Bone and Joint Institute
The Bone and Joint Institute positions Western as a global leader in research and innovation in musculoskeletal health. With over 145 members, the Institute brings together a critical mass of experts across disciplines to achieve high-impact transdisciplinary research for the benefit of millions of Canadians suffering from pain and reduced mobility.
Visit the Bone and Joint Institute website for additional information.
Browse The Bone and Joint Institute Publications
Submissions from 2015
Surgical approach in primary total hip arthroplasty: Anatomy, technique and clinical outcomes, Stephen Petis, James L. Howard, Brent L. Lanting, and Edward M. Vasarhelyi
Synthetic glycopolypeptides: Synthesis and self-assembly of poly(γ-benzyl-L-glutamate)-glycosylated dendron hybrids, Ariane Peyret, John F. Trant, Colin V. Bonduelle, Khalid Ferji, Namrata Jain, Sebastien Lecommandoux, and Elizabeth R. Gillies
Are Nucleated Cell Counts Useful in the Diagnosis of Infection in Periprosthetic Fracture?, Stephen Preston, Lyndsay Somerville, Brent Lanting, and James Howard
Synthesis and Characterization of a Family of Air-Stable Ferrocene- and Ruthenocene-Containing Primary, Secondary, and Tertiary Phosphines, Amir Rabiee Kenaree, Tyler J. Cuthbert, Stephanie M. Barbon, Paul D. Boyle, Elizabeth R. Gillies, Paul J. Ragogna, and Joe Gilroy
Outcomes and complications of ulnar shortening osteotomy: an institutional review, Raghav Rajgopal, James Roth, Graham King, Ken Faber, and Ruby Grewal
Peroxisome proliferator-activated receptor δ promotes the progression of posttraumatic osteoarthritis in a mouse model, A. Ratneswaran, E. A. LeBlanc, E. Walser, I. Welch, J. S. Mort, N. Borradaile, and F. Beier
A top-notch dilemma: The complex role of NOTCH signaling in osteoarthritis, Anusha Ratneswaran and Frank Beier
Radiographic landmarks for surgical reconstruction of the anterolateral ligament of the knee, Alex J. Rezansoff, Scott Caterine, Luke Spencer, Michael N. Tran, Robert B. Litchfield, and Alan M. Getgood
Meniscal integrity predicts laxity of anterior cruciate ligament reconstruction, Curtis Robb, Peter Kempshall, Alan Getgood, Hayley Standell, Andrew Sprowson, Peter Thompson, and Tim Spalding
The le fort system revisited: Trauma velocity predicts the path of le fort i fractures through the lateral buttress, Grayson Roumeliotis, Romy Ahluwalia, Thomas Jenkyn, and Arjang Yazdani
Application of a Novel Semi-Automatic Technique for Determining the Bilateral Symmetry Plane of the Facial Skeleton of Normal Adult Males, Grayson Roumeliotis, Ryan Willing, Mark Neuert, Romy Ahluwalia, Thomas Jenkyn, and Arjang Yazdani
Diagnostic accuracy of ultrasonography, MRI and MR arthrography in the characterisation of rotator cuff disorders: A systematic review and meta-analysis, Jean Sébastien Roy, Caroline BraÃn, Jean Leblond, François Desmeules, Clermont E. Dionne, Joy C. MacDermid, Nathalie J. Bureau, and Pierre Frémont
Intention toward implementation of stroke rehabilitation clinical practice guidelines: An application of the theory of planned behavior, Ahmad Sahely, Joy C. MacDermid, and Rahul Mota
Curcumin-loaded, folic acid-functionalized magnetite particles for targeted drug delivery, Melessa Salem, Ying Xia, Alison Allan, Sohrab Rohani, and Elizabeth R. Gillies
Unstable chest wall injuries: Future directions, Emil H. Schemitsch and Zachary Morison
