Submissions from 2010
Regulation of Cell Proliferation and Survival: Convergence of Protein Kinases and Caspases, James S. Duncan, Jacob P. Turowec, Greg Vilk, Shawn S. C. Li, Gregory B. Gloor, and David W. Litchfield
Exercise Motivation: A Cross-sectional Analysis Examining Its Relationships with Frequency, Intensity, and Duration of Exercise, Lindsay R. Duncan, Craig R. Hall, Philip M. Wilson, and O. Jenny
IL-6 and TNFalpha across the Umbilical Circulation in Term Pregnancies: Relationship with Labour Events, Greg Duncombe, Ruud A. W. Veldhuizen, Robert J. Gratton, Victor K. M. Han, and Bryan S. Richardson
Mobile DNA Elements in T4 and Related Phages, David R. Edgell, Ewan A. Gibb, and Marlene Belfort
To Report or Not to Report: A Descriptive Study Exploring ICU Nurses' Perceptions of Error and Error Reporting, Sherry Espin, Abigail Wickson-Griffiths, Michelle Wilson, and Lorelei Lingard
Imaging of lung function using hyperpolarized helium-3 magnetic resonance imaging: Review of current and emerging translational methods and applications, Sean Fain, Mark L Schiebler, David G McCormack, and Grace Parraga
Mutual Information Is Critically Dependent on Prior Assumptions: Would the Correct Estimate of Mutual Information Please Identify Itself?, Andrew D. Fernandes and Gregory B. Gloor
Estimating the Evidence of Selection and the Reliability of Inference in Unigenic Evolution, Andrew D. Fernandes, Benjamin P. Kleinstiver, David R. Edgell, Lindi M. Wahl, and Gregory B. Gloor
Random Pharmacokinetic Profiles of EC-MPS in Children with Autoimmune Disease, Guido Filler, Ajay Parkash Sharma, Deborah M. Levy, and Abeer Yasin
Gaining Ground, Losing Ground: The Paradoxes of Rural Homelessness, Cheryl Forchuk, Phyllis Montgomery, Helene Berman, Catherine Ward-Griffin, Rick Csiernik, Carolyn Gorlick, Elsabeth Jensen, and Patrick Riesterer
A Medical Student's Perspective of Participation in an Interprofessional Education Placement: An Autoethnography, Jennifer Gallé and Lorelei Lingard
Perceived Facilitators of and Barriers to Healthful Eating among University Students, Alicia C. Garcia, Lesley Sykes, June Matthews, Noelle Martin, and Beverly Leipert
Perceived Facilitators of and Barriers to Healthful Eating Among University Students, Alicia C. Garcia, Lesley Sykes, June Matthews, Noelle Martin, and Beverly Leipert
Bioremediation and tolerance of humans to heavy metals through microbial processes: A potential role for probiotics?, Gregory B. Gloor, Ruben Hummelen, Jean M. Macklaim, Russell J. Dickson, Andrew D. Fernandes, Roderick MacPhee, and Gregor Reid
Microbiome Profiling by Illumina Sequencing of Combinatorial Sequence-Tagged PCR Products, Gregory B. Gloor, Ruben Hummelen, Jean M. Macklaim, Russell J. Dickson, Andrew D. Fernandes, Roderick MacPhee, and Gregor Reid
Functionally Compensating Coevolving Positions Are Neither Homoplasic Nor Conserved in Clades, Gregory B. Gloor, Gaurav Tyagi, Dana M. Abrassart, Andrew J. Kingston, Andrew D. Fernandes, Stanley D. Dunn, and Christopher J. Brandl
Multiple Epigenetic Modifiers Induce Aggressive Viral Extinction in Extraembryonic Endoderm Stem Cells, Michael C. Golding, Liyue Zhang, and Mellissa R. W. Mann
Studies of the Maltose Transport System Reveal a Mechanism for Coupling ATP Hydrolysis to Substrate Translocation without Direct Recognition of Substrate, Alister D. Gould and Brian H. Shilton
