Research in Medical Biophysics Publications focuses on the application of physics in the human body and those of higher animals while examining topics such as blood flow, orthopedic mechanics, medical imaging and cancer biology. Research is conducted in partnership with clinicians at state-of-the-art facilities located at Western University, London Regional Cancer Program, Lawson Health Research Institute, Robarts Research Institute, and the London Health Sciences Centre.

Visit the Department of Medical Biophysics website for additional information.

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Submissions from 2009

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Nicotinamide Phosphoribosyltransferase Imparts Human Endothelial Cells with Extended Replicative Lifespan and Enhanced Angiogenic Capacity in a High Glucose Environment, Nica M. Borradaile and J. Geoffrey Pickering

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A Fully Automated Non-external Marker 4D-CT Sorting Algorithm Using a Serial Cine Scanning Protocol, Greg Carnes, Stewart Gaede, Edward Yu, Jake Van Dyk, Jerry Battista, and Ting-Yim Lee

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Analysis of carotid lumen surface morphology using three-dimensional ultrasound imaging, Bernard Chiu, Vadim Beletsky, J David Spence, Grace Parraga, and Aaron Fenster

New and current clinical imaging techniques to study chronic obstructive pulmonary disease, Harvey O Coxson, John Mayo, Stephen Lam, Giles Santyr, Grace Parraga, and Don D Sin

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Cardiac MR Elastography: Comparison with Left Ventricular Pressure Measurement, Thomas Elgeti, Michael Laule, Nikola Kaufels, Jorg Schnorr, Bernd Hamm, Abbas Samani, Jurgen Braun, and Ingolf Sack

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The Management of Thymoma: A Systematic Review and Practice Guideline, Conrad B. Falkson, Andrea Bezjak, Gail Darling, Richard Gregg, Richard Malthaner, Donna E. Maziak, Edward Yu, Christopher A. Smith, Sheila McNair, Yee C. Ung, William K. Evans, and Lung Cancer Disease Site Group of Cancer Care Ontario's Program in Evidence-Based Care

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Lipid Incorporation Inhibits Src-Dependent Assembly of Fibronectin and Type I Collagen by Vascular Smooth Muscle Cells, Matthew J. Frontini, Caroline O'Neil, Cynthia Sawyez, Bosco M. C. Chan, Murray W. Huff, and J. Geoffrey Pickering

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The Use of CT Density Changes at Internal Tissue Interfaces to Correlate Internal Organ Motion with an External Surrogate, Stewart Gaede, Gregory Carnes, Edward Yu, Jake Van Dyk, Jerry Battista, and Ting-Yim Lee

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SIRT1 Markedly Extends Replicative Lifespan if the NAD+ Salvage Pathway Is Enhanced, Cynthia Ho, Eric van der Veer, Oula Akawi, and J. Geoffrey Pickering

Magnetic resonance imaging and three-dimensional ultrasound of carotid atherosclerosis: Mapping regional differences, Adam Krasinski, Bernard Chiu, Aaron Fenster, and Grace Parraga

Three-dimensional ultrasound quantification of intensive statin treatment of carotid atherosclerosis, Adam Krasinski, Bernard Chiu, J David Spence, Aaron Fenster, and Grace Parraga

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Is Hemorrhage in Acute Reperfused Myocardial Infarction a New Marker for the Severity of Tissue Injury?, Andreas Kumar, Jordin D. Green, Jane M. Sykes, Andrea Mitchell, Gerald Wisenberg, and Matthias G. Friedrich

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Optimized MRI Contrast for On-resonance Proton Exchange Processes of PARACEST Agents in Biological Systems, Alex X. Li, Mojmir Suchy, Craig K. Jones, Robert H. E. Hudson, Ravi S. Menon, and Robert Bartha

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Management and Prognosis in Synchronous Solitary Resected Brain Metastasis from Non–Small-Cell Lung Cancer, Alexander V. Louie, George Rodrigues, Brian Yaremko, Edward Yu, A. Rashid Dar, Brian Dingle, Mark Vincent, Michael Sanatani, Richard Malthaner, and Richard Inculet

Prospective cardiac gating of carotid three-dimensional ultrasound, Christiane Mallett, Lori Gardi, Aaron Fenster, and Grace Parraga

Longitudinal ultrasound evaluation of carotid atherosclerosis in one, two and three dimensions, Christiane Mallett, Andrew A House, J David Spence, Aaron Fenster, and Grace Parraga

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An Alternative Kinase Activity Assay for Primary Cultures Derived from Clinical Isolates, Kristopher McLean, Yan Wu, Bing Siang Gan, and David B. O'Gorman

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Nonrigid registration of three-dimensional ultrasound and magnetic resonance images of the carotid arteries, Nuwan D Nanayakkara, Bernard Chiu, Abbas Samani, J David Spence, Jagath Samarabandu, Grace Parraga, and Aaron Fenster

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Lymphatic Metastasis of Breast Cancer Cells Is Associated with Differential Gene Expression Profiles that Predict Cancer Stem Cell-like Properties and the Ability to Survive, Establish and Grow in a Foreign Environment, Terlika S. Pandit, Wendy Kennette, Lisa Mackenzie, Guihua Zhang, Waleed Al-Katib, Joseph Andrews, Sharon A. Vantyghem, D. George Ormond, Alison L. Allan, David I. Rodenhiser, Ann F. Chambers, and Alan B. Tuck

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Enzyme-Sensitive Magnetic Resonance Imaging Targeting Myeloperoxidase Identifies Active Inflammation in Experimental Rabbit Atherosclerotic Plaques, John A. Ronald, John W. Chen, Yuanxin Chen, Amanda M. Hamilton, Elisenda Rodriguez, Fred Reynolds, Robert A. Hegele, Kem A. Rogers, Manel Querol, Alexei Bogdanov, Ralph Weissleder, and Brian K. Rutt

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Comparison of Gadofluorine-M and Gd-DTPA for Noninvasive Staging of Atherosclerotic Plaque Stability Using MRI, John A. Ronald, Yuanxin Chen, Andre J.-L. Belisle, Amanda M. Hamilton, Kem A. Rogers, Robert A. Hegele, Bernd Misselwitz, and Brian K. Rutt

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Clinical Field-strength MRI of Amyloid Plaques Induced by Low-level Cholesterol Feeding in Rabbits, John A. Ronald, Yuanxin Chen, Lisa Bernas, Hagen H. Kitzler, Kem A. Rogers, Robert A. Hegele, and Brian K. Rutt

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Nuclear Degradation of Wilms Tumor 1-associating Protein and Survivin Splice Variant Switching Underlie IGF-1-mediated Survival, Theodore W. Small and J. Geoffrey Pickering

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Cardiac Tumours, Patricia Tai and Edward Yu

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A Long-Term Study of Radiation Therapy in T1-2 Node-Negative Breast Cancer Patients in Relation to the Number of Axillary Nodes Examined, Patricia Tai, Edward Yu, Evgeny Sadikov, and Kurian Joseph