Prognostic Factors for Reoperation After Plate Fixation of the Midshaft Clavicle, Laura A. Schemitsch, Emil H. Schemitsch, Paul Kuzyk, and Michael D. McKee
Improvement in outcomes after implantation of a novel polyurethane meniscal scaffold for the treatment of medial meniscus deficiency, Karl F. Schüttler, Steffen Pöttgen, Alan Getgood, Marga B. Rominger, Susanne Fuchs-Winkelmann, Philip P. Roessler, Ewgeni Ziring, and Turgay Efe
The effect of radial head implant shape on radiocapitellar kinematics during invitro forearm rotation, Hannah L. Shannon, Simon R. Deluce, Joshua W. Giles, James A. Johnson, and Graham J.W. King
Effect of radial head implant shape on joint contact area and location during static loading, Hannah L. Shannon, Simon R. Deluce, Emily A. Lalone, Ryan Willing, Graham J.W. King, and James A. Johnson
Building networks for global clinical research: The basics, David W. Shearer, Paul A. Volberding, Emil H. Schemitsch, Gillian E. Cook, Gerard P. Slobogean, and Saam Morshed
Forebrain neurocircuitry associated with human reflex cardiovascular control, J. Kevin Shoemaker and Ruma Goswami
Forebrain organization for autonomic cardiovascular control, J. Kevin Shoemaker, Katelyn N. Norton, J. Baker, and T. Luchyshyn
Fracture resistance of commonly used self-drilling orthodontic mini-implants, Angie Smith, Yara K. Hosein, Cynthia E. Dunning, and Ali Tassi
A comparison of covalent and noncovalent strategies for paclitaxel release using poly(ester amide) graft copolymer micelles, Abdolrasoul Soleimani, Mahmoud M.Abd Rabo Moustafa, Aneta Borecki, and Elizabeth R. Gillies
Biomechanical Analysis of Simulated Clinical Testing and Reconstruction of the Anterolateral Ligament of the Knee, Luke Spencer, Timothy A. Burkhart, Michael N. Tran, Alex James Rezansoff, Shaneel Deo, Scott Caterine, and Alan M. Getgood
Influence of phase correction of late gadolinium enhancement images on scar signal quantification in patients with ischemic and non-ischemic cardiomyopathy, John Stirrat, Sebastien Xavier Joncas, Michael Salerno, Maria Drangova, and James White
Associations between heart rate variability, metabolic syndrome risk factors, and insulin resistance, Melanie I. Stuckey, Antti Kiviniemi, Dawn P. Gill, J. Kevin Shoemaker, and Robert J. Petrella
The relationship between the patient-rated Ulnar nerve evaluation and the common impairment measures of grip strength, pinch strength, and sensation, Mike Szekeres, Joy C. Macdermid, Graham J.W. King, and Ruby Grewal
A new method for measuring forearm rotation using a modified finger goniometer, Mike Szekeres, Joy C. MacDermid, and Joanne Rooney
Contribution of Surface Polishing and Sterilization Method to Backside Wear in Total Knee Arthroplasty, Matthew G. Teeter, Brent A. Lanting, Kush R. Shrestha, James L. Howard, and Edward M. Vasarhelyi
Radiostereometric analysis of early anatomical changes following medial opening wedge high tibial osteotomy, Matthew G. Teeter, Kristyn M. Leitch, and Dietrich Pape
Covalent Polyisobutylene-Paclitaxel Conjugates for Controlled Release from Potential Vascular Stent Coatings, John F. Trant, Matthew J. McEachran, Inderpreet Sran, Bethany A. Turowec, John R. De Bruyn, and Elizabeth R. Gillies
Synthesis and properties of arborescent polyisobutylene derivatives and a paclitaxel conjugate: Towards stent coatings with prolonged drug release, John F. Trant, Inderpreet Sran, John R. De Bruyn, Mark Ingratta, Aneta Borecki, and Elizabeth R. Gillies
