Biochemistry Publications

 

Scientists in the Department of Biochemistry have expertise in genome dynamics, epigenetics, and gene expression; human genetics and clinical biochemistry; signal transduction and intracellular communication; macromolecular structure and dynamics; proteomics; and bioinformatics.

Visit the Department of Biochemistry Research website for additional information,

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Submissions from 2009

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Phosphorylation-Induced Activation of the Response Regulator VraR from Staphylococcus aureus: Insights from Hydrogen Exchange Mass Spectrometry, Yu-Hong Liu, Antoaneta Belcheva, Lars Konermann, and Dasantila Golemi-Kotra

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De Novo Interpretation of Tandem Mass Spectra, Bin Ma and Gilles Lajoie

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Formation of Monomeric S100B and S100A11 Proteins at Low Ionic Strength, Nicole M. Marlatt, Brian L. Boys, Lars Konermann, and Gary S. Shaw

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An Alternative Kinase Activity Assay for Primary Cultures Derived from Clinical Isolates, Kristopher McLean, Yan Wu, Bing Siang Gan, and David B. O'Gorman

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Altered Visual Function and Interneuron Survival in Atrx Knockout Mice: inference for the Human Syndrome, Chantal F. Medina, Chantal Mazerolle, Yaping Wang, Nathalie G. Bérubé, Stuart Coupland, Richard J. Gibbons, Valerie A. Wallace, and David J. Picketts

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Clinical and Molecular Heterogeneity in Patients with the CblD Inborn Error of Cobalamin Metabolism, Isabelle R. Miousse, David Watkins, David Coelho, Tony Rupar, Eric A. Crombez, Eric Vilain, Jonathan A. Bernstein, Tina Cowan, Christopher Lee-Messer, Gregory M. Enns, Brian Fowler, and David S. Rosenblatt

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Naringenin Prevents Dyslipidemia, Apolipoprotein B Overproduction, and Hyperinsulinemia in LDL Receptor-null Mice with Diet-induced Insulin Resistance, Erin E. Mulvihill, Emma M. Allister, Brian G. Sutherland, Dawn E. Telford, Cynthia G. Sawyez, Jane Y. Edwards, Janet M. Markle, Robert A. Hegele, and Murray W. Huff

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In-capillary Enrichment, Proteolysis and Separation Using Capillary Electrophoresis with Discontinuous Buffers: Application on Proteins with Moderately Acidic and Basic Isoelectric Points, Chandra A. Nesbitt and Ken K.-C. Yeung

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Functional and Complementary Phosphorylation State Attributes of Human Insulin-like Growth Factor-Binding Protein-1 (IGFBP-1) Isoforms Resolved by Free Flow Electrophoresis, Mikkel Nissum, Majida Abu Shehab, Ute Sukop, Javad M. Khosravi, Robert Wildgruber, Christoph Eckerskorn, Victor K. M. Han, and Madhulika B. Gupta

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SAP Binds to CD22 and Regulates B Cell Inhibitory Signaling and Calcium Flux, Elena A. Ostrakhovitch, Yefu Wang, and Shawn S.-C. Li

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Phosphorylation of Osteopontin Peptides Mediates Adsorption to and Incorporation into Calcium Oxalate Crystals, Jason O'Young, Sara Chirico, Nehal Al Tarhuni, Bernd Grohe, Mikko Karttunen, Harvey A. Goldberg, and Graeme K. Hunter

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Lymphatic Metastasis of Breast Cancer Cells Is Associated with Differential Gene Expression Profiles that Predict Cancer Stem Cell-like Properties and the Ability to Survive, Establish and Grow in a Foreign Environment, Terlika S. Pandit, Wendy Kennette, Lisa Mackenzie, Guihua Zhang, Waleed Al-Katib, Joseph Andrews, Sharon A. Vantyghem, D. George Ormond, Alison L. Allan, David I. Rodenhiser, Ann F. Chambers, and Alan B. Tuck

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Hydrogen/Deuterium Exchange Mass Spectrometry with Top-Down Electron Capture Dissociation for Characterizing Structural Transitions of a 17 kDa Protein, Jingxi Pan, Jun Han, Christoph H. Borchers, and Lars Konermann

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Solution-Phase Chelators for Suppressing Nonspecific Protein−Metal Interactions in Electrospray Mass Spectrometry, Jingxi Pan, Kun Xu, Xiaoda Yang, Wing-Yiu Choy, and Lars Konermann

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Mapping the Structure of an Integral Membrane Protein under Semi-Denaturing Conditions by Laser-Induced Oxidative Labeling and Mass Spectrometry, Yan Pan, Leonid Brown, and Lars Konermann

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Structural Characterization of an Integral Membrane Protein in Its Natural Lipid Environment by Oxidative Methionine Labeling and Mass Spectrometry, Yan Pan, Bradley B. Stocks, Leonid Brown, and Lars Konermann

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The Structural Basis of Gas-Responsive Transcription by the Human Nuclear Hormone Receptor REV-ERBβ, Keith I. Pardee, Xiaohui Xu, Jeff Reinking, Anja Schuetz, Aiping Dong, Suya Liu, Rongguang Zhang, Jens Tiefenbach, Gilles Lajoie, Alexander N. Plotnikov, Alexey Botchkarev, Henry M. Krause, and Aled Edwards

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Transcriptional Control by Adenovirus E1A Conserved Region 3 via p300/CBP, Peter Pelka, Jailal N. G. Ablack, Joseph Torchia, Andrew S. Turnell, Roger J. A. Grand, and Joe S. Mymryk

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Novel LPL Mutations Associated with Lipoprotein Lipase Deficiency: Two Case Reports and a Literature Review, Amit R. Rahalkar, Fiona Giffen, Bryan Har, Josephine Ho, Katherine M. Morrison, John Hill, Jian Wang, Robert A. Hegele, and Tisha Joy

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Carnitine Palmitoyltransferase IA Polymorphism P479L Is Common in Greenland Inuit and Is Associated with Elevated Plasma Apolipoprotein A-I, Chandheeb Rajakumar, Matthew R. Ban, Henian Cao, T Kue Young, Peter Bjerregaard, and Robert A. Hegele

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Transcobalamin II Deficiency at Birth, Rene Ratschmann, Milen Minkov, Ana Kis, Christina Hung, Tony Rupar, Adolf Mühl, Brian Fowler, Ebba Nexo, and Olaf A. Bodamer

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Design of High-affinity S100-target Hybrid Proteins, Atoosa Rezvanpour, Jeremy M. Phillips, and Gary S. Shaw

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Epigenetic Contributions to Cancer Metastasis, David I. Rodenhiser

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Ab Initio Exon Definition Using an Information Theory-based Approach, Peter K. Rogan

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Enzyme-Sensitive Magnetic Resonance Imaging Targeting Myeloperoxidase Identifies Active Inflammation in Experimental Rabbit Atherosclerotic Plaques, John A. Ronald, John W. Chen, Yuanxin Chen, Amanda M. Hamilton, Elisenda Rodriguez, Fred Reynolds, Robert A. Hegele, Kem A. Rogers, Manel Querol, Alexei Bogdanov, Ralph Weissleder, and Brian K. Rutt