Paediatrics Publications
Research in The Department of Paediatrics at Schulich School of Medicine & Dentistry is divided into eighteen areas of focus. These areas include cardiology, child development, critical care medicine, endocrinology/diabetes, genetics/metabolics, infectious disease, and neurology.
Submissions from 2020
Determining a Bayesian predictive power stopping rule for futility in a non-inferiority trial with binary outcomes., Anna Heath, Martin Offringa, Petros Pechlivanoglou, Juan David Rios, Terry P Klassen, Naveen Poonai, and Eleanor Pullenayegum
Determining a Bayesian predictive power stopping rule for futility in a non-inferiority trial with binary outcomes., Anna Heath, Martin Offringa, Petros Pechlivanoglou, Juan David Rios, Terry P Klassen, Naveen Poonai, and Eleanor Pullenayegum
A pragmatic randomized controlled trial of multi-dose oral ondansetron for pediatric gastroenteritis (the DOSE-AGE study): statistical analysis plan., Anna Heath, Juan David Rios, Sarah Williamson-Urquhart, Petros Pechlivanoglou, Martin Offringa, Christopher McCabe, Gareth Hopkin, Amy C Plint, Andrew Dixon, Darcy Beer, Serge Gouin, Gary Joubert, Terry P Klassen, and Stephen B Freedman
Non-steroidal or opioid analgesia use for children with musculoskeletal injuries (the No OUCH study): statistical analysis plan., Anna Heath, Maryna Yaskina, Gareth Hopkin, Terry P Klassen, Christopher McCabe, Martin Offringa, Petros Pechlivanoglou, Juan David Rios, Naveen Poonai, and Samina Ali
A National Spinal Muscular Atrophy Registry for Real-World Evidence., Victoria L Hodgkinson, Maryam Oskoui, Joshua Lounsberry, Saïd M'Dahoma, Emily Butler, Craig Campbell, Alex MacKenzie, Hugh J McMillan, Louise Simard, Jiri Vajsar, Bernard Brais, Kristine M Chapman, Nicolas Chrestian, Meghan Crone, Peter Dobrowolski, Susan Dojeiji, James J Dowling, Nicolas Dupré, Angela Genge, Hernan Gonorazky, Simona Hasal, Aaron Izenberg, Wendy Johnston, Edward Leung, Hanns Lochmüller, Jean K Mah, Alier Marerro, Rami Massie, Laura McAdam, Anna McCormick, Michel Melanson, Michelle M Mezei, Cam-Tu E Nguyen, Colleen O'Connell, Erin K O'Ferrall, Gerald Pfeffer, Cecile Phan, Stephanie Plamondon, Chantal Poulin, Xavier Rodrigue, Kerri L Schellenberg, Kathy Selby, Jordan Sheriko, Christen Shoesmith, Garth Smith, Monique Taillon, Sean Taylor, Jodi Warman Chardon, Scott Worley, and Lawrence Korngut
Mitochondrial DNA Copy Number and Incident Heart Failure: The Atherosclerosis Risk in Communities (ARIC) Study, Yun Soo Hong, Ryan J. Longchamps, Di Zhao, Christina A. Castellani, Laura R. Loehr, Patricia P. Chang, Kunihiro Matsushita, Megan L. Grove, Eric Boerwinkle, Dan E. Arking, and Eliseo Guallar
A critical examination of legal and ethical considerations for nutrigenetic testing with recommendations for improving regulation in Canada: From science to consumer, Justine Horne, Jason Gilliland, Janet Madill, and Jacob Shelley
Exploring attitudes, subjective norms and perceived behavioural control in a genetic-based and a population-based weight management intervention: A one-year randomized controlled trial, Justine R. Horne, Jason A. Gilliland, Marie Claude Vohl, and Janet Madill
Can a Lifestyle Genomics Intervention Motivate Patients to Engage in Greater Physical Activity than a Population-Based Intervention? Results from the NOW Randomized Controlled Trial, Justine R. Horne, Jason Gilliland, Tara Leckie, Colleen O'Connor, Jamie A. Seabrook, and Janet Madill
Can a Lifestyle Genomics Intervention Motivate Patients to Engage in Greater Physical Activity than a Population-Based Intervention? Results from the NOW Randomized Controlled Trial, Justine R. Horne, Jason Gilliland, Tara Leckie, Colleen O'Connor, Jamie A. Seabrook, and Janet Madill