Rapid in Vivo Whole Body Composition of Rats Using Cone Beam µCT, Patrick V. Granton, Chris J. D. Norley, Joseph Umoh, Eva A. Turley, Bruce C. Frier, Earl G. Noble, and David W. Holdsworth
How Old Is This Mutation? A Study of Three Ashkenazi Jewish Founder Mutations, Celia M. T. Greenwood, Shuying Sun, Justin Veenstra, Nancy Hamel, Bethany Niell, Stephen Gruber, and William D. Foulkes
Credentials as Cultural Capital: The Pursuit of Higher Degrees among Academic Medical Trainees, Orlee R. Guttman and Lorelei Lingard
Migration of Periodontal Ligament Fibroblasts on Nanometric Topographical Patterns: Influence of Filopodia and Focal Adhesions on Contact Guidance, Douglas W. Hamilton, Christine J. Oates, Abdollah Hasanzadeh, and Silvia Mittler
Investigating Concordance in Diabetes Diagnosis between Primary Care Charts (Electronic Medical Records) and Health Administrative Data: A Retrospective Cohort Study, Stewart B. Harris, Richard H. Glazier, Jordan W. Tompkins, Andrew S. Wilton, Vijaya Chevendra, Moira A. Stewart, and Amardeep Thind
Optical Waveguides Formed by Silver Ion Exchange in Schott SG11 Glass for Waveguide Evanescent Field Fluorescence Microscopy: Evanescent Images of HEK293 Cells, Abdollah Hassanzadeh, Michael Nitsche, Souzan Armstrong, S. Jeffrey Dixon, Noushin Nabavi, Rene Harrison, Uwe Langbein, and Silvia Mittler
Genome-Wide Association Studies of Plasma Lipids: Have We Reached the Limit?, Robert A. Hegele
Advances in Stroke 2009: Update on the Genetics of Stroke and Cerebrovascular Disease 2009, Robert A. Hegele and Martin Dichgans
Activity of Protein Kinase CK2 Uncouples Bid Cleavage from Caspase-8 Activation, Christian T. Hellwig, Agnieszka H. Ludwig-Galezowska, Caoimhin G. Concannon, David W. Litchfield, Jochen H. M. Prehn, and Markus Rehm
Canadian Global Village Reality: Anthropometric Surrogate Cutoffs and Metabolic Abnormalities among Canadians of East Asian, South Asian, and European Descent, Meizi He, E. T. S. Li, Stewart Harris, Murray W. Huff, Chun Y. Yau, and G. Harvey Anderson
Screen-related Sedentary Behaviors: Children's and Parents' Attitudes, Motivations, and Practices, Meizi He, Leonard Piché, Charlene Beynon, and Stewart Harris
A Cancer Derived Mutation in the Retinoblastoma Gene with a Distinct Defect for LXCXE Dependent Interactions, Shauna A. Henley, Sarah M. Francis, Jordan Demone, Peter Ainsworth, and Frederick A. Dick
Kidney and Liver Transplants from Donors after Cardiac Death: Initial Experience at the London Health Sciences Centre, Roberto Hernandez-Alejandro, Yves Caumartin, Cameron Chent, Mark A. Levstik, Douglas Quan, Norman Muirhead, Andrew A. House, Vivian McAlister, Anthony M. Jevnikar, Patrick P. W. Luke, and William Wall
An Overlapping Kinase and Phosphatase Docking Site Regulates Activity of the Retinoblastoma Protein, Alexander Hirschi, Matthew Cecchini, Rachel C. Steinhardt, Michael R. Schamber, Frederick A. Dick, and Seth M. Rubin
Increased Blood Pressure and Hyperdynamic Cardiovascular Responses in Carriers of a Common Hyperfunctional Variant of Adenylyl Cyclase 6, Gary J. Hodges, Robert Gros, Robert A. Hegele, Stan Van Uum, J. Kevin Shoemaker, and Ross D. Feldman
Mutational Analysis of the C-terminal FATC Domain of Saccharomyces Cerevisiae Tra1, Stephen M. T. Hoke, A. Irina Mutiu, Julie Genereaux, Stephanie Kvas, Michael Buck, Michael Yu, Gregory B. Gloor, and Christopher J. Brandl
