Physiology and Pharmacology Publications

 

Excelling in the study of biological processes on a cellular-molecular and integrative-systemic level and drugs impact on these processes, Research in Physiology and Pharmacology Publications also looks at cardiovascular sciences, cell development and cancer, reproductive biology and endocrinology, and neuroscience.

Visit the Department of Physiology and Pharmacology website for additional information.

Follow


Submissions from 2012

Link

Long Telomeres Bypass the Requirement for Telomere Maintenance in Human Tumorigenesis, Michael A. S. Taboski, David C. F. Sealey, Jennifer Dorrens, Chandrakant Tayade, Dean H. Betts, and Lea Harrington

Activation of immobility-related hippocampal theta by cholinergic septohippocampal neurons during vestibular stimulation., Siew Kian Tai, Jingyi Ma, Klaus-Peter Ossenkopp, and L Stan Leung

Long-lasting auditory gating deficit accompanied by GABA(B) receptor dysfunction in the hippocampus after early-life limbic seizures in rats., Min-Lan Tsai, Melanie Crutchley, Richard Boyce, Jingyi Ma, Francis Boon, D Peter Cain, and L Stan Leung

Submissions from 2011

Structure, function and pathophysiology of protease activated receptors, Mark N. Adams, Rithwik Ramachandran, Mei Kwan Yau, Jacky Y. Suen, David P. Fairlie, Morley D. Hollenberg, and John D. Hooper

Link

The Yin and Yang Actions of North American Ginseng Root in Modulating the Immune Function of Macrophages, Chike Godwin Azike, Paul Abrahams Charpentier, Jirui Hou, Hua Pei, and Edmund Man King Lui

Link

The Role of Vision in Detecting and Correcting Fingertip Force Errors during Object Lifting, Gavin Buckingham, Nathalie S. Ranger, and Melvyn A. Goodale

Link

Thrombospondin 1 Is a Key Mediator of Transforming Growth Factor β-mediated Cell Contractility in Systemic Sclerosis via a Mitogen-activated Protein Kinase Kinase (MEK)/Extracellular Signal-regulated Kinase (ERK)-dependent Mechanism, Yunliang Chen, Andrew Leask, David J. Abraham, Laura Kennedy, Shi-wen Xu, Christopher P. Denton, Carol M. Black, Liaquat S. Verjee, and Mark Eastwood

Link

Regulation of the BRCA1 Gene by an SRC3/53BP1 Complex, Dale Corkery, Gobi Thillainadesan, Niamh Coughlan, Ryan D. Mohan, Majdina Isovic, Marc Tini, and Joseph Torchia

Link

The Increased In Vitro Osteoclastogenesis in Patients with Rheumatoid Arthritis Is due to Increased Percentage of Precursors and Decreased Apoptosis — The In Vitro Osteoclast Differentiation in Arthritis (IODA) Study, M. Durand, G. Boire, S. V. Komarova, S. J. Dixon, S. M. Sims, R. E. Harrison, N. Nabavi, O. Maria, M. F. Manolson, M. Mizianty, L. Kurgan, and A. J. de Brum-Fernandes

PDF

Analysis of Oocyte-Like Cells Differentiated from Porcine Fetal Skin-Derived Stem Cells, Paul W. Dyce, Wei Shen, Evanna Huynh, Hua Shao, Daniel A. F. Villagómez, Gerald M. Kidder, W. Allan King, and Julang Li

Link

Stanniocalcin 2 Alters PERK Signalling and Reduces Cellular Injury during Cerulein Induced Pancreatitis in Mice, Elena N. Fazio, Gabriel E. Dimattia, Sami A. Chadi, Kristin D. Kernohan, and Christopher L. Pin

The active Zot domain (aa 288-293) increases ZO-1 and myosin 1C serine/threonine phosphorylation, alters interaction between ZO-1 and its binding partners, and induces tight junction disassembly through proteinase activated receptor 2 activation, Simeon E. Goldblum, Usha Rai, Amit Tripathi, Manjusha Thakar, Luigina De Leo, Nicola Di Toro, Tarcisio Not, Rithwik Ramachandran, Adam C. Puche, Morley D. Hollenberg, and Alessio Fasano

Link

Male Reproductive System Defects and Subfertility in a Mutant Mouse Model of Oculodentodigital Dysplasia, M. Gregory, C. N. Kahiri, K. J. Barr, C. E. Smith, L. Hermo, D. G. Cyr, and Gerald M. Kidder

Link

Mechanical Tension Increases CCN2/CTGF Expression and Proliferation in Gingival Fibroblasts via a TGFβ-Dependent Mechanism, Fen Guo, David E. Carter, and Andrew Leask

Link

Elimination of the Vesicular Acetylcholine Transporter in the Striatum Reveals Regulation of Behaviour by Cholinergic-Glutamatergic Co-Transmission, Monica S. Guzman, Xavier De Jaeger, Sanda Raulic, Ivana A. Souza, Alex X. Li, Susanne Schmid, Ravi S. Menon, Raul R. Gainetdinov, Marc G. Caron, Robert Bartha, Vania F. Prado, and Marco A. M. Prado

Resting-state networks in the macaque at 7 T., R Matthew Hutchison, L Stan Leung, Seyed M Mirsattari, Joseph S Gati, Ravi S Menon, and Stefan Everling

Mechanisms behind the anti-inflammatory actions of insulin, Eric Hyun, Rithwik Ramachandran, Morley D. Hollenberg, and Nathalie Vergnolle

A model of intracellular θ phase precession dependent on intrinsic subthreshold membrane currents., L Stan Leung

PDF

A model of intracellular θ phase precession dependent on intrinsic subthreshold membrane currents., L Stan Leung

PDF

Lesion of cholinergic neurons in nucleus basalis enhances response to general anesthetics, Leung L. Stan

Link

mPGES-1 Null Mice Are Resistant to Bleomycin-induced Skin Fibrosis, Matthew R. McCann, Roxana Monemdjou, Parisa Ghassemi-Kakroodi, Hassan Fahmi, Gemma Perez, Shangxi Liu, Xu Shi-Wen, Sunil K Parapuram, Fumiaki Kojima, Christopher P Denton, David J Abraham, Johanne Martel-Pelletier, Leslie J Crofford, Andrew Leask, and Mohit Kapoor

Link

Thrombospondin 1 in Hypoxia-conditioned Media Blocks the Growth of Human Microvascular Endothelial Cells and Is Increased in Systemic Sclerosis Tissues, Luke Morgan-Rowe, Joanna Nikitorowicz, Xu Shiwen, Andrew Leask, Janice Tsui, David Abraham, and Richard Stratton

Neutrophil elastase acts as a biased agonist for proteinase-activated receptor-2 (PAR 2), Rithwik Ramachandran, Koichiro Mihara, Hyunjae Chung, Bernard Renaux, Chang S. Lau, Daniel A. Muruve, Kathryn A. DeFea, Michel Bouvier, and Morley D. Hollenberg

Link

P2 Receptor Expression, Signaling and Function in Osteoclasts, Juan P. Reyes, Stephen M. Sims, and S. Jeffrey Dixon

Implantation serine proteinase 1 exhibits mixed substrate specificity that silences signaling via proteinase-activated receptors, Navneet Sharma, Rajeev Kumar, Bernard Renaux, Mahmoud Saifeddine, Sandra Nishikawa, Koichiro Mihara, Rithwik Ramachandran, Morley D. Hollenberg, and Derrick E. Rancourt