Clinical study comparing probiotic Lactobacillus GR-1 and RC-14 with metronidazole vaginal gel to treat symptomatic bacterial vaginosis

Authors

Ruben Hummelen, Erasmus MC
Jaimie Hemsworth, Brescia University College
Gregor Reid, Lawson Health Research Institute

Document Type

Article

Publication Date

1-1-2010

Journal

Nutrients

Volume

2

Issue

6

First Page

626

Last Page

651

URL with Digital Object Identifier

10.3390/nu2060626

Abstract

Low serum concentrations of micronutrients, intestinal abnormalities, and an inflammatory state have been associated with HIV progression. These may be ameliorated by micronutrients, N-acetyl cysteine, probiotics, and prebiotics. This review aims to integrate the evidence from clinical trials of these interventions on the progression of HIV. Vitamin B, C, E, and folic acid have been shown to delay the progression of HIV. Supplementation with selenium, N-acetyl cysteine, probiotics, and prebiotics has considerable potential, but the evidence needs to be further substantiated. Vitamin A, iron, and zinc have been associated with adverse effects and caution is warranted for their use. © 2010 by the authors, licensee MDPI, Basel, Switzerland.