Physiology and Pharmacology Publications
Excelling in the study of biological processes on a cellular-molecular and integrative-systemic level and drugs impact on these processes, Research in Physiology and Pharmacology Publications also looks at cardiovascular sciences, cell development and cancer, reproductive biology and endocrinology, and neuroscience.
Visit the Department of Physiology and Pharmacology website for additional information.
Submissions from 2017
Targeting a proteinase-activated receptor 4 (PAR4) carboxyl terminal motif to regulate platelet function, Rithwik Ramachandran, Koichiro Mihara, Pierre Thibeault, Christina M. Vanderboor, Björn Petri, Mahmoud Saifeddine, Michel Bouvier, and Morley D. Hollenberg
Submissions from 2016
Gene Expression Microarray Data from Human Microvascular Endothelial Cells Supplemented with a Low Concentration of Niacin, Nica M. Borradaile and Jennifer M. Hughes-Large
Associative spike timing-dependent potentiation of the basal dendritic excitatory synapses in the hippocampus in vivo., Thomas K Fung, Clayton S Law, and L Stan Leung
Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer., James B Greenaway, Carl Virtanen, Kata Osz, Tamas Revay, Daniel Hardy, Trevor Shepherd, Gabriel DiMattia, and Jim Petrik
Nicotine Directly Induces Endoplasmic Reticulum Stress Response in Rat Placental Trophoblast Giant Cells, Daniel B. Hardy
Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer, Daniel B. Hardy
Natural-Product-Derived Transient Receptor Potential Melastatin 8 (TRPM8) Channel Modulators, Christina M. Legay, Evgueni Gorobets, Mircea Iftinca, Rithwik Ramachandran, Christophe Altier, and Darren J. Derksen
Positive allosteric modulator of GABAB receptor alters behavioral effects but not afterdischarge progression induced by partial hippocampal kindling., L Stan Leung, Miao Jin, Liangwei Chu, and Jingyi Ma
Effects of hippocampal partial kindling on sensory and sensorimotor gating and methamphetamine-induced locomotion in kindling-prone and kindling-resistant rats., Jingyi Ma and L Stan Leung
Thrombin-mediated direct activation of proteinase-activated Receptor-2: Another target for thrombin signaling, Koichiro Mihara, Rithwik Ramachandran, Mahmoud Saifeddine, Kristina K. Hansen, Bernard Renaux, Danny Polley, Stacy Gibson, Christina Vanderboor, and Morley D. Hollenberg
Proteinases, their extracellular targets, and inflammatory signaling, Rithwik Ramachandran, Christophe Altier, Katerina Oikonomopoulou, and Morley D. Hollenberg
Nicotine Directly Induces Endoplasmic Reticulum Stress Response in Rat Placental Trophoblast Giant Cells, Michael K. Wong, Alison Holloway C, and Daniel B. Hardy
Submissions from 2015
Reduction in disease progression by inhibition of transforming growth factor α-CCL2 signaling in experimental posttraumatic osteoarthritis, C. Thomas G. Appleton, Shirine E. Usmani, Michael A. Pest, Vasek Pitelka, John S. Mort, and Frank Beier
Adverse Effects of Perinatal Nicotine Exposure on Reproductive Outcomes, Daniel B. Hardy and Michael K. Wong
Neuroinflammation-induced interactions between protease-activated receptor 1 and proprotein convertases in HIV-associated neurocognitive disorder, Woo Jin Kim, Erin Zekas, Robert Lodge, Delia Susan-Resiga, Edwidge Marcinkiewicz, Rachid Essalmani, Koichiro Mihara, Rithwik Ramachandran, Eugene Asahchop, Benjamin Gelman, Éric A. Cohen, Christopher Power, Morley D. Hollenberg, and Nabil G. Seidah
Proteomic Signature of the Murine Intervertebral Disc, Matthew R. McCann
Novel Insights into Osteoarthritis Joint Pathology from Studies in Mice, Paxton M. Moon and Frank Beier
Deletion of dual specificity phosphatase 1 does not predispose mice to increased spontaneous osteoarthritis, Michael Andrew Pest, Courtney Alice Pest, Melina Rodrigues Bellini, Qingping Feng, and Frank Beier
GPCR-mediated EGF receptor transactivation regulates TRPV4 action in the vasculature, Mahmoud Saifeddine, Mahmoud El-Daly, Koichiro Mihara, Nigel W. Bunnett, Peter McIntyre, Christophe Altier, Morley D. Hollenberg, and Rithwik Ramachandran
HIGHER HEPATIC MIR-29 EXPRESSION IN UNDERNOURISHED MALE RATS DURING THE POSTNATAL PERIOD TARGETS THE LONG-TERM REPRESSION OF INSULIN-LIKE GROWTH FACTOR 1, Gurjeev Sohi, Andrew Revesz, Julie Ramkumar, and Daniel B. Hardy
Maternal Nicotine Exposure Leads to Impaired Disulfide Bond Formation and Augmented Endoplasmic Reticulum Stress in the Rat Placenta, Michael Wong, Catherine J. Nicholson, Alison C. Holloway, and Daniwl Hardy
Submissions from 2014
Proteinase-activated receptors 1 and 2 and the regulation of porcine coronary artery contractility: A role for distinct tyrosine kinase pathways, Mahmoud El-Daly, Mahmoud Saifeddine, Koichiro Mihara, Rithwik Ramachandran, Christopher R. Triggle, and Morley D. Hollenberg
Mouse models of osteoarthritis: Modelling risk factors and assessing outcomes, Hang Fang and Frank Beier
Loss of the mammalian DREAM complex deregulates chondrocyte proliferation, Chantal Forristal, Shauna A. Henley, James I. MacDonald, Jason R. Bush, Carley Ort, Daniel T. Passos, Srikanth Talluri, Charles A. Ishak, Michael J. Thwaites, Chris J. Norley, Larisa Litovchick, James A. DeCaprio, Gabriel DiMattia, David W. Holdsworth, Frank Beier, and Frederick A. Dick
Biased signalling and proteinase-activated receptors (PARs): Targeting inflammatory disease, M. D. Hollenberg, K. Mihara, D. Polley, J. Y. Suen, A. Han, D. P. Fairlie, and R. Ramachandran