Department of Medicine Publications

 

As the largest department within the Schulich School of Medicine and Dentistry, the Department of Medicine hosts a vast range of research in its divisions. Research areas include cardiology, clinical immunology and allergy, clinical pharmacology, dermatology, critical care and emergency medicine, endocrinology and metabolism, gastroenterology, hematology, molecular toxicology, nephrology, respirology, and rheumatology.

Visit the Department of medicine website for additional information.

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Submissions from 2017

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Neurometabolic abnormalities in schizophrenia and depression observed with magnetic resonance spectroscopy at 7 T, Reggie Taylor, Elizabeth A Osuch, Betsy Schaefer, Nagalingam Rajakumar, Richard W J Neufeld, Jean Theberge, and Peter C Williamson

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Desynchronization of autonomic response and central autonomic network connectivity in posttraumatic stress disorder, Janine Thome, Maria Densmore, Paul A Frewen, Margaret C McKinnon, Jean Théberge, Andrew A Nicholson, Julian Koenig, Julian F Thayer, and Ruth A Lanius

Submissions from 2016

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Latest Skirmishes in the Long-Term Battle between Carotid Endarterectomy and Stenting, Martin M. Brown and J. David Spence

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Pioglitazone after ischemic stroke or Transient Ischemic attack, W. N. Kernan, C. M. Viscoli, K. L. Furie, L. H. Young, S. E. Inzucchi, M. Gorman, P. D. Guarino, A. M. Lovejoy, P. N. Peduzzi, R. Conwit, L. M. Brass, G. G. Schwartz, H. P. Adams, L. Berger, A. Carolei, W. Clark, B. Coull, G. A. Ford, D. Kleindorfer, J. R. O'Leary, M. W. Parsons, P. Ringleb, S. Sen, J. D. Spence, D. Tanne, D. Wang, and T. R. Winder

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Adding carotid total plaque area to the Framingham risk score improves cardiovascular risk classification, Hernan A. Perez, Nestor Horacio Garcia, John David Spence, and Luis J. Armando

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Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest, P. Timothy Pollak and J. David Spence

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Folic acid therapy reduces the first stroke risk associated with hypercholesterolemia among hypertensive patients, Xianhui Qin, Jianping Li, J. David Spence, Yan Zhang, Youbao Li, Xiaobin Wang, Binyan Wang, Ningling Sun, Fang Chen, Jingxuan Guo, Delu Yin, Liming Sun, Genfu Tang, Mingli He, Jia Fu, Yefeng Cai, Xiuli Shi, Ping Ye, Hong Chen, Shuiping Zhao, Mao Chen, Chuanyu Gao, Xiangqing Kong, Fan Fan Hou, Yining Huang, and Yong Huo

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Aberrant Functional Connectivity of the Amygdala Complexes in PTSD during Conscious and Subconscious Processing of Trauma-Related Stimuli, Daniela Rabellino, Maria Densmore, Paul A Frewen, Jean Theberge, Margaret C McKinnon, and Ruth A Lanius

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Re: ‘Transcranial Doppler Ultrasound Detection of Microemboli as a Predictor of Cerebral Events in Patients with Symptomatic and Asymptomatic Carotid Disease: A Systematic Review and Meta-Analysis’, J. D. Spence

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Intestinal Microbiome and Atherosclerosis, J. David Spence

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Recent advances in pathogenesis, assessment, and treatment of atherosclerosis, J. David Spence

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Overcoming challenges with statin therapy, J. David Spence and George K. Dresser

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Appropriate management of asymptomatic carotid stenosis, J. David Spence, Hongsong Song, and Guanliang Cheng

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Effect of renal impairment on atherosclerosis: Only partially mediated by homocysteine, J. David Spence, Bradley L. Urquhart, and Heejung Bang

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Taking care of volunteers in a stroke trial: A new assisted-management strategy, Amber C. Stuart, Jason J. Sico, Catherine M. Viscoli, Ashis H. Tayal, Silvio E. Inzucchi, Gary A. Ford, Karen L. Furie, Robert Cote, J. David Spence, David Tanne, and Walter N. Kernan

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ACC Neuro-over-Connectivity Is Associated with Mathematically Modeled Additional Encoding Operations of Schizophrenia Stroop-Task Performance, Reggie Taylor, Jean Theberge, Peter C Williamson, Maria Densmore, and Richard W J Neufeld

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Folic acid supplementation and chronic kidney disease progression, Christina M. Wyatt and J. David Spence

Submissions from 2015

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iStent as a Solo Procedure for Glaucoma Patients: A Systematic Review and Meta-Analysis, Monali S. Malvankar-Mehta, Yufeng Nancy Chen, Yiannis Iordanous, Wan Wendy Wang, John Costella, and Cindy M. L. Hutnik

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Immediate versus Delayed Sequential Bilateral Cataract Surgery: A Systematic Review and Meta-Analysis, Monali S. Malvankar-Mehta, Yufeng Nancy Chen, Sangita Patel, Angela Pui-Kei Leung, Man Mohan Merchea, and William G. Hodge

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Management of resistant hypertension, J. David Spence

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Statins and cataracts: Reverse causality?, J. David Spence

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Risk of stroke at the time of carotid occlusion, Catherine Yang, Chrysi Bogiatzi, and J. David Spence

Submissions from 2014

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SPARKLE (Subtypes of ischaemic stroke classification system), Incorporating measurement of carotid plaque burden: A new validated tool for the classification of ischemic stroke subtypes, Chrysi Bogiatzi, Thapat Wannarong, A. Ian McLeod, Marnin Heisel, Daniel Hackam, and J. David Spence

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Effects of homocysteine lowering with B vitamins on cognitive aging: Meta-analysis of 11 trials with cognitive data on 22,000 individuals, Robert Clarke, Derrick Bennett, Sarah Parish, Sarah Lewington, Murray Skeaff, Simone J.P.M. Eussen, Catharina Lewerin, David J. Stott, Jane Armitage, Graeme J. Hankey, Eva Lonn, J. David Spence, Pilar Galan, Lisette C. De Groot, Jim Halsey, Alan D. Dangour, Rory Collins, and Francine Grodstein

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Practice Patterns and Trends in the Use of Medical Therapy in Patients Undergoing Percutaneous Coronary Intervention in Ontario, Pallav Garg, Harindra C. Wijeysundera, Lingsong Yun, Warren J. Cantor, and Dennis T. Ko