Paediatrics Publications
Research in The Department of Paediatrics at Schulich School of Medicine & Dentistry is divided into eighteen areas of focus. These areas include cardiology, child development, critical care medicine, endocrinology/diabetes, genetics/metabolics, infectious disease, and neurology.
Submissions from 2015
Obstetrical anal sphincter injuries (OASIS): Prevention, recognition, and repair, Marie Andrée Harvey, Marianne Pierce, Walter Jens-Erik, Queena Chou, Phaedra Diamond, Annette Epp, Roxana Geoffrion, Annick Larochelle, Kenny Maslow, Neustaedter Grace, Dante Pascali, Jane Schulz, David Wilkie, Sultan Abdul, and Thakar Ranee
Obstetrical Anal Sphincter Injuries (OASIS): Prevention, Recognition, and Repair, Marie Andrée Harvey, Marianne Pierce, Jens Erik Walter, Queena Chou, Phaedra Diamond, Annette Epp, Roxana Geoffrion, Annick Larochelle, Kenny Maslow, Grace Neustaedter, Dante Pascali, Jane Schulz, David Wilkie, Abdul Sultan, and Ranee Thakar
Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche, Yoku Hayakawa, Hiroshi Ariyama, Jitka Stancikova, Kosuke Sakitani, Samuel Asfaha, Bernhard W. Renz, Zinaida A. Dubeykovskaya, Wataru Shibata, Hongshan Wang, Christoph B. Westphalen, Xiaowei Chen, Yoshihiro Takemoto, Woosook Kim, Shradha S. Khurana, Yagnesh Tailor, Karan Nagar, Hiroyuki Tomita, Akira Hara, Antonia R. Sepulveda, Wanda Setlik, Michael D. Gershon, Subhrajit Saha, Lei Ding, Zeli Shen, James G. Fox, Richard A. Friedman, Stephen F. Konieczny, Daniel L. Worthley, and Vladimir Korinek
CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis, Yoku Hayakawa, Guangchun Jin, Hongshan Wang, Xiaowei Chen, Christoph B. Westphalen, Samuel Asfaha, Bernhard W. Renz, Hiroshi Ariyama, Zinaida A. Dubeykovskaya, Yoshihiro Takemoto, Yoomi Lee, Ashlesha Muley, Yagnesh Tailor, Duan Chen, Sureshkumar Muthupalani, James G. Fox, Arthur Shulkes, Daniel L. Worthley, Shigeo Takaishi, and Timothy C. Wang
Periostin conditions the matrix to generate a niche for islet regeneration, David A. Hess
Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids, Ling Huang, Audrey Holtzinger, Ishaan Jagan, Michael Begora, Ines Lohse, Nicholas Ngai, Cristina Nostro, Rennian Wang, Lakshmi B. Muthuswamy, Howard C. Crawford, Cheryl Arrowsmith, Steve E. Kalloger, Daniel J. Renouf, Ashton A. Connor, Sean Cleary, David F. Schaeffer, Michael Roehrl, Ming Sound Tsao, Steven Gallinger, Gordon Keller, and Senthil K. Muthuswamy
Tracking the brain’s functional coupling dynamics over development, R. Matthew Hutchison and J. Bruce Morton
The association between traumatic brain injury and ADHD in a Canadian adult sample, Gabriela Ilie, Evelyn R. Vingilis, Robert E. Mann, Hayley Hamilton, Maggie Toplak, Edward M. Adlaf, Nathan Kolla, Anca Ialomiteanu, Mark van der Mass, Mark Asbridge, Larissa Vingilis-Jaremko, Jürgen Rehm, and Michael D. Cusimano
Temperament and Objectively Measured Physical Activity and Sedentary Time among Canadian Preschoolers, Jennifer D. Irwin, Andrew M. Johnson, Leigh M. Vanderloo, Shauna M. Burke, and Patricia Tucker
Conditional haploinsufficiency of the retinoblastoma tumor suppressor gene, Charles A. Ishak and Frederick A. Dick
An ELMO2-RhoG-ILK network modulates microtubule dynamics, Bradley C. Jackson, Iordanka A. Ivanova, and Lina Dagnino
PMPCA mutations cause abnormal mitochondrial protein processing in patients with non-progressive cerebellar ataxia, Rebekah K. Jobling, Mirna Assoum, Oleksandr Gakh, Susan Blaser, Julian A. Raiman, Cyril Mignot, Emmanuel Roze, Alexandra Dürr, Alexis Brice, Nicolas Lévy, Chitra Prasad, Tara Paton, Andrew D. Paterson, Nicole M. Roslin, Christian R. Marshall, Jean Pierre Desvignes, Nathalie Roëckel-Trevisiol, Stephen W. Scherer, Guy A. Rouleau, André Mégarbané, Grazia Isaya, Valérie Delague, and Grace Yoon
