Date of Award

2010

Degree Type

Thesis

Degree Name

Master of Science

Program

Chemistry

Supervisor

Dr. Mark S. Workentin

Second Advisor

Dr. Keith Griffiths

Third Advisor

Dr. H.B. Kraatz

Abstract

The ability to manipulate the interfacial environment of monolayer protected gold nanoparticles (MPNs) is critical for the understanding and development in their potential application. While various methods for the incorporation of functionality onto MPNs are available, many require tedious synthesis dependant solely upon its application. A result of this is the development of a multifunctional MPN that can serve as a platform and has the potential to undergo multiple organic transformations at the interface, offering a powerful tool in the exploitation of the MPNs unique chemical environment. This thesis looks to examine the use of a maleimide modified-MPN as a template and its ability to undergo the 1,3-dipolar cycloaddition reaction with a series of nitrones under ambient and high-pressure conditions. Expanding the scope of this reaction to the investigation in synthesizing a nitrone modified-MPN and examine its ability to undergo the 1,3-dipolar cycloaddition reaction with a series of dipolarophiles under ambient and high-pressure conditions.

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