Paediatrics Publications

 

Research in The Department of Paediatrics at Schulich School of Medicine & Dentistry is divided into eighteen areas of focus. These areas include cardiology, child development, critical care medicine, endocrinology/diabetes, genetics/metabolics, infectious disease, and neurology.

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Submissions from 2014

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PPAR ligands improve impaired metabolic pathways in fetal hearts of diabetic rats, Melisa Kurtz, Evangelina Capobianco, Nora Martinez, Sabrina Lorena Roberti, Edith Arany, and Alicia Jawerbaum

Do obese children experience more severe fractures than nonobese children? A cross-sectional study from a paediatric emergency department, Charisse Kwan, Quynh Doan, John Paul Oliveria, Melissa Ouyang, Andrew Howard, and Kathy Boutis

The JDRF CCTN CGM TIME Trial: Timing of Initiation of continuous glucose Monitoring in Established pediatric type 1 diabetes: Study protocol, recruitment and baseline characteristics, Margaret L. Lawson, Brenda Bradley, Karen McAssey, Cheril Clarson, Susan E. Kirsch, Farid H. Mahmud, Jacqueline R. Curtis, Christine Richardson, Jennilea Courtney, Tammy Cooper, Cynthia J. Downie, Gopalan Rajamannar, and Nicholas Barrowman

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Rac1 signaling is critical to cardiomyocyte polarity and embryonic heart development, Carmen Leung, Xiangru Lu, Murong Liu, and Qingping Feng

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ATRX promotes gene expression by facilitating transcriptional elongation through guanine-rich coding regions, Michael A. Levy, Kristin D. Kernohan, Yan Jiang, and Nathalie G. Bérubé

Infantile sialic acid storage disease: Two unrelated inuit cases homozygous for a common novel SLC17A5 mutation, Matthew A. Lines, C. Anthony Rupar, Jack W. Rip, Berivan Baskin, Peter N. Ray, Robert A. Hegele, David Grynspan, Jean Michaud, and Michael T. Geraghty

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Nitric oxide synthase-3 deficiency results in hypoplastic coronary arteries and postnatal myocardial infarction, Yin Liu, Xiangru Lu, Fu Li Xiang, Robert E. Poelmann, Adriana C. Gittenberger-De Groot, Jeffrey Robbins, and Qingping Feng

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Choline kinase beta is required for normal endochondral bone formation, Zhuo Li, Gengshu Wu, Roger B. Sher, Zohreh Khavandgar, Martin Hermansson, Gregory A. Cox, Michael R. Doschak, Monzur Murshed, Frank Beier, and Dennis E. Vance

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Severe methylenetetrahydrofolate reductase deficiency: Clinical clues to a potentially treatable cause of adult-onset hereditary spastic paraplegia, Alexander Lossos, Omri Teltsh, Tsipi Milman, Vardiella Meiner, Rima Rozen, Daniel Leclerc, Bernd C. Schwahn, and Natalya Karp

Exercise Counseling to Enhance Smoking Cessation Outcomes: The Fit2Quit Randomized Controlled Trial, Ralph Maddison, Vaughan Roberts, Hayden McRobbie, Christopher Bullen, Harry Prapavessis, Marewa Glover, Yannan Jiang, Paul Brown, William Leung, Sue Taylor, and Midi Tsai

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Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy: Executive Summary, Laura A. Magee, Anouk Pels, Michael Helewa, Evelyne Rey, Peter von Dadelszen, Francois Audibert, Emmanuel Bujold, Anne Marie Côté, Myrtle Joanne Douglas, Genevieve Eastabrook, Tabassum Firoz, Paul Gibson, Andrée Gruslin, Jennifer Hutcheon, Gideon Koren, Ian Lange, Line Leduc, and Alexander G. Logan

NLRP7 affects trophoblast lineage differentiation, binds to overexpressed YY1 and alters cpg methylation, Sangeetha Mahadevan, Shu Wen, Ying Wooi Wan, Hsiu Huei Peng, Subhendu Otta, Zhandong Liu, Michelina Iacovino, Elisabeth M. Mahen, Michael Kyba, Bekim Sadikovic, and Ignatia B. Van den Veyver

