Paediatrics Publications
Document Type
Article
Publication Date
4-1-2021
Journal
Paediatrics and Child Health (Canada)
Volume
26
Issue
2
First Page
e96
Last Page
e104
URL with Digital Object Identifier
https://doi.org/10.1093/pch/pxz143
Abstract
Objective: Survivors of extremely preterm birth are at risk of re-hospitalization but risk factors in the Canadian population are unknown. Our objective is to identify neonatal, sociodemographic, and geographic characteristics that predict re-hospitalization in Canadian extremely preterm neonates. Methods: This is a retrospective analysis of a prospective observational cohort study that included preterm infants born 22 to 28 weeks’ gestational age from April 1, 2009 to September 30, 2011 and seen at 18 to 24 months corrected gestational age in a Canadian Neonatal Follow-Up Network clinic. Characteristics of infants re-hospitalized versus not re-hospitalized are compared. The potential neonatal, sociodemographic, and geographic factors with significant association in the univariate analysis are included in a multivariate model. Results: From a total of 2,275 preterm infants born at 22 to 28 weeks gestation included, 838 (36.8%) were re-hospitalized at least once. There were significant disparities between Canadian provincial regions, ranging from 25.9% to 49.4%. In the multivariate logistic regression analysis, factors associated with an increased risk for re-hospitalization were region of residence, male sex, bronchopulmonary dysplasia, necrotizing enterocolitis, prolonged neonatal intensive care unit (NICU) stay, ethnicity, Indigenous ethnicity, and sibling(s) in the home. Conclusion: Various neonatal, sociodemographic, and geographic factors predict re-hospitalization of extremely preterm infants born in Canada. The risk factors of re-hospitalization provide insights to help health care leaders explore potential preventative approaches to improve child health and reduce health care system costs
Notes
On behalf of the Canadian Neonatal Follow-Up Network: Thevanisha Pillay, MD, Victoria General Hospital, Victoria, B.C. Anne Synnes, MDCM, MHSC, British Columbia Women’s Hospital, Vancouver, B.C. Leonora Hendson MB.BCH, MSc, Alberta’s Children’s Hospital, Foothills Medical Centre, Calgary, AB Amber Reichert, MD, Glenrose Rehabilitation Hospital, Edmonton, AB Jaya Bodani, MD, Regina General Hospital, Regina, SK Sibasis Daspal, MD, Royal University Hospital, Saskatoon, SK Diane Moddemann, MD, Cecilia de Cabo, Winnipeg Health Sciences Centre, St. Boniface General Hospital, Winnipeg, MB Chukwuma Nwaesei, MD, Windsor Regional Hospital, Windsor, ON Thierry Daboval, MD, Children’s Hospital of Eastern Ontario, Ottawa, ON Sarah McKnight, Kingston General Hospital, Kingston, ON Kevin Coughlin, MD, Children’s Hospital London Health Sciences Centre, London, ON Linh Ly, MD, Hospital for Sick Children, Toronto, ON Edmond Kelly, MD, Mount Sinai Hospital, Toronto, ON Saroj Saigal, Karen Thomas, MD, Hamilton Health Sciences Centre, Hamilton, ON Paige Church, MD, Sunnybrook Health Sciences Centre, Toronto, ON Ermelinda Pelausa, MD, Jewish General Hospital, Montréal, QC M Khairy MD, Montréal Children’s Hospital, Royal Victoria Hospital, Montréal, QC Thuy Mai Luu MD, MSc, Centre Hospitalier Universitaire SainteJustine, Montréal, QC Charlotte Demers and Dr. Alyssa Morin, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC Sylvie Bélanger, MD, Centre Hospitalier Universitaire de Québec, Québec City, QC Roderick Canning, MD, Moncton Hospital, Moncton, N.B. Luis Monterrosa, MD, Saint John Regional Hospital, Saint John, N.B. Hala Makary, MD, Dr. Everett Chalmers Hospital, Fredericton, N.B. Jehier Afifi, MB BCh, MSc, IWK Health Centre, Halifax, N.S. Phil Murphy, Charles Janeway Children’s Health and Rehabilitation Centre, St. John’s, NL.