Oncology Publications
Title
Tumour Dormancy in Breast Cancer: An Update
Document Type
Article
Publication Date
5-31-2007
Journal
Breast Cancer Research
Volume
9
Issue
208
Abstract
Delayed recurrences, common in breast cancer, are well explained by the concept of tumour dormancy. Numerous publications describe clinical times to disease recurrence or death, using mathematical approaches to infer mechanisms responsible for delayed recurrences. However, most of the clinical literature discussing tumour dormancy uses data from over a half century ago and much has since changed. This review explores how current breast cancer treatment could change our understanding of the biology of breast cancer tumour dormancy, and summarizes relevant experimental models to date. Current knowledge gaps are highlighted and potential areas of future research are identified.
Notes
Published in: Breast Cancer Research, 2007, 9:208. doi:10.1186/bcr1677