Menstrual cycle and sex effects on sympathetic responses to acute chemoreflex stress, Charlotte W. Usselman, Tamara I. Gimon, Chantelle A. Nielson, Torri A. Luchyshyn, Nicole S. Coverdale, Stan H.M. Van Uum, and J. Kevin Shoemaker
Measuring health-related quality of life (HRQOL) in HIV-positive individuals— Content analyses of measures based on the international classification of functioning, disability, and health (ICF) and generic and disability core set, Saipriya Vajravelu, Joy C. Macdermid, Rahul Mota, Fatma Hasani, Saravanan Esakki, and Patty Solomon
The Impact of Wear and Lift-Off on Coronal Plane Alignment in TKA and Implications to Future Constrained Revision: A Retrieval Study, Pieter Jan T.K. Vandekerckhove, Matthew G. Teeter, Douglas D.R. Naudie, James L. Howard, Steven J. MacDonald, and Brent A. Lanting
The structure and function of the anterolateral ligament of the knee: A systematic review, Leon Van Der Watt, Moin Khan, Benjamin B. Rothrauff, Olufemi R. Ayeni, Volker Musahl, Alan Getgood, and Devin Peterson
Linking of the Patient Rated Elbow Evaluation (PREE) and the American Shoulder and Elbow Surgeons - Elbow questionnaire (pASES-e) to the International Classification of Functioning Disability and Health (ICF) and hand core sets, Joshua I. Vincent, Joy C. Macdermid, Graham J.W. King, and Ruby Grewal
Rasch analysis of the Patient Rated Elbow Evaluation questionnaire, Joshua I. Vincent, Joy C. MacDermid, Graham J.W. King, and Ruby Grewal
Erratum: Regression Segmentation for M3 Spinal Images (IEEE Transactions on Medical Imaging (2008) 34:8 (1640-1648)), Zhijie Wang, Xiantong Zhen, Kengyeow Tay, Said Osman, Walter Romano, and Shuo Li
Regression Segmentation for M3 Spinal Images, Zhijie Wang, Xiantong Zhen, Kengyeow Tay, Said Osman, Walter Romano, and Shuo Li
Understanding why people do or do not engage in activities following total joint replacement: A longitudinal qualitative study, F. Webster, A. V. Perruccio, R. Jenkinson, S. Jaglal, E. Schemitsch, J. P. Waddell, V. Venkataramanan, J. Bytautas, and A. M. Davis
Methods and considerations for the analysis and standardization of assessing muscle sympathetic nerve activity in humans, Daniel W. White, J. Kevin Shoemaker, and Peter B. Raven
Functional aqueous assemblies of linear-dendron hybrids, Greg Whitton and Elizabeth R. Gillies
Contact mechanics of reverse engineered distal humeral hemiarthroplasty implants, Ryan Willing, Graham J.W. King, and James A. Johnson
Regional variations in cartilage thickness of the radial head: Implications for prosthesis design, Celine Yeung, Simon Deluce, Ryan Willing, Marjorie Johnson, Graham J.W. King, and George S. Athwal
Multilineage co-culture of adipose-derived stem cells for tissue engineering, Yimu Zhao, Stephen D. Waldman, and Lauren E. Flynn
Submissions from 2014
Negative regulation of the peptidylarginine deiminase type IV promoter by NF-κB in human myeloid cells, Ali K. Abbas, Kevin Le, Virginia L. Pimmett, David A. Bell, Ewa Cairns, and Rodney P. DeKoter
Reconstruction of the coronoid process using the tip of the ipsilateral olecranon, Bashar Alolabi, Alia Gray, Louis M. Ferreira, James A. Johnson, George S. Athwal, and Graham J.W. King
Serum cytokine profile of unaffected first-degree relatives of patients with rheumatoid arthritis, Lillian Barra, Kelly Summers, David Bell, and Ewa Cairns
Appropriate Osteoporosis Treatment by Family Physicians inResponse to FRAX vs CAROC Reporting: Results Froma Randomized Controlled Trial, Karen A. Beattie, George Ioannidis, Joy C. MacDermid, Ruby Grewal, Alexandra Papaioannou, Jonathan D. Adachi, and Anthony B. Hodsman
