Anatomy and Cell Biology Theses and Dissertations

 

This collection contains theses and dissertations from the Department of Anatomy and Cell Biology, collected from the Scholarship@Western Electronic Thesis and Dissertation Repository

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Theses/Dissertations from 2016

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Investigating Stromal Contributions to the Regulation of Cancer Progression, Krista M. Vincent

Theses/Dissertations from 2015

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Design, Implementation, and Evaluation of an Online Systemic Human Anatomy Course with Laboratory, Stefanie M. Attardi

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Co-Morbidity Of Alzheimer’s Disease And Stroke: Cognitive Deficits And Cellular Pathologies In Two Co-Morbid Animal Models, Jennifer L. Au

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High Throughput Screening For Drug Discovery In Head And Neck Squamous Cell Carcinoma, Morgan D. Black

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Hierarchical Organization in Auditory Cortex of the Cat Using High-Field Functional Magnetic Resonance Imaging, Amee J. Hall

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The Role of Cytoplasmic Polyadenylation Element Binding Protein-2 (CPEB-2) in Breast Cancer, Asma Hasan

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Underlying Mechanisms Regulating Gingival Healing and Fibrosis, Shawna Soheun Kim

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Clinical and Experimental Importance of Circulating Tumor Cells in Prostate Cancer, Lori Lowes

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Analyzing A-series gangliosides in neurons following exposure to glutamate, Dae Hee Park

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The lung microenvironment influences the metastatic behaviour of breast cancer cells in an innovative 3D ex vivo pulmonary metastasis model, Matt M. Piaseczny

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The Role of Bone-Derived Osteopontin in the Migration and Stem-Like Behavior of Breast Cancer Cells, Graciella Pio

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Exploring And Training Spatial Reasoning Via Eye Movements: Implications On Performance, Victoria A. Roach

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Investigating the role of hydrogen sulfide in the survival, growth and angiogenic potential of clear cell renal cell carcinoma cell lines and xenografts, Eric Sonke

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Evaluating the pathological and behavioural consequences of injecting amyloid beta oligomers in the rat, Ryan S. Wong

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Mechanisms of neuroprotection against ischemic insult by stress-inducible phosphoprotein-1, Jason Xu

Theses/Dissertations from 2014

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Effects of an Angiotensin II Type 1 Receptor Blocker on Cardiovascular Calcification, Zachary B. Armstrong

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Investigation of Sox9 ablation on neuroplasticity and recovery after ischemic stroke, Bethany Robin Lenore Bass

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The Role of miR-526b in COX-2 Mediated Human Breast Cancer Progression and Induction of Stem-Like Phenotype Via EP4 Receptor Signaling, Erin O. Landman

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Sox9 conditional knockdown reduces chondroitin sulphate proteoglycan expression, increases neuroplasticity, and improves motor function in a mouse model of spinal cord injury, William M. McKillop

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Influence of Polycaprolactone and Basic Fibroblast Growth Factor on Gingival Fibroblasts, Sarah Michelsons

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Investigating Microenvironmental Regulation of Human Chordoma Cell Behaviour, Priya Patel

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Distinct roles of BMP and LKB1/AMPK signalling impacting ovarian cancer spheroid biology, Teresa M. Peart

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Genomic predictors of drug response to the alpha-specific phosphoinositol 3-kinase (PI3Ka-alpha) inhibitor BYL719 in head and neck cancers, Giananthony T. Rizzo

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Understanding the role of cholinergic tone in the pedunculopontine tegmental nucleus, Kaie Rosborough

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Investigating the Primate Prefrontal Cortex Correlates of Cognitive Deficits In the Ketamine Model of Schizophrenia, Kevin J. Skoblenick

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Synaptic architecture of the acoustic startle response pathway, Mahabba Smoka

Theses/Dissertations from 2013

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Cx43 Reduces Melanoma Growth Within a Keratinocyte Microenvironment and During Tumorigenesis in vivo, Mark J. Ableser

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Circadian rhythms in reward and underlying neural circuits, Ricardo M. Baltazar

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Effects of Prenatal Testosterone on the Reproductive and Metabolic Neurons of the Sheep Hypothalamus, Maria Cernea

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Evaluation of matricellular proteins as potential therapeutics for the treatment of human chronic skin wounds, Christopher G. Elliott

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Flexibly adapting to emotional cues: Examining the functional and structural correlates of emotional reactivity and emotion control in healthy and depressed individuals, Steven G. Greening

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P2X7 Nucleotide Receptor Signaling in Osteoblasts, Matthew W. Grol

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Spinal Cord Control of Ejaculatory Reflexes in Male Rats, Natalie Kozyrev

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Dopamine Modulation of Emotional Learning in the Medial Prefrontal Cortex, Nicole M. Lauzon

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Investigation of Sox9 Ablation on Neural Stem Cell Behaviour after Spinal Cord Injury, Stephen McDonald

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Cognitive Function in BK Channel Knock-Out Mice, Magdalena N. Mirkowski

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Investigating the pathological response to beta amyloid toxicity in rats: the role of age and the antioxidant catalase-SKL, Hayley J. Nell

Theses/Dissertations from 2012

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Transactional Distances In An Online Histology Laboratory Course, Michele L. Barbeau

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TRPM2 in the Central Nervous System: Physiological Role and Critical Regulatory Pathways, Jillian C. Belrose

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The Role of Nodal in the Regulation of Bi-Potential Trophoblast Progenitor Cells, Alia Cloutier-Bosworth

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The Role of ALDHhiCD44+ Cells in Breast Cancer Metastasis and Therapy Resistance, Alysha K. Croker

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Sexual Reward and Depression, Andrea R. Di Sebastiano

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The Role of MicroRNAs in Cyclooxygenase-2 Mediated Breast Cancer Progression, Leanna R. Dunn

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An investigation into the combined effects of β-amyloid toxicity and cerebral ischemia on the pathological expression of gangliosides., Jeffrey D. Hepburn

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Calclium-calmodulin regulation of TRPM2 currents, Brian M. W. Lockhart

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Stress Induced Protein 1 (STI1) protects neurons against Beta-Amyloid (Abeta) neurotoxicity, Amro Hasan Mohammad

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Anatomy: The Relationship Between Internal and External Visualizations, Ngan T. Nguyen

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Neuroplasticity in the Mesolimbic System Induced by Sexual Experience and Subsequent Reward Abstinence, Kyle Pitchers

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The Embryonic Protein Nodal Supports Metastatic Phenotypes in Breast Cancer, Daniela F. Quail

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Characterization of the Circadian Properties of Runt-related Transcription Factor 2 (Runx2) and its Role in the Suprachiasmatic Nucleus, Meghan E. Reale

Theses/Dissertations from 2011

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Fetal Growth Restriction: Molecular Mechanisms and Long-Term Outcomes, Caroline D. Albion

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Mutant Cx43 in Skin Differentiation and Disease, Jared M. Churko

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Effects of methamphetamine on sexual behavior, Karla S. Frohmader

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The Life Cycle of Pannexins: Trafficking, Cell Surface Dynamics, Turnover and Degradation, Ruchi Gehi

Theses/Dissertations from 2010

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Regulation of Akt and Wnt signalling by the dopamine D2 receptor and metabotropic glutamate receptor 2/3, Laurie P. Sutton