Department of Medicine Publications
As the largest department within the Schulich School of Medicine and Dentistry, the Department of Medicine hosts a vast range of research in its divisions. Research areas include cardiology, clinical immunology and allergy, clinical pharmacology, dermatology, critical care and emergency medicine, endocrinology and metabolism, gastroenterology, hematology, molecular toxicology, nephrology, respirology, and rheumatology.
Visit the Department of medicine website for additional information.
Submissions from 2024
Precision of metabolite-selective MRS measurements of glutamate, GABA and glutathione: A review of human brain studies., Kesavi Kanagasabai, Lena Palaniyappan, and Jean Theberge
Submissions from 2023
Cognitive decline in thrombotic thrombocytopenic purpura survivors: The role of white matter health as assessed by MRI., F Hannan, J Hamilton, C J Patriquin, K Pavenski, M T Jurkiewicz, L Tristao, A M Owen, P K Kosalka, S C L Deoni, J Théberge, J Mandzia, S H S Huang, and J D Thiessen
Identifying canonical and replicable multi-scale intrinsic connectivity networks in 100k+ resting-state fMRI datasets., A Iraji, Z Fu, A Faghiri, M Duda, J Chen, S Rachakonda, T DeRamus, P Kochunov, B M Adhikari, A Belger, J M Ford, D H Mathalon, G D Pearlson, S G Potkin, A Preda, J A Turner, T G M van Erp, J R Bustillo, K Yang, K Ishizuka, A Faria, A Sawa, K Hutchison, E A Osuch, Jean Theberge, C Abbott, B A Mueller, D Zhi, C Zhuo, S Liu, Y Xu, M Salman, J Liu, Y Du, J Sui, T Adali, and V D Calhoun
How the body remembers: Examining the default mode and sensorimotor networks during moral injury autobiographical memory retrieval in PTSD., Breanne E Kearney, Braeden A Terpou, Maria Densmore, Saurabh B Shaw, Jean Theberge, Rakesh Jetly, Margaret C McKinnon, and Ruth A Lanius
Social Capital Associates With Better Cognitive Health, Oral Health and Epigenetic Age Deceleration: Findings From the Canadian Longitudinal Study on Aging., Aileen Liang and Noha Gomaa
A tale of two targets: examining the differential effects of posterior cingulate cortex- and amygdala-targeted fMRI-neurofeedback in a PTSD pilot study, Jonathan M. Lieberman, Daniela Rabellino, Maria Densmore, Paul Frewen, David Steyrl, Frank Scharnowski, Jean Theberge, Niki Hosseini-Kamkar, Richard W.J. Neufeld, Rakesh Jetly, Benicio N. Frey, Tomas Ros, Ruth A. Lanius, and Andrew A. Nicholson
Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis., Kate Merritt, Robert A McCutcheon, André Aleman, Sarah Ashley, Katherine Beck, Wolfgang Block, Oswald J N Bloemen, Faith Borgan, Christiana Boules, Juan R Bustillo, Aristides A Capizzano, Jennifer M Coughlin, Anthony David, Camilo de la Fuente-Sandoval, Arsime Demjaha, Kara Dempster, Kim Q Do, Fei Du, Peter Falkai, Beata Galińska-Skok, Jürgen Gallinat, Charles Gasparovic, Cedric E Ginestet, Naoki Goto, Ariel Graff-Guerrero, Beng-Choon Ho, Oliver Howes, Sameer Jauhar, Peter Jeon, Tadafumi Kato, Charles A Kaufmann, Lawrence S Kegeles, Matcheri S Keshavan, Sang-Young Kim, Bridget King, Hiroshi Kunugi, J Lauriello, Pablo León-Ortiz, Edith Liemburg, Meghan E Mcilwain, Gemma Modinos, Elias Mouchlianitis, Jun Nakamura, Igor Nenadic, Dost Öngür, Miho Ota, Lena Palaniyappan, Christos Pantelis, Tulsi Patel, Eric Plitman, Sotirios Posporelis, Scot E Purdon, Jürgen R Reichenbach, Perry F Renshaw, Francisco Reyes-Madrigal, Bruce R Russell, Akira Sawa, Martin Schaefer, Dikoma C Shungu, Stefan Smesny, Jeffrey A Stanley, James Stone, Agata Szulc, Reggie Taylor, Katharine N Thakkar, Jean Theberge, Philip G Tibbo, Thérèse van Amelsvoort, Jerzy Walecki, Peter C Williamson, Stephen J Wood, Lijing Xin, Hidenori Yamasue, Philip McGuire, and Alice Egerton
