Title

What Factors Predict Outcome at Relapse after Previous Esophagectomy and Adjuvant Therapy in High-Risk Esophageal Cancer?

Authors

Edward Yu, University of Western OntarioFollow
Patricia Tai, Allan Blair Cancer Center, Regina, SK
Richard Malthaner, University of Western OntarioFollow
Larry Stitt, University of Western OntarioFollow
George Rodrigues, University of Western OntarioFollow
Rashid Dar, University of Western OntarioFollow
Brian Yaremko, University of Western OntarioFollow
Jawaid Younus, University of Western OntarioFollow
Michael Sanatani, University of Western OntarioFollow
Mark Vincent, University of Western OntarioFollow
Brian Dingle, University of Western OntarioFollow
Dalilah Fortin, University of Western OntarioFollow
Richard Inculet, University of Western OntarioFollow

Document Type

Presentation

Publication Date

10-2009

Abstract

Management of patients who have disease relapse after completion of surgery and adjuvant chemo-radiation (CRT) is controversial.

Some oncologists would advocate intensive therapeutic intervention due to promising experience on treatment for recurrence disease while others would recommend palliative support due to the concerns for poor patient outcome post disease recurrence.

In Addition, it is not clear if patient outcome is improved post adjuvant CRT when patients at risk have resection margin involvement and if time interval to recurrence can affect patient survival post relapse.

The present study was conducted to determine what factors will affect patient outcome at relapse after previous surgery and adjuvant CRT in high-risk esophageal cancer patients

This clinical information may be useful in providing appropriate guidance for oncologists to manage esophageal cancer patients after disease relapse.

Notes

Presentation at the Canadian Association of Radiation Oncologists (CARO) Annual Scientific Meeting in Québec City in Oct. 2009