Faculty

Science

Supervisor Name

Vojislava Grbic

Keywords

RNAi, Pesticide, Genetics

Description

Tetranychus urticae are a species of pests that are very problematic in agricultural environments, as they cause lots of damage to a wide variety of crops. One step in figuring out a solution to this problem is through the use of RNA interference. After synchronizing the spider mites, they are treated with the dsRNA solution. The dsRNA is cleavage inside the mite, and the siRNA fragments then bind to a target gene in hopes of homologous sequence recognition leading to knockout/deregulation of the target gene. After treatment, the mites are observed for multiple variables, primarily fecundity and survival. If a dsRNA sequence is effective, compared to control mites, the dsRNA-treated mites should have significantly lower survival and fecundity.

Acknowledgements

Thank you to Dr. Vojislava Grbic and all the members in the Grbic lab, the Western USRI program, and the faculty of Science.

Creative Commons License

Creative Commons Attribution-Noncommercial 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License

Document Type

Poster

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RNA-Interference as a Topical Pesticide

Tetranychus urticae are a species of pests that are very problematic in agricultural environments, as they cause lots of damage to a wide variety of crops. One step in figuring out a solution to this problem is through the use of RNA interference. After synchronizing the spider mites, they are treated with the dsRNA solution. The dsRNA is cleavage inside the mite, and the siRNA fragments then bind to a target gene in hopes of homologous sequence recognition leading to knockout/deregulation of the target gene. After treatment, the mites are observed for multiple variables, primarily fecundity and survival. If a dsRNA sequence is effective, compared to control mites, the dsRNA-treated mites should have significantly lower survival and fecundity.

 

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