Homeostatic normalization of alpha brain rhythms within the default-mode network and reduced symptoms in post-traumatic stress disorder following a randomized controlled trial of electroencephalogram neurofeedback., Andrew A Nicholson, Maria Densmore, Paul A Frewen, Richard W J Neufeld, Jean Theberge, Rakesh Jetly, Ruth A Lanius, and Tomas Ros
Hockey Fans In Training Graduate Program (HFIT Grad): Process Evaluation of an Add-on Fitness Program for HFIT Participants, Robert Petrella, Marisa Kfrerer, Olivia Crozier, Brendan Riggin, Wendy Blunt, Dawn P. Gill, and Brooke Bliss
Recruitment and characteristics of men with overweight/obesity from a trial of a gender-sensitized healthy lifestyle program, Robert Petrella, Melissa Majoni, Marisa Kferer, Narlon Boa Sorte Silva, Precious Adekoya, Brendan Riggin, Wendy Blunt, Dawn P. Gill, Brooke Bliss, Matthew DiNunzio, Paul Aspinall, and Jennifer Irwin
Hockey FIT for Women (HFIT for Women): Evaluating reach and implementation of a gender-sensitized healthy lifestyle program, Robert Petrella, Melissa Majoni, Marisa Kfrerer, Brendan Riggin, Wendy Blunt, Dawn P. Gill, Brooke Bliss, Olivia Crozier, and Paul Aspinall
Stakeholder Acceptability of the Hockey Fans In Training Healthy Lifestyle Intervention, Robert Petrella, Melissa Majoni, Marisa Kfrerer, Narlon Boa Sorte Silva, Brendan Riggin, Wendy Blunt, Dawn P. Gill, Brooke Bliss, Guangyong Zou, Kate Shillington, Paul Aspinall, and Jennifer Irwin
Can the power of sport help men with overweight/obesity improve their health through a tailored healthy lifestyle program?, Robert Petrella, Melissa Majoni, Marisa Kfrerer, Narton Boa Sorte Silva, Brendan Riggin, Wendy Blunt, Dawn P. Gill, Brooke Bliss, Guangyong Zou, Paul Aspinall, and Jennifer Irwin
Increased top-down control of emotions during symptom provocation working memory tasks following a RCT of alpha-down neurofeedback in PTSD., Saurabh Bhaskar Shaw, Andrew A Nicholson, Tomas Ros, Sherain Harricharan, Braeden Terpou, Maria Densmore, Jean Theberge, Paul Frewen, and Ruth A Lanius
Large-scale functional hyperconnectivity patterns in trauma-related dissociation: an rs-fMRI study of PTSD and its dissociative subtype, Saurabh B. Shaw, Braeden A. Terpou, Maria Densmore, Jean Theberge, Pau Frewen, Margaret C. McKinnon, and Ruth A. Lanius
Neuroimaging-based classification of PTSD using data-driven computational approaches: A multisite big data study from the ENIGMA-PGC PTSD consortium., Xi Zhu, Yoojean Kim, Orren Ravid, Xiaofu He, Benjamin Suarez-Jimenez, Sigal Zilcha-Mano, Amit Lazarov, Seonjoo Lee, Chadi G Abdallah, Michael Angstadt, Christopher L Averill, C Lexi Baird, Lee A Baugh, Jennifer U Blackford, Jessica Bomyea, Steven E Bruce, Richard A Bryant, Zhihong Cao, Kyle Choi, Josh Cisler, Andrew S Cotton, Judith K Daniels, Nicholas D Davenport, Richard J Davidson, Michael D DeBellis, Emily L Dennis, Maria Densmore, Terri deRoon-Cassini, Seth G Disner, Wissam El Hage, Amit Etkin, Negar Fani, Kelene A Fercho, Jacklynn Fitzgerald, Gina L Forster, Jessie L Frijling, Elbert Geuze, Atilla Gonenc, Evan M Gordon, Staci Gruber, Daniel W Grupe, Jeffrey P Guenette, Courtney C Haswell, Ryan J Herringa, Julia Herzog, David Bernd Hofmann, Bobak Hosseini, Anna