Application of 3-d echocardiography and gated micro-computed tomography to assess cardiomyopathy in a mouse model of duchenne muscular dystrophy., Andrew B Bondoc, Sarah Detombe, Joy Dunmore-Buyze, Kelly M Gutpell, Linshan Liu, Amanda Kaszuba, Seongryoung Han, Rebecca McGirr, Jennifer Hadway, Maria Drangova, and Lisa M Hoffman
The rotator cuff quality-of-life index predicts the outcome of nonoperative treatment of patients with a chronic rotator cuff tear, Richard S. Boorman, Kristie D. More, Robert M. Hollinshead, J. Preston Wiley, Kelly Brett, Nicholas G. Mohtadi, Atiba A. Nelson, Ian K.Y. Lo, and Dianne Bryant
MULTI-MODAL PHYSIOTHERAPY AND HIGH TIBIAL OSTEOTOMY CAN MITIGATE RISK FACTORS FOR DISEASE PROGRESSION IN PATIENTS WITH VARUS GONARTHROSIS, A. Boulougouris, T. B. Birmingham, and T. D. Olver
A randomized controlled trial of nonoperative treatment versus open reduction and internal fixation for stable, displaced, partial articular fractures of the radial head: The RAMBO trial, Wendy Bruinsma, Izaäk Kodde, Robert Jan De Muinck Keizer, Peter Kloen, Anneluuk Lindenhovius, Jos Vroemen, Robert Haverlag, Michel Van Den Bekerom, Hugo Bolhuis, Pieter Bullens, Sven Meylaerts, Peer Van Der Zwaal, Philip Steller, Michiel Hageman, David Ring, Dennis Den Hartog, Eric Hammacher, Graham King, George Athwal, Ken Faber, Darren Drosdowech, Ruby Grewal, J. Carel Goslings, Niels Schep, and Denise Eygendaal
The effects of ulnar styloid fractures on patients sustaining distal radius fractures, Parham Daneshvar, Robert Chan, Joy Macdermid, and Ruby Grewal
Remplissage versus Latarjet for engaging Hill-Sachs defects without substantial glenoid bone loss: A biomechanical comparison, Ryan M. Degen, Joshua W. Giles, James A. Johnson, and George S. Athwal
Hemiarthroplasty of the elbow: The effect of implant size on kinematics and stability, Sagar J. Desai, George S. Athwal, Louis M. Ferreira, Emily A. Lalone, James A. Johnson, and Graham J.W. King
An anthropometric study of the distal humerus, Sagar J. Desai, Simon Deluce, James A. Johnson, Louis M. Ferreira, Alexandre E. Leclerc, George S. Athwal, and Graham J.W. King
Factors affecting transfusion requirement after hip fracture: Can we reduce the need for blood?, Sagar J. Desai, Kristi S. Wood, Jackie Marsh, Dianne Bryant, Hussein Abdo, Abdel Rahman Lawendy, and David W. Sanders
Characterization of a far-red analog of ghrelin for imaging GHS-R in P19-derived cardiomyocytes., Gregory A F Douglas, Rebecca McGirr, Carlie L Charlton, Dov B Kagan, Lisa M Hoffman, Leonard G Luyt, and Savita Dhanvantari
Polyglyoxylates: A versatile class of triggerable self-immolative polymers from readily accessible monomers, Bo Fan, John F. Trant, Andrew D. Wong, and Elizabeth R. Gillies
The bristow and latarjet procedures: Why these techniques should not be considered synonymous, Joshua W. Giles, Ryan M. Degen, James A. Johnson, and George S. Athwal
Versatile strained alkyne modified water-soluble AuNPs for interfacial strain promoted azide-alkyne cycloaddition (I-SPAAC), Pierangelo Gobbo, Zack Mossman, Ali Nazemi, Aurelia Niaux, Mark C. Biesinger, Elizabeth R. Gillies, and Mark S. Workentin
The effect of stem material and surface treatment on the torsional stability at the metal-cement interface of upper limb joint replacement systems, Yara K. Hosein, Graham J.W. King, and Cynthia E. Dunning
