas, David K. Pomerantz, Ross D. Feldman, and David J. Kelvin