Pediatric Oncology Clinical Trial Participation Where the Geography is Vast: Development of a clinical research system for tertiary and satellite centers in Ontario, Canada.

Authors

Sarah Alexander, University of Toronto
Mark Greenberg, University of Toronto
David Malkin, University of Toronto
Carol Portwine, McMaster Children's Hospital
Donna Johnston, Children's Hospital of Eastern
Mariana Silva, Kingston General Hospital
Shayna Zelcer, Western University
Samantha Sonshine, University of Toronto
Janet Manzo, Ontario Institute for Cancer Research
Carla Bennett, Pediatric Oncology Group of Ontario
Kathy Brodeur-Robb, C17 Council for Children's Cancer and Blood Disorders
Catherine Deveault, University of Toronto
Nivetha Ramachandran, University of Toronto
Paul Gibson, Western University

Document Type

Article

Publication Date

4-2018

Journal

Pediatric Blood & Cancer

Volume

65

Issue

4

URL with Digital Object Identifier

https://doi.org/10.1002/pbc.26901

Abstract

Opportunities for participation in clinical trials are a core component of the care of children with cancer. In Ontario, many pediatric patients live long distances from their cancer center. This paper describes the work that was done in order to allow patients participating in Children's Oncology Group trials to receive care, including research protocol related care, jointly between the tertiary pediatric cancer center and the closer-to-home satellite center. The system is a pragmatic risk-based model, supporting excellence in care while ensuring good conduct of the research in compliance with applicable regulations and guidelines, including ethics oversight.