Pharmacology and Toxicology Theses and Dissertations
This collection contains theses and dissertations from the Department of Pharmacology and Toxicology, collected from the Scholarship@Western Electronic Thesis and Dissertation Repository
Theses/Dissertations from 2017
The Effects of Acetylenic Tricyclic Bis-(Cyano Enone) on Cell Migration, Eddie Chan
Regulation of Cardiac Hypertrophy and Metabolism by Regulator of G Protein Signalling 2 (RGS2), Katherine N. Lee
Theses/Dissertations from 2016
Effects of Prenatal Exposure to Bisphenol A on Fetal Lung Development, Ayten Hijazi
Regulation of E2F1 in Keratinocytes During UV-Damage and Differentiation, Randeep K. Singh
Theses/Dissertations from 2015
Quantitative Estimation of P-glycorptein-Mediated Drug Transport by Mechanistically Modeled Intrinsic Clearance, Alex D. Morgan
Epidermal Growth Factor Receptor in Joint Health and Osteoarthritis, Michael A. Pest
Regulation of Hepatic Drug Metabolizing Enzymes in Chronic Kidney Disease, Thomas J. Velenosi
Theses/Dissertations from 2014
American Ginseng Modulation of Immune Function and Phytochemical Analysis, Chike G. Azike
Analysis of the Vascular Phenotype of the ENT1-null mouse, Keisha A. Best
Cortisol and Testosterone in Hair as Biological Markers of Systolic Heart Failure, Justin Chan
Regulation of the High-Affinity Choline Transporter Activity and Trafficking in Alzheimer’s Disease-Related Pathological Conditions, Leah K. Cuddy
Erythropoietin and Chronic Kidney Disease Alter Hepatic Expression of Cytochrome P450 Enzymes and Drug Transport Proteins, David A. Feere
The Role of c-Kit Receptor Tyrosine Kinase in Beta-Cell Proliferation, Function and Survival, Zhi Chao Feng
The Effects of Atypical Protein Kinase C on TGFβ Signalling, Adrian D. Gunaratne
Investigating Risk Factors for Pediatric Opioid Morbidity and Mortality, Lauren E. Kelly
Role Of Nitric Oxide In Embryonic Heart Development And Adult Aortic Valve Disease, Yin Liu
The ATP2C2 Gene as Transcribed from a Novel Transcriptional Start Site in Pancreatic Acinar Cells, Caitlin M. Sullivan
Effect of Ascorbate on Coagulation and Fibrinolytic Factors in the Septic Microvasculature, Scott Swarbreck
In Vitro Functional Analysis Of Novel Single Nucleotide Polymorphisms In OATP1B1 And Potential Clinical Relevance, Zhiyuan P. Yin
Theses/Dissertations from 2013
Role of iNOS in septic pulmonary microvascular endothelial cell activation, Zahra Asad
ER stress coupled pannexin channel activation via STIM proteins, Ankur Bodalia
Pharmacogenetics of Oral Anticoagulants and Antiplatelets, Inna Gong
N-acetylcysteine as a chemoprotectant against ifosfamide nephrotoxicity; from mechanism to prevention, Lauren Hanly
Fetal and Neonatal Exposure to Nicotine Augments Hepatic Fatty Acid Synthesis in Rat Offspring Long-Term, Noelle L. Ma
Reorganization of inhibitory synapses in experimental epilepsy, Emily J. Pollock
Mechanism of Ascorbate Protection Against Sepsis-Induced Capillary Blood Flow Impairment, Dan Secor
Theses/Dissertations from 2012
Statin Transport by Hepatic Organic Anion-Transporting Polypeptides (OATPs), Marianne K. DeGorter
The Role of Drug Transporters in Statin-Induced Myopathy, Michael J. Knauer
The role of GRK2 in hypertension and regulation of GPR30, Bonan Liu
Methodological Challenges and Clinical Applications of Hair Cortisol Analysis, Evan W. Russell
Intestinal and hepatic drug transporters and their role in the disposition of lipid-lowering drugs, Ute I. Schwarz
Molecular Mechanisms of Cell Migration Inhibition by Synthetic Triterpenoids, Ciric Chi Wing To
Characterization of EIF2Be and Its Interaction with RGS2, William H. Xue
Theses/Dissertations from 2011
Purine Transport and Metabolism in Microvascular Endothelial Cells, Derek B J Bone
Predicting Drug Hypersensitivity Reactions: Mechanistic and Clinical Implications, Abdelbaset A. Elzagallaai
Regulation of G Protein Signaling by GoLoco Motif Containing Proteins, Peishen Zhao
Theses/Dissertations from 2010
Pharmacokinetics and Therapeutic Uses of Mesna, Murray J. Cutler
Regulation of DNA Damage Processing by Covalent Modification of Thymine DNA Glycosylase, Ryan D. Mohan