Inhibition of pluripotency networks by the Rb tumor suppressor restricts reprogramming and tumorigenesis, Michael S. Kareta, Laura L. Gorges, Sana Hafeez, Bérénice A. Benayoun, Samuele Marro, Anne Flore Zmoos, Matthew J. Cecchini, Damek Spacek, Luis F.Z. Batista, Megan O'Brien, Yi Han Ng, Cheen Euong Ang, Dedeepya Vaka, Steven E. Artandi, Frederick A. Dick, Anne Brunet, Julien Sage, and Marius Wernig
Retinoic acid and the development of the endoderm, Gregory M. Kelly and Thomas A. Drysdale
Scoping review of patient- and family-oriented outcomes and measures for chronic pediatric disease, Sara D. Khangura, Maria D. Karaceper, Yannis Trakadis, John J. Mitchell, Pranesh Chakraborty, Kylie Tingley, Doug Coyle, Scott D. Grosse, Jonathan B. Kronick, Anne Marie Laberge, Julian Little, Chitra Prasad, Lindsey Sikora, Komudi Siriwardena, Rebecca Sparkes, Kathy N. Speechley, Sylvia Stockler, Brenda J. Wilson, Kumanan Wilson, Reem Zayed, Beth K. Potter, Valerie Austin, Annette Feigenbaum, Laura Nagy, Marni Brownwell, and Catherine Brunel
Nifedipine and phenytoin induce matrix synthesis, but not proliferation, in intact human gingival connective tissue ex vivo, Shawna S. Kim, Sarah Michelsons, Kendal Creber, Michael J. Rieder, and Douglas W. Hamilton
Clopidogrel and CYP2C19: Pharmacogenetic testing ready for clinical prime time?, Michael J. Knauer, Eleftherios P. Diamandis, Jean Sebastien Hulot, Richard B. Kim, and Derek Y.F. So
PTHrP-Related Hypercalcaemia in Infancy and Congenital Anomalies of the Kidney and Urinary Tract (CAKUT), Nardeen Kodous, Guido Filler, Ajay Parkash Sharma, and Tamara Angela Van Hooren
Development and validation of juvenile autoinflammatory disease multidimensional assessment report (JAIMAR), D. Konukbay, D. Yildiz, C. Acikel, B. Sozeri, B. Makay, N. A. Ayaz, K. Barut, A. Kisaarslan, Y. Bilginer, H. Peru, O. Erdogan, E. Unsal, O. Kasapcopur, Z. Gunduz, A. Ravelli, I. Kone-Paut, J. Frenkel, M. Gattorno, S. Ozen, and E. Demirkaya
Rapid fecal calprotectin testing to assess for endoscopic disease activity in inflammatory bowel disease: A diagnostic cohort study, Lukasz Kwapisz, Mahmoud Mosli, Nilesh Chande, Brian Yan, Melanie Beaton, Jessica Micsko, Pauline W. Mennill, William Barnett, Kevin Bax, Terry Ponich, John Howard, Anthony Tirolese, Robert Lannigan, and James Gregor
Endometrial ablation in the management of abnormal uterine bleeding, Philippe Laberge, Nicholas Leyland, Ally Murji, Claude Fortin, Paul Martyn, George Vilos, Wendy Wolfman, Catherine Allaire, Alaa Awadalla, Sheila Dunn, Mark Heywood, Madeleine Lemyre, Violaine Marcoux, Frank Potestio, David Rittenberg, Sukhbir Singh, and Grace Yeung
The putative tumor suppressor gene EphA3 fails to demonstrate a crucial role in murine lung tumorigenesis or morphogenesis, Jenni Lahtela, Barun Pradhan, Katja Närhi, Annabrita Hemmes, Merja Särkioja, Panu E. Kovanen, Arthur Brown, and Emmy W. Verschuren
Improved health-related quality of life after surgical management of severe refractory constipation-dominant irritable bowel syndrome, Jennifer Y. Lam, Biniam Kidane, Farouq Manji, and Brian M. Taylor
Treatment options for pediatric patent ductus arteriosus: Systematic review and meta-analysis, Jennifer Y. Lam, Steven R. Lopushinsky, Irene W.Y. Ma, Frank Dicke, and Mary E. Brindle
Metabolic clinic atlas: Organization of care for children with inherited metabolic disease in Canada, Monica F. Lamoureux, Kylie Tingley, Jonathan B. Kronick, Beth K. Potter, Alicia K.J. Chan, Doug Coyle, Linda Dodds, Sarah Dyack, Annette Feigenbaum, Michael Geraghty, Jane Gillis, Cheryl Rockman-Greenberg, Aneal Khan, Julian Little, Jennifer MacKenzie, Bruno Maranda, Aizeddin Mhanni, John J. Mitchell, Grant Mitchell, Anne Marie Laberge, Murray Potter, Chitra Prasad, Komudi Siriwardena, Kathy N. Speechley, Sylvia Stockler, and Yannis Trakadis