Paediatrics Publications
Non-invasive measurement of cardiac output in children with repaired coarctation of the aorta using electrical cardiometry compared to transthoracic Doppler echocardiography.
Document Type
Article
Publication Date
5-17-2018
Journal
Physiological Measurement
Volume
39
Issue
5
First Page
055003
Last Page
055003
URL with Digital Object Identifier
https://doi.org/10.1088/1361-6579/aac02b
Abstract
Objective
To evaluate the equivalence of the ICON
Approach
A group of n = 28 CoA patients and n = 27 matched controls were enrolled. EC and TTE were performed synchronously on each participant and CO measurements compared using linear regression and Bland-Altman analysis. The CoA group was further subdivided into two groups, with n = 10 and without n = 18 increased left ventricular outflow tract velocity (iLVOTv) for comparison.
Main Results
CO measurements from EC and TTE in controls showed a strong correlation (R = 0.80, p < 0.001) and an acceptable percentage error (PE) of 28.1%. However, combining CoA and control groups revealed a moderate correlation (R = 0.57, p < 0.001) and a poor PE (44.2%). We suspected that the CO in a subset of CoA participants with iLVOTv was overestimated by TTE. Excluding the iLVOTv CoA participants improved the correlation (R = 0.77, p < 0.001) and resulted in an acceptable PE of 31.2%.
Significance
CO measurements in paediatric CoA patients in the absence of iLVOTv are clinically equivalent between EC and TTE. The presence of iLVOTv may impact the accuracy of CO measurement by TTE, but not EC.
Notes
Article available at Physiological Measurement, Vol. 39(5)
https://doi.org/10.1088/1361-6579/aac02b