The media and probiotics: Provocation or dialogue?

Authors

J. A. McGroarty, University of Toronto
F. Soboh, University of Toronto
A. W. Bruce, University of Toronto
G. Reid, University of Toronto

Document Type

Article

Publication Date

1-1-1990

Journal

Infection and Immunity

Volume

58

Issue

6

First Page

2005

Last Page

2007

Abstract

All 25 strains of Candida spp. tested were able to grow in medium supplemented with 25% nonoxynol-9 in vitro. Adhesion of Candida spp. to HeLa cells was found to increase in the presence of 5% nonoxynol-9 (2.2- to 6.6-fold; P < 0.001) and, to a lesser extent, in 12.5% nonoxynol-9. Adhesion of Candida strains cultured in medium supplemented with nonoxynol-9 varied, with five of six strains of Candida albicans and the single strain of Candida tropicalis demonstrating increases of 1.4 to 4.0 times control levels (P < 0.05). The increased adhesion did not correlate with altered yeast cell surface hydrophobicity or germ tube formation.