Dual-task Interference: The Effects of Verbal Cognitive Tasks on Upright Postural Stability in Parkinson's Disease, J. D. Holmes, M. E. Jenkins, Andrew M. Johnson, S. G. Adams, and S. J. Spaulding
Effect of B-Vitamin Therapy on Progression of Diabetic Nephropathy: A Randomized Controlled Trial, Andrew A. House, Misha Eliasziw, Daniel C. Cattran, David N. Churchill, Matthew J. Oliver, Adrian Fine, George K. Dresser, and J. David Spence
The Fibroblast Growth Factor Receptor Substrate 3 Adapter Is a Developmentally Regulated Microtubule-associated Protein Expressed in Migrating and Differentiated Neurons, Todd Hryciw, James I. S. MacDonald, Renée Phillips, Claudia Seah, Stephen Pasternak, and Susan O. Meakin
The Impact of Delays to Admission from the Emergency Department on Inpatient Outcomes, Qing Huang, Amardeep Thind, Jonathan F. Dreyer, and Gregory S. Zaric
Matrigel: A Complex Protein Mixture Required for Optimal Growth of Cell Culture, Chris S. Hughes, Lynne M. Postovit, and Gilles A. Lajoie
Can prebiotics and probiotics improve therapeutic outcomes for undernourished individuals?, Ruben Hummelen, Andrew D. Fernandes, Jean M. Macklaim, Russell J. Dickson, John Changalucha, Gregory B. Gloor, and Gregor Reid
Deep Sequencing of the Vaginal Microbiota of Women with HIV, Ruben Hummelen, Andrew D. Fernandes, Jean M. Macklaim, Russell J. Dickson, John Changalucha, Gregory B. Gloor, and Gregor Reid
Clinical study comparing probiotic Lactobacillus GR-1 and RC-14 with metronidazole vaginal gel to treat symptomatic bacterial vaginosis, Ruben Hummelen, Jaimie Hemsworth, and Gregor Reid
Characterization of the vaginal microbiota of healthy Canadian women through the menstrual cycle, Ruben Hummelen, Arjan P. Vos, Belinda Van'T Land, Klaske Van Norren, and Gregor Reid
Insulin-like Growth Factor Binding Protein-6 (IGFBP-6) Interacts with DNA-end Binding Protein Ku80 to Regulate Cell Fate, Cristiana Iosef, Gregory Vilk, Theofanis Gkourasas, Kyung-Jong Lee, Benjamin P. C. Chen, Ping Fu, Leon A. Bach, Gilles Lajoie, Madhulika B. Gupta, Shawn S. C. Li, and Victor K. Han
Cluster analysis of genotypically characterized Lactobacillus species based on physicochemical cell surface properties and their relationship with adhesion to hexadecane, Stephanie L. Irvine, Ruben Hummelen, Sharareh Hekmat, Caspar W. N. Looman, J. Dik F. Habbema, and Gregor Reid
A New Way of Relating: Perceptions Associated with a Team-based Error Disclosure Simulation Intervention, Lianne Jeffs, Sherry Espin, Sarah E. Shannon, Wendy Levinson, Melanie Kazman Kohn, and Lorelei Lingard
Predictive Validity of the UPDRS Postural Stability Score and the Functional Reach Test, When Compared with Ecologically Valid Reaching Tasks, M. E. Jenkins, Andrew M. Johnson, J. D. Holmes, F. F. Stephenson, and S. J. Spaulding
A Novel Mechanism of Cell Growth Regulation by Cell Cycle and Apoptosis Regulatory Protein (CARP)-1, Yan Jiang, Vineshkumar T Puliyappadamba, Liyue Zhang, Wenjuan Wu, Anil Wali, Michael B. Yaffe, Joseph A. Fontana, and Arun K. Rishi
Rare ATGL Haplotypes Are Associated with Increased Plasma Triglyceride Concentrations in the Greenland Inuit, Christopher T. Johansen, Zane R. Gallinger, Jian Wang, Matthew R. Ban, T. Kue Young, Peter Bjerregaard, and Robert A. Hegele
Translating Genomic Analyses into Improved Management of Coronary Artery Disease, Christopher T. Johansen, Matthew B. Lanktree, and Robert A. Hegele
