Paediatrics Publications
Document Type
Article
Publication Date
5-1-2011
Journal
Genes and Development
Volume
25
Issue
9
First Page
889
Last Page
894
URL with Digital Object Identifier
10.1101/gad.2050411
Abstract
The Hippo pathway coordinates organ size and cell proliferation. The retinoblastoma family of proteins regulates progression through the G0/G1 phase of the cell cycle. Disruption of either pathway contributes to cancer formation. Three recent studies in Genes & Development reveal how cellular proliferation is coordinated between these pathways. Here we discuss the implications of these studies and the new questions that they raise. © 2011 by Cold Spring Harbor Laboratory Press.
COinS