Microbiology & Immunology Publications

The media and probiotics: Provocation or dialogue?

Document Type

Article

Publication Date

1-1-1990

Journal

Infection and Immunity

Volume

58

Issue

6

First Page

2005

Last Page

2007

Abstract

All 25 strains of Candida spp. tested were able to grow in medium supplemented with 25% nonoxynol-9 in vitro. Adhesion of Candida spp. to HeLa cells was found to increase in the presence of 5% nonoxynol-9 (2.2- to 6.6-fold; P < 0.001) and, to a lesser extent, in 12.5% nonoxynol-9. Adhesion of Candida strains cultured in medium supplemented with nonoxynol-9 varied, with five of six strains of Candida albicans and the single strain of Candida tropicalis demonstrating increases of 1.4 to 4.0 times control levels (P < 0.05). The increased adhesion did not correlate with altered yeast cell surface hydrophobicity or germ tube formation.

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