"Early Steroid Withdrawal after Liver Transplantation: The Canadian Tac" by Paul Greig, Leslie Lilly et al.
 

Surgery Publications

Early Steroid Withdrawal after Liver Transplantation: The Canadian Tacrolimus versus Microemulsion Cyclosporin A Trial: 1-year Follow-up

Document Type

Article

Publication Date

6-2003

Journal

Liver Transplantation

Volume

9

Issue

6

First Page

587

Last Page

595

URL with Digital Object Identifier

http://dx.doi.org/10.1053/jlts.2003.50102

Abstract

Corticosteroid therapy contributes significant toxicity to liver transplantation. The safety and efficacy of early steroid withdrawal were determined in patients treated with either tacrolimus or microemulsion cyclosporin A (micro-CsA). The primary outcome was the proportion of patients who were steroid-free 1 year posttransplantation. From the seven Canadian adult liver transplant centers, 143 patients were randomly allocated oral treatment with either tacrolimus (n = 71) or micro-CsA (n = 72), together with corticosteroids and azathioprine. Eligibility criteria for steroid withdrawal included freedom from acute rejection for a minimum of 3 months, and prednisone

Notes

Dr. Vivian McAlister is currently a faculty member at The University of Western Ontario.

Find in your library

Plum Print visual indicator of research metrics
PlumX Metrics
  • Citations
    • Citation Indexes: 57
    • Policy Citations: 2
  • Usage
    • Abstract Views: 79
  • Captures
    • Readers: 61
see details

Share

COinS