Homeostatic normalization of alpha brain rhythms within the default-mode network and reduced symptoms in post-traumatic stress disorder following a randomized controlled trial of electroencephalogram neurofeedback.

Authors

Andrew A Nicholson
Maria Densmore
Paul A Frewen
Richard W J Neufeld
Jean Theberge, The university of Western OntarioFollow
Rakesh Jetly
Ruth A Lanius
Tomas Ros

Document Type

Article

Publication Date

1-1-2023

Journal

Brain Communication

Volume

5

Issue

2

First Page

068

Last Page

068

URL with Digital Object Identifier

https://doi.org/10.1093/braincomms/fcad068

Abstract

Collective research has identified a key electroencephalogram signature in patients with post-traumatic stress disorder, consisting of abnormally reduced alpha (8-12 Hz) rhythms. We conducted a 20-session, double-blind, randomized controlled trial of alpha desynchronizing neurofeedback in patients with post-traumatic stress disorder over 20 weeks. Our objective was to provide mechanistic evidence underlying potential clinical improvements by examining changes in aberrant post-traumatic stress disorder brain rhythms (namely, alpha oscillations) as a function of neurofeedback treatment. We randomly assigned participants with a primary diagnosis of post-traumatic stress disorder (

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This work is licensed under a Creative Commons Attribution 4.0 License.