Excess of Rare Variants in Genes Identified by Genome-wide Association Study of Hypertriglyceridemia, Christopher T. Johansen, Jian Wang, Matthew B. Lanktree, Henian Cao, Adam D. McIntyre, Matthew R. Ban, Rebecca A. Martins, Brooke A. Kennedy, Reina G. Hassell, Maartje E. Visser, Stephen M. Schwartz, Benjamin F. Voight, Roberto Elosua, Veikko Salomaa, Christopher J. O'Donnell, Geesje M. Dallinga-Thie, Sonia S. Anand, Salim Yusuf, Murray W. Huff, Sekar Kathiresan, and Robert A. Hegele
In Vivo Detection of PARACEST Agents with Relaxation Correction, Craig K. Jones, Alex X. Li, Mojmír Suchý, Robert H. E. Hudson, Ravi S. Menon, and Robert Bartha
EBP1 Is a Novel E2F Target Gene Regulated by Transforming Growth Factor-β, David Judah, Wing Y. Chang, and Lina Dagnino
Loops Govern SH2 Domain Specificity by Controlling Access to Binding Pockets, Tomonori Kaneko, Haiming Huang, Bing Zhao, Lei Li, Huadong Liu, Courtney K. Voss, Chenggang Wu, Martin R. Schiller, and Shawn Shun-Cheng Li
Mammalian Numb-interacting Protein 1/Dual Oxidase Maturation Factor 1 Directs Neuronal Fate in Stem Cells, Karen A. M. Kennedy, Elena A. Ostrakhovitch, Shelley D. E. Sandiford, Thamara Dayarathna, Xiaojun Xie, Elaine Y. L. Waese, Wing Y. Chang, Qingping Feng, Ilona S. Skerjanc, William L. Stanford, and Shawn S. C. Li
ATRX Partners with Cohesin and MeCP2 and Contributes to Developmental Silencing of Imprinted Genes in the Brain, Kristin D. Kernohan, Yan Jiang, Deanna C. Tremblay, Anne C. Bonvissuto, James H. Eubanks, Mellissa R. W. Mann, and Nathalie G. Bérubé
Differential Cytokine Regulation by NF-κB and AP-1 in Jurkat T-cells, Hazem Khalaf, Jana Jass, and Per-Erik Olsson
Omalizumab: Practical Considerations Regarding the Risk of Anaphylaxis, Harold L. Kim, Richard Leigh, and Allan Becker
Chronic obstructive pulmonary disease: Longitudinal hyperpolarized (3)He MR imaging, Miranda Kirby, Lindsay Mathew, Andrew Wheatley, Giles E Santyr, David G McCormack, and Grace Parraga
A Unified Genetic, Computational and Experimental Framework Identifies Functionally Relevant Residues of the Homing Endonuclease I-BmoI, Benjamin P. Kleinstiver, Andrew D. Fernandes, Gregory B. Gloor, and David R. Edgell
Laminar Flow Effects During Laser-Induced Oxidative Labeling for Protein Structural Studies by Mass Spectrometry, Lars Konermann, Bradley B. Stocks, and Tomasz Czarny
Mass Spectrometry Combined with Oxidative Labeling for Exploring Protein Structure and Folding, Lars Konermann, Bradley B. Stocks, Yan Pan, and Xin Tong
Toenail Selenium Status and DNA Repair Capacity among Female BRCA1 Mutation Carriers, Joanne Kotsopoulos, Zhou Chen, Katherine A. Vallis, Aletta Poll, Parviz Ghadirian, Greg Kennedy, Peter Ainsworth, and Steven A. Narod
Can bacterial interference prevent infection?, Tara Koyama, Pirkka V. Kirjavainen, Cale Fisher, Kingsley Anukam, Kelly Summers, Sharareh Hekmat, and Gregor Reid
Predictors of Pneumococcal Vaccination among Older Adults with Pneumonia: Findings from the Community Acquired Pneumonia Impact Study, Paul Krueger, Oona St. Amant, and Mark Loeb
APOC1 T45S Polymorphism Is Associated with Reduced Obesity Indices and Lower Plasma Concentrations of Leptin and Apolipoprotein C-I in Aboriginal Canadians, Piya Lahiry, Henian Cao, Matthew R. Ban, Rebecca L. Pollex, Mary Mamakeesick, Bernard Zinman, Stewart B. Harris, Anthony J. G. Hanley, Murray W. Huff, Philip W. Connelly, and Robert A. Hegele