Assessing the validity of the past-month, online canadian diet history questionnaire ii pre and post nutrition intervention, Justine R. Horne, Jason Gilliland, and Janet Madill
Magnetic resonance imaging of obesity and metabolic disorders: Summary from the 2019 ISMRM Workshop, Houchun H. Hu, Rosa Tamara Branca, Diego Hernando, Dimitrios C. Karampinos, Jürgen Machann, Charles A. McKenzie, Holden H. Wu, and Takeshi Yokoo
Recognizing and addressing implicit gender bias in medicine, Katrina Hui, Javeed Sukhera, Simone Vigod, Valerie H. Taylor, and Juveria Zaheer
DRM02, a novel phosphodiesterase-4 inhibitor with cutaneous anti-inflammatory activity, David W.C. Hunt, Iordanka A. Ivanova, and Lina Dagnino
Performance of early pregnancy HbA1c for predicting gestational diabetes mellitus and adverse pregnancy outcomes in obese European women, Jincy Immanuel, David Simmons, Gernot Desoye, Rosa Corcoy, Juan M. Adelantado, Roland Devlieger, Annunziata Lapolla, and Maria G. Dalfra
Organizational guidance for the care of patients with head-and-neck cancer in Ontario., J Irish, J Kim, J Waldron, A C Wei, E Winquist, J Yoo, A Boasie, M Brouwers, E Meertens, S McNair, and C Walker-Dilks
The case for cautious interpretation and replication: Lead-time bias as a potential explanation for the link between duration of untreated psychosis and outcome, Srividya N. Iyer, Kelly K. Anderson, Ashok Malla, Jai Shah, and Ross Norman
Osteochondritis Dissecans in Pediatric Patients with Juvenile Idiopathic Arthritis., Bradley C Jackson, Debra L Bartley, and Roberta A Berard
Seizure freedom improves health-related quality of life after epilepsy surgery in children., Puneet Jain, Mary Lou Smith, Kathy Speechley, Mark Ferro, Mary Connolly, Rajesh Ramachandrannair, Salah Almubarak, Andrea Andrade, and Elysa Widjaja
Down-regulation of placental Cdc42 and Rac1 links mTORC2 inhibition to decreased trophoblast amino acid transport in human intrauterine growth restriction., Thomas Jansson, Marisol Castillo-Castrejon, Madhulika B Gupta, Theresa L Powell, and Fredrick J Rosario
The Transcription Factor OVOL2 Represses ID2 and Drives Differentiation of Trophoblast Stem Cells and Placental Development in Mice, Mariyan J. Jeyarajah, Gargi Jaju Bhattad, Dendra M. Hillier, and Stephen J. Renaud
Pain Squad+ smartphone app to support real-time pain treatment for adolescents with cancer: protocol for a randomised controlled trial., Lindsay Jibb, Paul C Nathan, Vicky Breakey, Conrad Fernandez, Donna Johnston, Victor Lewis, Sarah McKillop, Serina Patel, Christine Sabapathy, Caron Strahlendorf, J Charles Victor, Myla E Moretti, Cynthia Nguyen, Amos Hundert, Celia Cassiani, Graziella El-Khechen Richandi, Hayley Insull, Rachel Hamilton, Geoffrey Fang, Susan Kuczynski, and Jennifer Stinson
DLC1 SAM domain-binding peptides inhibit cancer cell growth and migration by inactivating RhoA, Rakesh Joshi, Lyugao Qin, Xuan Cao, Shanshan Zhong, Courtney Voss, Weiping Min, and Shawn S.C. Li
Hyperphosphorylation of fetal liver IGFBP-1 precedes slowing of fetal growth in nutrient-restricted baboons and may be a mechanism underlying IUGR, Jenica H Kakadia, Bhawani B. Jain, Kyle Biggar, Austin Sutherland, Karen Nygard, Cun Lee, Peter W Nathanielsz, Thomas Jansson, and Madhulika B. Gupta Dr.
Perspectives and impact of a parent-child intervention on dietary intake and physical activity behaviours, parental motivation, and parental body composition: A randomized controlled trial, Shazya Karmali, Danielle S. Battram, Shauna M. Burke, Anita Cramp, Andrew M. Johnson, Tara Mantler, Don Morrow, Victor Ng, Erin S. Pearson, Robert J. Petrella, Patricia Tucker, and Jennifer D. Irwin