Guideline for the Prevention of Acute Chemotherapy-Induced Nausea and Vomiting in Pediatric Cancer Patients: A focused update

Authors

Priya Patel, University of Toronto
Paula D Robinson, Pediatric Oncology Group of Ontario
Jennifer Thackray, Memorial Sloan Kettering Cancer Center
Jacqueline Flank, The Hospital for Sick Children
Mark T Holdsworth, University of New Mexico
Paul Gibson, London Health Sciences Centre
Andrea Orsey, University of Connecticut School of Medicine
Carol Portwine, McMaster University
Jason Freedman, University of Pennsylvania
Jennifer R Madden, University of Colorado
Robert Phillips, University of York
Lillian Sung, The Hospital for Sick Children
L Lee Dupuis, The Hospital for Sick Children

Document Type

Article

Publication Date

10-2017

Journal

Pediatric Blood & Cancer

Volume

64

Issue

10

URL with Digital Object Identifier

https://doi.org/10.1002/pbc.26542

Abstract

This update of the 2013 clinical practice guideline provides clinicians with guidance regarding the use of aprepitant and palonosetron for the prevention of acute chemotherapy-induced nausea and vomiting (CINV) in children. The recommendations were based on three systematic reviews. Substantive changes were made to the guideline recommendations including the inclusion of palonosetron to the 5-HT