Kinase Mutations in Human Disease: Interpreting Genotype-phenotype Relationships, Piya Lahiry, Ali Torkamani, Nicholas J. Schork, and Robert A. Hegele
Comprehensive Analysis of Genomic Variation in the LPA Locus and Its Relationship to Plasma Lipoprotein(a) in South Asians, Chinese, and European Caucasians, Matthew B. Lanktree, Sonia S. Anand, Salim Yusuf, Robert A. Hegele, and SHARE Investigators
Advances in Genomic Analysis of Stroke: What Have We Learned and Where Are We Headed?, Matthew B. Lanktree, Martin Dichgans, and Robert A. Hegele
Phenomics: Expanding the Role of Clinical Evaluation in Genomic Studies, Matthew B. Lanktree, Reina G. Hassell, Piya Lahiry, and Robert A. Hegele
Extremes of Unexplained Variation as a Phenotype: An Efficient Approach for Genome-Wide Association Studies of Cardiovascular Disease, Matthew B. Lanktree, Robert A. Hegele, Nicholas J. Schork, and J. David Spence
Genetic Variation in Hyaluronan Metabolism Loci Is Associated with Plasma Plasminogen Activator Inhibitor-1 Concentration, Matthew B. Lanktree, Christopher T. Johansen, Sonia S. Anand, A. Darlene Davis, Ruby Miller, Salim Yusuf, Robert A. Hegele, SHARE, and SHARE-AP Investigators
A Translational View of the Genetics of Lipodystrophy and Ectopic Fat Deposition, Matthew B. Lanktree, Christopher T. Johansen, Tisha R. Joy, and Robert A. Hegele
Lysophosphatidic Acid Signals through Multiple Receptors in Osteoclasts to Elevate Cytosolic Calcium Concentration, Evoke Retraction, and Promote Cell Survival, Danielle M. Lapierre, Natsuko Tanabe, Alexey Pereverzev, Martha Spencer, Ryan P. P. Shugg, S. Jeffrey Dixon, and Stephen M. Sims
New Graduate Burnout: The Impact of Professional Practice Environment, Workplace Civility, and Empowerment, Heather K. S. Laschinger, Joan Finegan, and Piotr Wilk
Towards a Comprehensive Theory of Nurse/Patient Empowerment: Applying Kanter's Empowerment Theory to Patient Care, Heather K. Spence Laschinger, Stephanie Gilbert, Lesley M. Smith, and Kate Leslie
New Graduate Nurses’ Experiences of Bullying and Burnout in Hospital Settings, Heather K. Spence Laschinger, Ashley L. Grau, Joan Finegan, and Piotr Wilk
Towards an Anti-fibrotic Therapy for Scleroderma: Targeting Myofibroblast Differentiation and Recruitment, Andrew Leask
Association of Apolipoprotein B with Incident Type 2 Diabetes in an Aboriginal Canadian Population, Sylvia H. Ley, Stewart B. Harris, Philip W. Connelly, Mary Mamakeesick, Joel Gittelsohn, Thomas M. Wolever, Robert A. Hegele, Bernard Zinman, and Anthony J. Hanley
Assessing the Association of the HNF1A G319S Variant with C-reactive Protein in Aboriginal Canadians: A Population-based Epidemiological Study, Sylvia H. Ley, Robert A. Hegele, Philip W. Connelly, Stewart B. Harris, Mary Mamakeesick, Henian Cao, Joel Gittelsohn, Ravi Retnakaran, Bernard Zinman, and Anthony J. Hanley
Nerve Growth Factor Activation of the TrkA Receptor Induces Cell Death, by Macropinocytosis, in Medulloblastoma Daoy Cells, Chunhui Li, James I. S. Macdonald, Todd Hryciw, and Susan O. Meakin
Systematic Identification of Methyllysine-Driven Interactions for Histone and Nonhistone Targets, Huadong Liu, Marek Galka, Aimee Iberg, Zezhou Wang, Lei Li, Courtney Voss, Xinfeng Jiang, Gilles Lajoie, Zhiping Huang, Mark T. Bedford, and Shawn S. C. Li
