Date of Award

2011

Degree Type

Thesis

Degree Name

Master of Engineering Science

Program

Chemical and Biochemical Engineering

Supervisor

Dr. Jesse Zhu

Second Advisor

Dr. Hui Zhang

Abstract

Surface bio-contamination is a serious problem which contributes to outbreaks of nosocominal infection. An effective antimicrobial surface coating can significantly reduce the average surface population of pathogens available for transmission to a susceptible host. To respond to these problems, a functional antibacterial surface has been developed. For the use in medical devices, food industries, aviation sector and many other areas, a strong antibacterial property is required for the surface coating to effectively resist bacterial colonization. Recently, the introduction of new silver based antibacterial surfaces has drawn more attention not only for their non-toxicity of the activeAg ion to human cells but also of their novel ability of being a long lasting biocide.

A synthetic zeolite and three other natural zeolites have been selected in this work as carrier materials for silver. Silver acts as the active material that is incorporated within zeolite and blended with ultrafme polyester resin. It shows strong antibacterial properties against Escherichia coli. A commercially available sample has been selected to compare with all the experimental results. ICP-OES analysis shows the highest silver concentration being within the ion exchanged synthetic zeolite. Different polyester ultrafme powders have made with different ion exchanged zeolites and their antimicrobial efficacy tested by repeated use of the same coated chips followed by washing with liquid detergent and water. For final formulation, silver was incorporated into natural zeolite LBN (chabazite) through ion exchange with 0.05M silver nitrate for 24 hours at pH below 5.0 and IPC-OES analysis confirmed the amount of silver as 0.52% in the ultrafme coating powder. SEM and EDX analysis also show the uniform distribution and amount of silver within the coating respectively. The durability of coated chips show more than 99% reduction of microorganism even after ten consecutive uses. The coated chips were also characterized by checking the effectiveness against autoclave tests and accelerated weather tests as well as the antibacterial efficiency for each condition.

For high efficiency, the coating needs to have a certain amount of active component. The controlled silver release capability of the formulated coating with this concentration of silver is promising compared to the commercial counter parts. These coated surfaces have shown uniform homogeneous antibacterial properties with excellent durability for extended period.

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