Contralateral Breast Cancer With Multiple Primary Neoplasms in a Patient With Neurofibromatosis Type 1: A Case Report and Review of the Literature

Authors

Shifaz Veettil, Western University
Jawaid Younus, Western University
Edward Yu, Western University

Document Type

Article

Publication Date

March 2021

Journal

Cureus

Volume

13

Issue

3

First Page

e13738

URL with Digital Object Identifier

10.7759/cureus.13738

Abstract

Neurofibromatosis type 1 (NF1) is an autosomal dominant neuroectodermal disorder associated withincreased risk for several neural and non-neural malignancies. The link between NF1 and breast cancer hasrecently been established, with patients with NF1 being at higher risk for developing breast cancer, morelikely to get breast cancer at a younger age, and more likely to have their breast cancer present with moreadverse prognostic factors. Although rare, several cases of NF1 patients with contralateral breast cancerhave been mentioned in the literature. We report the case of one such patient who developed contralateralbreast cancer 40 years after her initial breast cancer diagnosis.

Notes

open access