Paediatrics Publications

 

Research in The Department of Paediatrics at Schulich School of Medicine & Dentistry is divided into eighteen areas of focus. These areas include cardiology, child development, critical care medicine, endocrinology/diabetes, genetics/metabolics, infectious disease, and neurology.

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Submissions from 2015

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Treatment of young children with CNS-positive acute lymphoblastic leukemia without cranial radiotherapy, Marta Wilejto, Giancarlo Di Giuseppe, Johann Hitzler, Sumit Gupta, and Oussama Abla

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Collaborative public health system interventions for chronic disease prevention among Urban Aboriginal peoples, Piotr Wilk and Martin Cooke

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Estimation of GFR using β-trace protein in children, Samantha H. Witzel, Shih Han S. Huang, Branko Braam, and Guido Filler

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Adverse effects of perinatal nicotine exposure on reproductive outcomes, Michael K. Wong, Nicole G. Barra, Nadia Alfaidy, Daniel B. Hardy, and Alison C. Holloway

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Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential, Daniel L. Worthley, Michael Churchill, Jocelyn T. Compton, Yagnesh Tailor, Meenakshi Rao, Yiling Si, Daniel Levin, Matthew G. Schwartz, Aysu Uygur, Yoku Hayakawa, Stefanie Gross, Bernhard W. Renz, Wanda Setlik, Ashley N. Martinez, Xiaowei Chen, Saqib Nizami, Heon Goo Lee, H. Paco Kang, Jon Michael Caldwell, Samuel Asfaha, C. Benedikt Westphalen, Trevor Graham, Guangchun Jin, Karan Nagar, Hongshan Wang, Mazen A. Kheirbek, Alka Kolhe, Jared Carpenter, and Mark Glaire

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The process, outcomes, and challenges of feasibility studies conducted in partnership with stakeholders: A health intervention for women survivors of intimate partner violence, Judith Wuest, Marilyn Merritt-Gray, Norma Dubé, Marilyn J. Hodgins, Jeannie Malcolm, Jo Ann Majerovich, Kelly Scott-Storey, Marilyn Ford-Gilboe, and Colleen Varcoe

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Normal renal sonogram identifies renal colic patients at low risk for urologic intervention: A prospective cohort study, Justin W. Yan, Shelley L. McLeod, Marcia L. Edmonds, Robert J. Sedran, and Karl D. Theakston

In vivo imaging of human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice, Kazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim, Erin G. Tirona, R. H.J. Mathijssen, and A. Sparreboom

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Long-term clinical outcomes of repeat hysteroscopic endometrial ablation after failed hysteroscopic endometrial ablation, Grace W. Yeung, George A. Vilos, Angelos G. Vilos, Ayman Oraif, Hanin Abduljabar, and Basim Abu-Rafea

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Thyroid hormone receptor regulates most genes independently of fibroblast growth factor 21 in liver, Aijun Zhang, Douglas H. Sieglaff, Jean Philippe York, Ji Ho Suh, Stephen D. Ayers, Glenn E. Winnier, Alexei Kharitonenkov, Christopher Pin, Pumin Zhang, Paul Webb, and Xuefeng Xia

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Potential complementary therapy for adverse drug reactions to sulfonamides: Chemoprotection against oxidative and nitrosative stress by TCM constituents and defined mixtures, Lei Zhang, Dao Feng Chen, Xue Yan Xia, Cindy Yip, Michael J. Rieder, and John R. Bend

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Placental adaptations in growth restriction, Song Zhang, Timothy R.H. Regnault, Paige L. Barker, Kimberley J. Botting, Isabella C. McMillen, Christine M. McMillan, Claire T. Roberts, and Janna L. Morrison