A retrospective comparative study with historical control to determine the effectiveness of platelet-rich plasma as part of nonoperative treatment of acute Achilles tendon rupture, Nicole Kaniki, Kevin Willits, Nicholas G.H. Mohtadi, Vincent Fung, and Dianne Bryant
Bacterial Superantigens Promote Acute Nasopharyngeal Infection by Streptococcus pyogenes in a Human MHC Class II-Dependent Manner, Katherine J. Kasper, Joseph J. Zeppa, Adrienne T. Wakabayashi, Stacey X. Xu, Delfina M. Mazzuca, Ian Welch, Miren L. Baroja, Malak Kotb, Ewa Cairns, P. Patrick Cleary, S. M.Mansour Haeryfar, and John K. McCormick
Functional outcomes post-radial head arthroplasty: a systematic review of literature, Manraj Nirmal Kaur, Joy C. MacDermid, Ruby R. Grewal, Paul W. Stratford, and Linda J. Woodhouse
An analysis of functional shoulder movements during task performance using Dartfish movement analysis software, Leenesh Khadilkar, Joy C. MacDermid, and Kathryn E. Sinden
Biomimetic l-aspartic acid-derived functional poly(ester amide)s for vascular tissue engineering, Darryl K. Knight, Elizabeth R. Gillies, and Kibret Mequanint
Vascular grafting strategies in coronary intervention, Darryl K. Knight, Elizabeth R. Gillies, and Kibret Mequanint
ADAMTS-7 forms a positive feedback loop with TNF-α in the pathogenesis of osteoarthritis, Yongjie Lai, Xiaohui Bai, Yunpeng Zhao, Qingyun Tian, Ben Liu, Edward A. Lin, Yuqing Chen, Brendan Lee, C. Thomas Appleton, Frank Beier, Xiu Ping Yu, and Chuan Ju Liu
A cohort study of one-year functional and radiographic outcomes following intra-articular distal radius fractures, Emily A. Lalone, Vaishnav Rajgopal, James Roth, Ruby Grewal, and Joy C. MacDermid
The effect of radial head implant length on radiocapitellar articular properties and load transfer within the forearm, Brent A. Lanting, Louis M. Ferreira, James A. Johnson, Graham J.W. King, and George S. Athwal
The effect of distal humeral hemiarthroplasty on articular contact of the elbow, Michael Lapner, Ryan Willing, James A. Johnson, and Graham J.W. King
EFFECTS OF MEDIAL OPENING WEDGE HIGH TIBIAL OSTEOTOMY ON MOMENTS ABOUT THE KNEE DURING WALKING AND STAIR CLIMBING, K. M. Leitch, T. B. Birmingham, and C. E. Dunning
Complications associated with operative versus nonsurgical treatment of distal radius fractures in patients aged 65 years and older, Kristina Lutz, Kwan M. Yeoh, Joy C. Macdermid, Caitlin Symonette, and Ruby Grewal
GAIT BIOMECHANICS PRE AND POST COMBINED HIGH TIBIAL OSTEOTOMY AND ACL RECONSTRUCTION, K. A. Marriott, T. B. Birmingham, and R. J. Giffin
Seasonal accumulation of acetylated triacylglycerols by a freeze-tolerant insect, Katie E. Marshall, Raymond H. Thomas, Aron Roxin, Eric K.Y. Chen, Jason C.L. Brown, Elizabeth R. Gillies, and Brent J. Sinclair
Adverse Event Rates and Classifications in Medial Opening Wedge High Tibial Osteotomy, Robin Martin, Trevor B. Birmingham, and Kevin Willits
Synthesis, self-assembly, and degradation of amphiphilic triblock copolymers with fully photodegradable hydrophobic blocks, J. Trevor McIntosh, Ali Nazemi, Colin V. Bonduelle, Sebastien Lecommandoux, and Elizabeth R. Gillies
A preference-based single-item measure of quality of life following medial opening wedge high tibial osteotomy: Large improvements similar to arthroplasty, Iain R. McNamara, Trevor B. Birmingham, and Jacquelyn D. Marsh
