Biochemistry Publications
Scientists in the Department of Biochemistry have expertise in genome dynamics, epigenetics, and gene expression; human genetics and clinical biochemistry; signal transduction and intracellular communication; macromolecular structure and dynamics; proteomics; and bioinformatics.
Visit the Department of Biochemistry Research website for additional information,
Submissions from 2009
Lipid Incorporation Inhibits Src-Dependent Assembly of Fibronectin and Type I Collagen by Vascular Smooth Muscle Cells, Matthew J. Frontini, Caroline O'Neil, Cynthia Sawyez, Bosco M. C. Chan, Murray W. Huff, and J. Geoffrey Pickering
γ-Radiation Induced Interstrand Cross-Links in PNA:DNA Heteroduplexes, Tsvetan G. Gantchev, Sonia Girouard, David W. Dodd, Filip Wojciechowski, Robert H. E. Hudson, and Darel J. Hunting
FXYD1, a Modulator of Na+,K+-ATPase Activity, Facilitates Female Sexual Development by Maintaining Gonadotrophin-Releasing Hormone Neuronal Excitability, C. Garcia-Rudaz, V. Deng, V. Matagne, O. K. Ronnekleiv, M. Bosch, V. Han, A. K. Percy, and S. R. Ojeda
2009 Canadian Cardiovascular Society/Canadian Guidelines for the Diagnosis and Treatment of Dyslipidemia and Prevention of Cardiovascular Disease in the Adult - 2009 Recommendations, Jacques Genest, Ruth McPherson, Jiri Frohlich, Todd Anderson, Norm Campbell, André Carpentier, Patrick Couture, Robert Dufour, George Fodor, Gordon A. Francis, Steven Grover, Milan Gupta, Robert A. Hegele, David C. Lau, Lawrence Leiter, Gary F. Lewis, Eva Lonn, G. B. John Mancini, Dominic Ng, Glen J. Pearson, Allan Sniderman, James A. Stone, and Ehud Ur
An RNA Hairpin Sequesters the Ribosome Binding Site of the Homing Endonuclease mobE Gene, Ewan A. Gibb and David R. Edgell
Smoking and the Risk of Breast Cancer in BRCA1 and BRCA2 Carriers: An Update, Ophira Ginsburg; Parviz Ghadirian; Jan Lubinski; Cezary Cybulski; Henry Lynch; Susan Neuhausen; Charmaine Kim-Sing; Mark Robson; Susan Domchek; Claudine Isaacs; Jan Klijn; Susan Armel; William D. Foulkes; Nadine Tung; Pal Moller; Ping Sun; Steven A. Narod; and Hereditary Breast Cancer Clinical Study Group, Toronto, ON
Activation of the Mitogen-Activated Protein Kinase Pathway by Bone Sialoprotein Regulates Osteoblast Differentiation, Jonathan A. R. Gordon, Graeme K. Hunter, and Harvey A. Goldberg
Bone Sialoprotein Stimulates Focal Adhesion-related Signaling Pathways: Role in Migration and Survival of Breast and Prostate Cancer Cells, Jonathan A. R. Gordon, Jaro Sodek, Graeme K. Hunter, and Harvey A. Goldberg
Stimulation of the Maltose Transporter ATPase by Unliganded Maltose Binding Protein, Alister D. Gould, Patrick G. Telmer, and Brian H. Shilton
Crystallization of Calcium Oxalates Is Controlled by Molecular Hydrophilicity and Specific Polyanion-Crystal Interactions, Bernd Grohe, Adam Taller, Peter L. Vincent, Long D. Tieu, Kem A. Rogers, Alexander Heiss, Esben S. Sørensen, Silvia Mittler, Harvey A. Goldberg, and Graeme K. Hunter
Cytokine Array Comparisons of Plasma from Cycling Fertile Women on Cycle Day 5 and Ovulation, Kota Hatta, Michael J. Bilinski, J. Kimberly Haladyn, Jessica J. Roy, Julie Horrocks, Marianne J. van den Heuvel, Victor K. Han, and B. Anne Croy
Plasma Lipoproteins: Genetic Influences and Clinical Implications, Robert A. Hegele
A Polygenic Basis for Four Classical Fredrickson Hyperlipoproteinemia Phenotypes that Are Characterized by Hypertriglyceridemia, Robert A. Hegele, Matthew R. Ban, Neil Hsueh, Brooke A. Kennedy, Henian Cao, Guang Yong Zou, Sonia Anand, Salim Yusuf, Murray W. Huff, and Jian Wang
