Physiology and Pharmacology Publications

 

Excelling in the study of biological processes on a cellular-molecular and integrative-systemic level and drugs impact on these processes, Research in Physiology and Pharmacology Publications also looks at cardiovascular sciences, cell development and cancer, reproductive biology and endocrinology, and neuroscience.

Visit the Department of Physiology and Pharmacology website for additional information.

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Submissions from 2018

Monitoring joint blood flow with DCE TR-NIRS to assess treatment response in rheumatoid arthritis, Seva Ioussoufovitch, Laura B. Morrison, Lise Desjardins, Jennifer A. Hadway, Keith St Lawrence, Ting Yim Lee, Frank Beier, and Mamadou Diop

A quadrantic bias in prefrontal representation of visual-mnemonic space, Matthew L. Leavitt, Florian Pieper, Adam J. Sachs, and Julio C. Martinez-Trujillo

Dissecting Modulatory Effects of Visual Attention in Primate Lateral Prefrontal Cortex Using Signal Detection Theory, Julio Martinez-Trujillo and Roberto Adamo Gulli

Inactivation of hepatic ATRX in Atrx Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxine, Megan E. Rowland, Yan Jiang, Frank Beier, and Nathalie G. Bérubé

Submissions from 2017

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview, Stephen P.H. Alexander, Eamonn Kelly, Neil V. Marrion, John A. Peters, Elena Faccenda, Simon D. Harding, Adam J. Pawson, Joanna L. Sharman, Christopher Southan, O. Peter Buneman, John A. Cidlowski, Arthur Christopoulos, Anthony P. Davenport, Doriano Fabbro, Michael Spedding, Jörg Striessnig, and Jamie A. Davies

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview, Stephen P.H. Alexander, Eamonn Kelly, Neil V. Marrion, John A. Peters, Elena Faccenda, Simon D. Harding, Adam J. Pawson, Joanna L. Sharman, Christopher Southan, O. Peter Buneman, John A. Cidlowski, Arthur Christopoulos, Anthony P. Davenport, Doriano Fabbro, Michael Spedding, Jörg Striessnig, and Jamie A. Davies

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Maternal nicotine exposure leads to decreased cardiac protein disulfide isomerase and impaired mitochondrial function in male rat offspring., Nicole G Barra, Maria Lisyansky, Taylor A Vanduzer, Sandeep Raha, Alison C Holloway, and Daniel B Hardy

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G protein-coupled KISS1 receptor is overexpressed in triple negative breast cancer and promotes drug resistance., Alexandra Blake, Magdalena Dragan, Rommel G Tirona, Daniel B Hardy, Muriel Brackstone, Alan B Tuck, Andy V Babwah, and Moshmi Bhattacharya

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Increased incidence of non-alcoholic fatty liver disease in male rat offspring exposed to fluoxetine during fetal and neonatal life involves the NLRP3 inflammasome and augmented de novo hepatic lipogenesis., Nicole E De Long, Daniel B Hardy, Noelle Ma, and Alison C Holloway

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Resting state functional network disruptions in a kainic acid model of temporal lobe epilepsy., Ravnoor Singh Gill, Seyed M Mirsattari, and L Stan Leung

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Maternal Undernutrition and Long-term Effects on Hepatic Function, Daniel B. Hardy

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Perinatal Malnutrition and Epigenetic Regulation of Long-term Metabolism in the Liver and Adipose Tissue, Daniel B. Hardy

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Developmental origins of health and disease: current knowledge and potential mechanisms, Daniel J. Hoffman, Rebecca M. Reynolds, and Daniel B. Hardy

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Effects of Protein Deficiency on Perinatal and Postnatal Health Outcomes, Shelby L. Oke and Daniel B. Hardy

Cockroach allergen serine proteinases: Isolation, sequencing and signalling via proteinase-activated receptor-2, D. J. Polley, K. Mihara, R. Ramachandran, H. Vliagoftis, B. Renaux, M. Saifeddine, M. O. Daines, S. Boitano, and M. D. Hollenberg

Targeting a proteinase-activated receptor 4 (PAR4) carboxyl terminal motif to regulate platelet function, Rithwik Ramachandran, Koichiro Mihara, Pierre Thibeault, Christina M. Vanderboor, Björn Petri, Mahmoud Saifeddine, Michel Bouvier, and Morley D. Hollenberg

Submissions from 2016

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Associative spike timing-dependent potentiation of the basal dendritic excitatory synapses in the hippocampus in vivo., Thomas K Fung, Clayton S Law, and L Stan Leung

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Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer., James B Greenaway, Carl Virtanen, Kata Osz, Tamas Revay, Daniel Hardy, Trevor Shepherd, Gabriel DiMattia, and Jim Petrik

Natural-Product-Derived Transient Receptor Potential Melastatin 8 (TRPM8) Channel Modulators, Christina M. Legay, Evgueni Gorobets, Mircea Iftinca, Rithwik Ramachandran, Christophe Altier, and Darren J. Derksen

Thrombin-mediated direct activation of proteinase-activated Receptor-2: Another target for thrombin signaling, Koichiro Mihara, Rithwik Ramachandran, Mahmoud Saifeddine, Kristina K. Hansen, Bernard Renaux, Danny Polley, Stacy Gibson, Christina Vanderboor, and Morley D. Hollenberg

Proteinases, their extracellular targets, and inflammatory signaling, Rithwik Ramachandran, Christophe Altier, Katerina Oikonomopoulou, and Morley D. Hollenberg

Submissions from 2015

Reduction in disease progression by inhibition of transforming growth factor α-CCL2 signaling in experimental posttraumatic osteoarthritis, C. Thomas G. Appleton, Shirine E. Usmani, Michael A. Pest, Vasek Pitelka, John S. Mort, and Frank Beier

Neuroinflammation-induced interactions between protease-activated receptor 1 and proprotein convertases in HIV-associated neurocognitive disorder, Woo Jin Kim, Erin Zekas, Robert Lodge, Delia Susan-Resiga, Edwidge Marcinkiewicz, Rachid Essalmani, Koichiro Mihara, Rithwik Ramachandran, Eugene Asahchop, Benjamin Gelman, Éric A. Cohen, Christopher Power, Morley D. Hollenberg, and Nabil G. Seidah

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Proteomic Signature of the Murine Intervertebral Disc, Matthew R. McCann

Novel Insights into Osteoarthritis Joint Pathology from Studies in Mice, Paxton M. Moon and Frank Beier