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Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease, Qing Zhou, Hongying Wang, Daniella M. Schwartz, Monique Stoffels, Yong Hwan Park, Yuan Zhang, Dan Yang, Erkan Demirkaya, Masaki Takeuchi, Wanxia Li Tsai, Jonathan J. Lyons, Xiaomin Yu, Claudia Ouyang, Celeste Chen, David T. Chin, Kristien Zaal, Settara C. Chandrasekharappa, Eric P. Hanson, Zhen Yu, James C. Mullikin, Sarfaraz A. Hasni, Ingrid E. Wertz, Amanda K. Ombrello, Deborah L. Stone, Patrycja Hoffmann, Anne Jones, Beverly K. Barham, Helen L. Leavis, and Annet Van Royen-Kerkof

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A dominantly-inherited Behcet-like disorder caused by haploinsufficiency of the TNFAIP3/A20 protein, Q. Zhou, H. Wang, J. Chae, D. Yang, E. Demirkaya, M. Stoffels, M. Takeuchi, C. Chen, A. Ombrello, D. Schwartz, P. Hoffmann, D. Stone, R. Laxer, A. V. Royen-Kerkhof, S. Ozen, M. Gadina, D. Kastner, and I. Aksentijevich

Submissions from 2014

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Familiarity with radiation exposure dose from diagnostic imaging for acute pulmonary embolism and current patterns of practice, Justin S. Ahn, Marcia L. Edmonds, Shelley L. McLeod, and Jonathan F. Dreyer

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Population Pharmacokinetic Study of Benznidazole in Pediatric Chagas Disease Suggests Efficacy despite Lower Plasma Concentrations than in Adults, Jaime Altcheh, Guillermo Moscatelli, Guido Mastrantonio, Samanta Moroni, Norberto Giglio, Maria Elena Marson, Griselda Ballering, Margarita Bisio, Gideon Koren, and Facundo García-Bournissen

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Recommendations for HLA-B15:02 and HLA-A31:01 genetic testing to reduce the risk of carbamazepine-induced hypersensitivity reactions, Ursula Amstutz, Neil H. Shear, Michael J. Rieder, Soomi Hwang, Vincent Fung, Hidefumi Nakamura, Mary B. Connolly, Shinya Ito, and Bruce C. Carleton

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Laparoscopic removal of an occult foreign body causing penetrating abdominal trauma in a child, Ram V. Anantha, Rodrick K. Lim, and Neil H. Merritt

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T helper type 2-polarized invariant natural killer T cells reduce disease severity in acute intra-abdominal sepsis, R. V. Anantha, D. M. Mazzuca, S. X. Xu, S. A. Porcelli, D. D. Fraser, C. M. Martin, I. Welch, T. Mele, S. M.M. Haeryfar, and J. K. Mccormick

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Erratum to: Race, ethnicity, and the duration of untreated psychosis: a systematic review (Soc Psychiatry Psychiatr Epidemiol, DOI 10.1007/s00127-013-0786-8), Kelly K. Anderson, Nina Flora, Suzanne Archie, Craig Morgan, and Kwame McKenzie

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The role of untreated psychosis in neurodegeneration: A review of hypothesized mechanisms of neurotoxicity in first-episode psychosis, Kelly K. Anderson, Aristotle Voineskos, Benoit H. Mulsant, Tony P. George, and Kwame J. McKenzie

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A meta-analysis of ethnic differences in pathways to care at the first episode of psychosis, K. K. Anderson, N. Flora, S. Archie, C. Morgan, and K. Mckenzie

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A transgenic zebrafish model expressing KIT-D816V recapitulates features of aggressive systemic mastocytosis, Tugce B. Balci, Sergey V. Prykhozhij, Evelyn M. Teh, Sahar I. Da'as, Eileen Mcbride, Robert Liwski, Ian C. Chute, Daniel Leger, Stephen M. Lewis, and Jason N. Berman

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Determinants of gross motor function of young children with cerebral palsy: A prospective cohort study, Doreen J. Bartlett, Lisa A. Chiarello, Sarah W. Mccoy, Robert J. Palisano, Lynn Jeffries, Alyssa L. Fiss, Peter Rosenbaum, and Piotr Wilk

Targeting the extracellular matrix: Matricellular proteins regulate cell-extracellular matrix communication within distinct niches of the intervertebral disc, Jake Bedore, Andrew Leask, and Cheryle A. Séguin