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Prostaglandin E2 receptor EP4 as the common target on cancer cells and macrophages to abolish angiogenesis, lymphangiogenesis, metastasis, and stem-like cell functions., Mousumi Majumder, Xiping Xin, Ling Liu, Gannareddy V. Girish, and Peeyush K. Lala

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Intra-abdominal mass and iron deficiency anemia in a 15-year-old boy: Case report and literature review, Kathryn Martin, Heather Emmerton-Coughlin, and Andreana Butter

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An exploration of Early Childhood Education students' knowledge and preparation to facilitate physical activity for preschoolers: A cross-sectional study, Olivia Jm Martyniuk and Patricia Tucker

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Lentivector integration sites in ependymal cells from a model of metachromatic leukodystrophy: Non-b dna as a new factor influencing integration, Robert G. McAllister, Jiahui Liu, Matthew W. Woods, Sean K. Tom, Anthony Rupar, and Stephen D. Barr

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Maternal, umbilical arterial and umbilical venous 25-hydroxyvitamin D and adipocytokine concentrations in pregnancies with and without gestational diabetes, Ruth McManus, Kelly Summers, Barbra De Vrijer, Nicole Cohen, Alexandra Thompson, and Isabelle Giroux

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Quantitative tissue pH measurement during cerebral ischemia using amine and amide concentration-independent detection (AACID) with MRI, Nevin McVicar, Alex X. Li, Daniela F. Gonçalves, Miranda Bellyou, Susan O. Meakin, Marco A.M. Prado, and Robert Bartha

Epigenetic reprogramming in Mist1-/- mice predicts the molecular response to cerulein-induced pancreatitis, Rashid Mehmood, Gabor Varga, Sonali Q. Mohanty, Scott W. Laing, Yuefeng Lu, Charis L. Johnson, Alexei Kharitonenkov, and Christopher L. Pin

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Case 3: Stridor and cough in a young child, Shruti Mehrotra, Jennifer Kilgar, and Rodrick Lim

The effects of olanzapine on genome-wide DNA methylation in the hippocampus and cerebellum, Melkaye G. Melka, Benjamin I. Laufer, Patrick McDonald, Christina A. Castellani, Nagalingam Rajakumar, Richard O'Reilly, and Shiva M. Singh

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N-Acetylcysteine prevents congenital heart defects induced by pregestational diabetes, Hoda Moazzen, Xiangru Lu, Noelle L. Ma, Thomas J. Velenosi, Brad L. Urquhart, Lambertus J. Wisse, Adriana C. Gittenberger-de Groot, and Qingping Feng

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Infrared thermography to assess proliferation and involution of infantile hemangiomas: A prospective cohort study, Javed Ayoub Mohammed, Alexandra Balma-Mena, Ajith Chakkittakandiyil, Florentina Matea, and Elena Pope

Ontogeny of human hepatic and intestinal transporter gene expression during childhood: Age matters, Miriam G. Mooij, Ute I. Schwarz, Barbara A.E. De Koning, J. Steven Leeder, Roger Gaedigk, Janneke N. Samsom, Edwin Spaans, and Johannes B. Van Goudoever

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Health related quality of life measure in systemic pediatric rheumatic diseases and its translation to different languages: An international collaboration, Nandini N. Moorthy, Elizabeth Roy, Vamsi Kurra, Margaret G.E. Peterson, Afton L. Hassett, Thomas J.A. Lehman, Christiaan Scott, Dalia El-Ghoneimy, Shereen Saad, Reem El Feky, Sulaiman Al-Mayouf, Pavla Dolezalova, Hana Malcova, Troels Herlin, Susan Nielsen, Nico Wulffraat, Annet van Royen, Stephen D. Marks, Alexandre Belot, Jurgen Brunner, Christian Huemer, Ivan Foeldvari, Gerd Horneff, Traudel Saurenman, Silke Schroeder, Polyxeni Pratsidou-Gertsi, Maria Trachana, Yosef Uziel, and Amita Aggarwal