Temtamy Preaxial Brachydactyly Syndrome Is Caused by Loss-of-Function Mutations in Chondroitin Synthase 1, a Potential Target of BMP Signaling, Yun Li, Kathrin Laue, Samia Temtamy, Mona Aglan, L. Damla Kotan, Gökhan Yigit, Husniye Canan, Barbara Pawlik, Gudrun Nürnberg, Emma L. Wakeling, Oliver W. Quarrell, Ingelore Baessmann, Matthew B. Lanktree, Mustafa Yilmaz, Robert A. Hegele, Khalda Amr, Klaus W. May, Peter Nürnberg, A. Kemal Topaloglu, Matthias Hammerschmidt, and Bernd Wollnik
Cross-modal Plasticity in Specific Auditory Cortices Underlies Visual Compensations in the Deaf, Stephen G. Lomber, M. Alex Meredith, and Andrej Kral
Rapid and Direct Transport of Cell Surface APP to the Lysosome Defines a Novel Selective Pathway, Angela Lorenzen, Jonathan Samosh, Kenneth Vandewark, Pieter H. Anborgh, Claudia Seah, Ana C. Magalhaes, Sean P. Cregan, Stephen S. G. Ferguson, and Stephen H. Pasternak
Independent Mechanisms of Stimulation of Polynucleotide Kinase/Phosphatase by Phosphorylated and Non-phosphorylated XRCC1, Meiling Lu, Rajam S. Mani, Feridoun Karimi-Busheri, Mesfin Fanta, Hailin Wang, David W. Litchfeld, and Michael Weinfeld
Cerebral Protein Synthesis in the Ovine Fetus Near Term with Amino Acid Infusion and Insulin-Induced Hypoaminoacidemia., James N. Maclachlan, Jeremy D. McCallum, Norman Smith, Brad Matushewski, and Bryan S. Richardson
Biomaterials used in urology: Current issues of biocompatibility, infection, and encrustation, Roderick A. MacPhee, Ruben Hummelen, Jordan E. Bisanz, Wayne L. Miller, and Gregor Reid
Preferences for Active and Aggressive Intervention among Patients with Advanced Cancer, Vincent Maida, Jonathan Peck, Marguerite Ennis, Navjot Brar, and Alexandria R. Maida
Kindled Seizure in the Prefrontal Cortex Activated Behavioral Hyperactivity and Increase in Accumbens Gamma Oscillations through the Hippocampus, Jingyi Ma and L. Stan Leung
Dual Modes of Interaction between XRCC4 and Polynucleotide Kinase/Phosphatase: Implications for Nonhomologous End Joining, Rajam S. Mani, Yaping Yu, Shujuan Fang, Meiling Lu, Mesfin Fanta, Angela E. Zolner, Nasser Tahbaz, Dale A. Ramsden, David W. Litchfield, Susan P. Lees-Miller, and Michael Weinfeld
Side-by-Side Comparison of Five Commercial Media Systems in a Mouse Model: Suboptimal In Vitro Culture Interferes with Imprint Maintenance, B. A. Market-Velker, A. D. Fernandes, and M. R. W. Mann
Dual Effects of Superovulation: Loss of Maternal and Paternal Imprinted Methylation in a Dose-dependent Manner, Brenna A. Market-Velker, Liyue Zhang, Lauren S. Magri, Anne C. Bonvissuto, and Mellissa R. W. Mann
Codon Optimization for Enhanced Escherichia Coli Expression of Human S100A11 and S100A1 Proteins, Nicole M. Marlatt, Donald E. Spratt, and Gary S. Shaw
Photovoice and Its Potential Use In Nutrition and Dietetic Research, Noelle Martin, Alicia C. Garcia, and Beverly Leipert
Detection of longitudinal lung structural and functional changes after diagnosis of radiation-induced lung injury using hyperpolarized 3He magnetic resonance imaging, Lindsay Mathew, Stewart Gaede, Andrew Wheatley, Roya Etemad-Rezai, George B Rodrigues, and Grace Parraga
The Effects of Oligomerization on Saccharomyces cerevisiae Mcm4/6/7 Function, Xiaoli Ma, Brent E. Stead, Atoosa Rezvanpour, and Megan J. Davey
Hypertonic Saline for Peri-operative Fluid Management, Vivian McAlister, Karen E. A. Burns, Tammy Znajda, and Brian Church
Song: I'll Repair for You, Derek T. McLachlin
An Institutional Solution to Conflicts of Conscience in Medicine, Carolyn McLeod