Research in Medical Biophysics Publications focuses on the application of physics in the human body and those of higher animals while examining topics such as blood flow, orthopedic mechanics, medical imaging and cancer biology. Research is conducted in partnership with clinicians at state-of-the-art facilities located at Western University, London Regional Cancer Program, Lawson Health Research Institute, Robarts Research Institute, and the London Health Sciences Centre.

Visit the Department of Medical Biophysics website for additional information.

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Submissions from 2012

Regional pulmonary response to a methacholine challenge using hyperpolarized (3)He magnetic resonance imaging, Stephen Costella, Miranda Kirby, Geoffrey N Maksym, David G McCormack, Nigel A M Paterson, and Grace Parraga

Hyperpolarized 3He magnetic resonance functional imaging semiautomated segmentation, Miranda Kirby, Mohammadreza Heydarian, Sarah Svenningsen, Andrew Wheatley, David G McCormack, Roya Etemad-Rezai, and Grace Parraga

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Evaluating bronchodilator effects in chronic obstructive pulmonary disease using diffusion-weighted hyperpolarized helium-3 magnetic resonance imaging, Miranda Kirby, Mohammadreza Heydarian, Andrew Wheatley, David G McCormack, and Grace Parraga

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Evidence of adult lung growth in humans., Miranda Kirby, David G McCormack, and Grace Parraga

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Hyperpolarized 3He and 129Xe MR imaging in healthy volunteers and patients with chronic obstructive pulmonary disease, Miranda Kirby, Sarah Svenningsen, Amir Owrangi, Andrew Wheatley, Adam Farag, Alexei Ouriadov, Giles E Santyr, Roya Etemad-Rezai, Harvey O Coxson, David G McCormack, and Grace Parraga

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Modeling stochastic and spatial heterogeneity in a human airway tree to determine variation in respiratory system resistance, Del Leary, Swati A Bhatawadekar, Grace Parraga, and Geoffrey N Maksym

Four-dimensional x-ray computed tomography and hyperpolarized 3He magnetic resonance imaging of gas distribution in lung cancer, L Mathew, R Castillo, E Castillo, B Yaremko, G Rodrigues, R Etemad-Rezai, T Guerrero, and G Parraga

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Hyperpolarized 3He functional magnetic resonance imaging of bronchoscopic airway bypass in chronic obstructive pulmonary disease., Lindsay Mathew, Miranda Kirby, Donald Farquhar, Christopher Licskai, Giles Santyr, Roya Etemad-Rezai, Grace Parraga, and David G McCormack

Hyperpolarized (3)He pulmonary functional magnetic resonance imaging prior to radiation therapy, Lindsay Mathew, Jake Vandyk, Roya Etemad-Rezai, George Rodrigues, and Grace Parraga

Hyperpolarized (3)He magnetic resonance imaging: Comparison with four-dimensional x-ray computed tomography imaging in lung cancer, Lindsay Mathew, Andrew Wheatley, Richard Castillo, Edward Castillo, George Rodrigues, Thomas Guerrero, and Grace Parraga

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Chest MRI in children: Why bother?, Amir M Owrangi and Grace Parraga

Hyperpolarized 129Xe magnetic resonance imaging: Tolerability in healthy volunteers and subjects with pulmonary disease, Yajur Shukla, Andrew Wheatley, Miranda Kirby, Sarah Svenningsen, Adam Farag, Giles E Santyr, Nigel A M Paterson, David G McCormack, and Grace Parraga

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What can computed tomography and magnetic resonance imaging tell us about ventilation?, Brett A Simon, David W Kaczka, Alexander A Bankier, and Grace Parraga

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Shift work and vascular events: Systematic review and meta-analysis., Manav V Vyas, Amit X Garg, Arthur V Iansavichus, John Costella, Allan Donner, Lars E Laugsand, Imre Janszky, Marko Mrkobrada, Grace Parraga, and Daniel G Hackam

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Quantitative pulmonary imaging using computed tomography and magnetic resonance imaging, George R Washko, Grace Parraga, and Harvey O Coxson

Submissions from 2011

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Use of Imaging Biomarkers to Assess Perfusion and Glucose Metabolism in the Skeletal Muscle of Dystrophic Mice, Nabeel Ahmad, Ian Welch, Robert Grange, Jennifer Hadway, Savita Dhanvantari, David Hill, Ting-Yim Lee, and Lisa M Hoffman

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An Automated Cell-counting Algorithm for Fluorescently-stained Cells in Migration Assays, Baraa K. Al-Khazraji, Philip J. Medeiros, Nicole M. Novielli, and Dwayne N. Jackson

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Three-dimensional ultrasound scanning, Aaron Fenster, Grace Parraga, and Jeff Bax

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Elimination of the Vesicular Acetylcholine Transporter in the Striatum Reveals Regulation of Behaviour by Cholinergic-Glutamatergic Co-Transmission, Monica S. Guzman, Xavier De Jaeger, Sanda Raulic, Ivana A. Souza, Alex X. Li, Susanne Schmid, Ravi S. Menon, Raul R. Gainetdinov, Marc G. Caron, Robert Bartha, Vania F. Prado, and Marco A. M. Prado

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Technology Assessment of Automated Atlas Based Segmentation in Prostate Bed Contouring, Jeremiah Hwee, Alexander V. Louie, Stewart Gaede, Glenn Bauman, David D'Souza, Tracy Sexton, Michael Lock, Belal Ahmad, and George Rodrigues

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Chronic obstructive pulmonary disease: Quantification of bronchodilator effects by using hyperpolarized ³He MR imaging, Miranda Kirby, Lindsay Mathew, Mohammadreza Heydarian, Roya Etemad-Rezai, David G McCormack, and Grace Parraga

Quantitative evaluation of hyperpolarized helium-3 magnetic resonance imaging of lung function variability in cystic fibrosis, Miranda Kirby, Sarah Svenningsen, Hassaan Ahmed, Andrew Wheatley, Roya Etemad-Rezai, Nigel A M Paterson, and Grace Parraga

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Proton Magnetic Resonance Spectroscopy of the Motor Cortex in Cervical Myelopathy, Izabela Kowalczyk, Neil Duggal, and Robert Bartha

Hyperpolarized ³He magnetic resonance imaging: Preliminary evaluation of phenotyping potential in chronic obstructive pulmonary disease, Lindsay Mathew, Miranda Kirby, Roya Etemad-Rezai, Andrew Wheatley, David G McCormack, and Grace Parraga

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Gene Signatures of Breast Cancer Progression and Metastasis, David I. Rodenhiser, Joseph D. Andrews, Theodore A. Vandenberg, and Ann F. Chambers