R Hudson, Ashley A Huggins, Jonathan C Ipser, Neda Jahanshad, Meilin Jia-Richards, Tanja Jovanovic, Milissa L Kaufman, Mitzy Kennis, Anthony King, Philipp Kinzel, Saskia B J Koch, Inga K Koerte, Sheri M Koopowitz, Mayuresh S Korgaonkar, John H Krystal, Ruth Lanius, Christine L Larson, Lauren A M Lebois, Gen Li, Israel Liberzon, Guang Ming Lu, Yifeng Luo, Vincent A Magnotta, Antje Manthey, Adi Maron-Katz, Geoffery May, Katie McLaughlin, Sven C Mueller, Laura Nawijn, Steven M Nelson, Richard W J Neufeld, Jack B Nitschke, Erin M O'Leary, Bunmi O Olatunji, Miranda Olff, Matthew Peverill, K Luan Phan, Rongfeng Qi, Yann Quidé, Ivan Rektor, Kerry Ressler, Pavel Riha, Marisa Ross, Isabelle M Rosso, Lauren E Salminen, Kelly Sambrook, Christian Schmahl, Martha E Shenton, Margaret Sheridan, Chiahao Shih, Maurizio Sicorello, Anika Sierk, Alan N Simmons, Raluca M Simons, Jeffrey S Simons, Scott R Sponheim, Murray B Stein, Dan J Stein, Jennifer S Stevens, Thomas Straube, Delin Sun, Jean Theberge, Paul M Thompson, Sophia I Thomopoulos, Nic J A van der Wee, Steven J A van der Werff, Theo G M van Erp, Sanne J H van Rooij, Mirjam van Zuiden, Tim Varkevisser, Dick J Veltman, Robert R J M Vermeiren, Henrik Walter, Li Wang, Xin Wang, Carissa Weis, Sherry Winternitz, Hong Xie, Ye Zhu, Melanie Wall, Yuval Neria, and Rajendra A Morey
Submissions from 2022
Association of Pediatric Buccal Epigenetic Age Acceleration With Adverse Neonatal Brain Growth and Neurodevelopmental Outcomes Among Children Born Very Preterm With a Neonatal Infection., Noha Gomaa, Chaini Konwar, Nicole Gladish, Stephanie H Au-Young, Ting Guo, Min Sheng, Sarah M Merrill, Edmond Kelly, Vann Chau, Helen M Branson, Linh G Ly, Emma G Duerden, Ruth E Grunau, Michael S Kobor, and Steven P Miller
2022 Canadian Cardiovascular Society Guideline for Use of GLP-1 Receptor Agonists and SGLT2 Inhibitors for Cardiorenal Risk Reduction in Adults, G.B. John Mancini, Eileen O'Meara, Shelley Zieroth, Mathieu Bernier, Alice Y.Y. Cheng, David Z.I. Cherney, Kim A. Connelly, Justin Ezekowitz, Ronald M. Goldenberg, Lawrence A. Leiter, Gihad Nesrallah, Breay W. Paty, Marie-Eve Piche, Peter Senior, Abhinav Sharma, Subodh Verma, Vincent Woo, Pol Darras, Jonathan Y. Gabor, Jean Gregoire, Eva Lonn, James A. Stone, Jean-Francois Yale, Colin Yeung, and Deborah Zimmerman
Homocysteine and Thrombophilia in Pulmonary Hypertension, J. David Spence
Risk from low blood pressure in frail older adults: diastolic pressure and pulse pressure are important, J. David Spence
Submissions from 2021
Sex differences in the intestinal microbiome: interactions with risk factors for atherosclerosis and cardiovascular disease, Shamon Ahmed and J. David Spence
Shouldn't Patients With Paradoxical Emboli and Thrombophilia Be Given Anticoagulant Agents?, M. Reza Azarpazhooh, Chrysi Bogiatzi, and J. David Spence
Stroke Prevention: Little-Known and Neglected Aspects, M. Reza Azarpazhooh, Chrysi Bogiatzi, and J. David Spence
Five-year outcomes of PFO closure or antiplatelet therapy for cryptogenic stroke, Scott E. Kasner, John F. Rhodes, Grethe Andersen, Helle K. Iversen, Jens E. Nielsen-Kudsk, Magnus Settergren, Christina Sjöstrand, Risto O. Roine, David Hildick-Smith, J. David Spence, and Lars Søndergaard
CONNed in Pregnancy, Spoorthy Kulkarni, Anna F. Dominiczak, Rhian M. Touyz, J. David Spence, Daniel Batlle, Mohammed Barigou, Morris Brown, Robert M. Carey, Fernando Elijovich, Sandra Taler, and Ian B. Wilkinson