A structured literature synthesis to identify measures for screening for the risk of adverse outcomes in individuals following distal radius fracture, Saurabh P. Mehta, Joy C. MacDermid, Julie Richardson, Norma J. MacIntyre, and Ruby Grewal
Automatic and accurate reconstruction of distal humerus contours through B-Spline fitting based on control polygon deformation, Kamal Mostafavi, O. Remus Tutunea-Fatan, Evgueni V. Bordatchev, and James A. Johnson
A SYSTEMATIC REVIEW AND META-ANALYSIS OF BIOMECHANICAL AND CLINICAL EFFECTS OF VALGUS KNEE BRACING, R. Moyer, T. Birmingham, and K. Marriott
EFFECTS OF COMBINED CUSTOM VALGUS KNEE BRACE AND CUSTOM LATERAL WEDGE FOOT ORTHOTIC USE DURING STAIR ASCENT, R. Moyer, T. Birmingham, and K. Marriott
Osteoarthritis Year in Review 2014: mechanics - basic and clinical studies in osteoarthritis, R. F. Moyer, A. Ratneswaran, and F. Beier
Dendrimer Bioconjugates: Synthesis and Applications, Ali Nazemi and Elizabeth R. Gillies
Distal radioulnar joint kinematics in simulated dorsally angulated distal radius fractures, Masao Nishiwaki, Mark Welsh, Braden Gammon, Louis M. Ferreira, James A. Johnson, and Graham J.W. King
Open reduction and internal fixation of radial head fractures: Do outcomes differ between simple and complex injuries?, Jeffrey M. Pike, Ruby Grewal, George S. Athwal, Kenneth J. Faber, and Graham J.W. King
The influence on sarcopenia of muscle quality and quantity derived from magnetic resonance imaging and neuromuscular properties, Geoffrey A. Power, Matti D. Allen, William J. Booth, R. Terry Thompson, Greg D. Marsh, and Charles L. Rice
Humeral head reconstruction for hill-sachs defects: A biomechanical comparison of 2 fixation techniques for bone grafting, Gabor J. Puskas, Joshua W. Giles, Ryan M. Degen, James A. Johnson, and George S. Athwal
Curcumin, a promising anti-cancer therapeutic: A review of its chemical properties, bioactivity and approaches to cancer cell delivery, Melessa Salem, Sohrab Rohani, and Elizabeth R. Gillies
Antihomocitrullinated fibrinogen antibodies are specific to rheumatoid arthritis and frequently bind citrullinated proteins/peptides, Mathias Scinocca, David A. Bell, Maud Racapé, Radha Joseph, Gary Shaw, John K. McCormick, Dafna D. Gladman, Janet Pope, Lillian Barra, and Ewa Cairns
Short-term sensory and cutaneous vascular responses to therapeutic ultrasound in the forearms of healthy volunteers, Shaguftha S. Shaik, Joy C. MacDermid, Trevor Birmingham, Ruby Grewal, and Baseer Farooq
A systematic review of prognostic factors for return to work following work-related traumatic hand injury, Qiyun Shi, Kathryn Sinden, Joy C. Macdermid, David Walton, and Ruby Grewal
Staged medial opening wedge high tibial osteotomy for bilateral varus gonarthrosis: biomechanical and clinical outcomes, Emily L. Sischek, Trevor B. Birmingham, and Kristyn M. Leitch
Non-covalently functionalized single-walled carbon nanotube for topical siRNA delivery into melanoma, King Sun Siu, Di Chen, Xiufen Zheng, Xusheng Zhang, Nathan Johnston, Yanling Liu, Ken Yuan, James Koropatnick, Elizabeth R. Gillies, and Wei Ping Min
Single-walled carbon nanotubes noncovalently functionalized with lipid modified polyethylenimine for sirna delivery in vitro and in vivo, King S. Siu, Xiufen Zheng, Yanling Liu, Yujuan Zhang, Xusheng Zhang, Di Chen, Ken Yuan, Elizabeth R. Gillies, James Koropatnick, and Wei Ping Min
Photodegradable poly(ester amide)s for indirect light-triggered release of paclitaxel, Abdolrasoul Soleimani, Aneta Borecki, and Elizabeth R. Gillies