Hypertriglyceridemia: Phenomics and Genomics, Robert A. Hegele and Rebecca L. Pollex
Hoofbeats, Zebras, and Insights into Insulin Resistance, Robert A. Hegele and Karen Reue
Meta-Analysis of the INSIG2 Association with Obesity Including 74,345 Individuals: Does Heterogeneity of Estimates Relate to Study Design?, Iris M. Heid, Cornelia Huth, Ruth J. F. Loos, Florian Kronenberg, Vera Adamkova, Sonia S. Anand, Kristin Ardlie, Heike Biebermann, Peter Bjerregaard, Heiner Boeing, Claude Bouchard, Marina Ciullo, Jackie A. Cooper, Dolores Corella, Christian Dina, James C. Engert, Eva Fisher, Francesc Francès, Philippe Froguel, Johannes Hebebrand, Robert A. Hegele, Anke Hinney, Margret R. Hoehe, Frank B. Hu, Jaroslav A. Hubacek, Steve E. Humphries, Steven C. Hunt, Thomas Illig, Marjo-Riita Järvelin, Marika Kaakinen, Barbara Kollerits, Heiko Krude, Jitender Kumar, Leslie A. Lange, Birgit Langer, Shengxu Li, Andreas Luchner, Helen N. Lyon, David Meyre, Karen L. Mohlke, Vincent Mooser, Almut Nebel, Thuy Trang Nguyen, Bernhard Paulweber, Louis Perusse, Lu Qi, Tuomo Rankinen, Dieter Rosskopf, Stefan Schreiber, Shantanu Sengupta, Rossella Sorice, Anita Suk, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Henry Völzke, Karani S. Vimaleswaran, Nicholas J. Wareham, Dawn Waterworth, Salim Yusuf, Cecilia Lindgren, Mark I. McCarthy, Christoph Lange, Joel N. Hirschhorn, Nan Laird, and H-Erich Wichmann
Mutations in SPINT2 Cause a Syndromic Form of Congenital Sodium Diarrhea, Peter Heinz-Erian, Thomas Müller, Birgit Krabichler, Melanie Schranz, Christian Becker, Franz Rüschendorf, Peter Nürnberg, Bernard Rossier, Mihailo Vujic, Ian W. Booth, Christer Holmberg, Cisca Wijmenga, Giedre Grigelioniene, C. M. Frank Kneepkens, Stefan Rosipal, Martin Mistrik, Matthias Kappler, Laurent Michaud, Ludwig-Christoph Dóczy, Victoria Mok Siu, Marie Krantz, Heinz Zoller, Gerd Utermann, and Andreas R. Janecke
SIRT1 Markedly Extends Replicative Lifespan if the NAD+ Salvage Pathway Is Enhanced, Cynthia Ho, Eric van der Veer, Oula Akawi, and J. Geoffrey Pickering
Integrin-linked Kinase Interactions with ELMO2 Modulate Cell Polarity, Ernest Ho, Tames Irvine, Gregory J. A. Vilk, Gilles Lajoie, Kodi S. Ravichandran, Sudhir J. A. D'Souza, and Lina Dagnino
The Drosophila DHR96 Nuclear Receptor Binds Cholesterol and Regulates Cholesterol Homeostasis, Michael A. Horner, Keith Pardee, Suya Liu, Kirst King-Jones, Gilles Lajoie, Aled Edwards, Henry M. Krause, and Carl S. Thummel
Identification of a Novel Zn2+-binding Domain in the Autosomal Recessive Juvenile Parkinson-related E3 Ligase Parkin, Ventzislava A. Hristova, Steven A. Beasley, Jane Rylett, and Gary S. Shaw
Anti-Inflammatory and Renal Protective Actions of Stanniocalcin-1 in a Model of Anti-Glomerular Basement Membrane Glomerulonephritis, Luping Huang, Gabriela Garcia, Yahuan Lou, Qin Zhou, Luan D. Truong, Gabriel DiMattia, Xia Ru Lan, Hui Y. Lan, Yanlin Wang, and David Sheikh-Hamad
De Novo Sequencing Methods in Proteomics, Christopher Hughes, Bin Ma, and Gilles A. Lajoie
Cellular Localization and Allele-selective Inhibition of Mutant Huntingtin Protein by Peptide Nucleic Acid Oligomers Containing the Fluorescent Nucleobase [bis-o-(aminoethoxy)phenyl]pyrrolocytosine, Jiaxin Hu, David W. Dodd, Robert H. E. Hudson, and David R. Corey
Role of Phosphate Groups in Inhibition of Calcium Oxalate Crystal Growth by Osteopontin, Graeme K. Hunter, Bernd Grohe, Sara Jeffrey, Jason O'Young, Esben S. Sørensen, and Harvey A. Goldberg